3-Bromopropionic acid
- CAS No.
- 590-92-1
- Chemical Name:
- 3-Bromopropionic acid
- Synonyms
- 3-Bromopropanoic acid;Valine Impurity 30;3-Bromoprpionicacid;-Bromopropionicacid;RARECHEM AL BO 0160;3-bromopropanoicacid;3-bromo-propanoicaci;3-bromo-propionicaci;3-BROMPROPIONIC ACID;3-bromo-Propanoicacid
- CBNumber:
- CB7177280
- Molecular Formula:
- C3H5BrO2
- Molecular Weight:
- 152.97
- MOL File:
- 590-92-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/3 12:56:46
| Melting point | 58-62 °C(lit.) |
|---|---|
| Boiling point | 140-142 °C (45 mmHg) |
| Density | 1.48 g/mL at 25 °C(lit.) |
| refractive index | 1.4753 (estimate) |
| Flash point | 150 °F |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear |
| form | Crystals or Crystalline Powder |
| pka | 4.00(at 25℃) |
| color | White to slightly yellow |
| Water Solubility | 0.1 g/mL |
| Merck | 14,1433 |
| BRN | 1071333 |
| Dielectric constant | 11.0（20℃） |
| CAS DataBase Reference | 590-92-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 3-bromo-(590-92-1) |
| EPA Substance Registry System | Propanoic acid, 3-bromo- (590-92-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| Hazard Codes | F,C | |||||||||
| Risk Statements | 11-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UE7875000 | |||||||||
| Hazard Note | Corrosive/Highly Flammable | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159080 | |||||||||
| NFPA 704 |
|
3-Bromopropionic acid price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 101281 | 3-Bromopropionic acid 97% | 590-92-1 | 100G | ₹4390 | 2022-06-14 | Buy |
| ALFA India | ALF-A11573-36 | 3-Bromopropionic acid, 97% | 590-92-1 | 500g | ₹10751 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B0645 | 3-Bromopropionic Acid min. 98.0 % | 590-92-1 | 25G | ₹2100 | 2022-05-26 | Buy |
| ALFA India | ALF-A11573-22 | 3-Bromopropionic acid, 97% | 590-92-1 | 100g | ₹3647 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B0645 | 3-Bromopropionic Acid min. 98.0 % | 590-92-1 | 100G | ₹4000 | 2022-05-26 | Buy |
3-Bromopropionic acid Chemical Properties,Uses,Production
Chemical Properties
white to pale yellow or orange crystalline. soluble in water, alcohol, ether, chloroform, benzene. Hydrolysis in alkaline solution generates hydroxypropionic acid. Corrosive. for organic synthesis.
Uses
3-Bromopropionic acid used as quaternization agent in amperometric biosensors.
Application
3-Bromopropionic acid is a widely used chemical intermediate. It can be used as a starting material to synthesize derivatives such as esters, acid halides and amides; the active group bromine can undergo a series of reactions, and is mainly used in the fields of pesticides and medicines. Such as the pesticides diflufenacil, furalax and so on.
Preparation
3-Bromopropionic acid is prepared by reacting acrylonitrile with hydrogen bromide to obtain bromopropionitrile and then hydrolyzing it. Add acrylonitrile to boiling hydrobromic acid, reflux at 130°C for 6 hours, extract the solid obtained by filtration with ethanol, and obtain the crude product after recovering ethanol by distillation under reduced pressure. By heating 2-cyanoethanol and 40% hydrobromic acid to reflux for 2h, 3-bromopropionic acid can also be produced with a yield of over 80%.
Safety Profile
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.
Purification Methods
The acid crystallises as plates from CCl4. It is soluble in organic solvents and H2O. Its methyl ester has b 65o/18mm and 80o/27mm. The S-benzylisothiouronium salt has m 136o. [Kendall & McKenzie Org Synth Coll Vol I 131 1941, Beilstein 2 IV 764.]
3-Bromopropionic acid Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| Faluck International | +91-7922705556 +91-9825549375 | Gujarat, India | 42 | 58 | Inquiry |
| Deep Pharm Chem Pvt Ltd | +91-9825070962 +91-9821380820 | Mumbai, India | 6 | 58 | Inquiry |
| Arene Life Sciences Limited | 09866147700 | Hyderabad, India | 166 | 58 | Inquiry |
| SPB Pharma Chiemimpex | 91-9043046289 | Tamil Nadu, India | 94 | 58 | Inquiry |
| Faluck International | 08048372661Ext 922 | Ahmedabad, India | 31 | 58 | Inquiry |
| Yasham Chemphar Private Limited | +91 22 40639900 | Mumbai, India | 31 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| JSK Chemicals | 58 |
| Sri Neelima Laboratories | 58 |
| Faluck International | 58 |
| Deep Pharm Chem Pvt Ltd | 58 |
| Arene Life Sciences Limited | 58 |
| SPB Pharma Chiemimpex | 58 |
| Faluck International | 58 |
| Yasham Chemphar Private Limited | 58 |
| HiMedia Laboratories | 58 |
| Reax Chemicals | 58 |