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Clobetasol propionate

Clobetasol propionate Structure
CAS No.
25122-46-7
Chemical Name:
Clobetasol propionate
Synonyms
CLOBETASOLE PROPIONATE;Olux;Clobex;Temovate;CLOBETASOL-17-PROPIONATE;Psorex;Olux-E;cgp9555;GR-2/92;Karison
CBNumber:
CB6274337
Molecular Formula:
C25H32ClFO5
Molecular Weight:
466.97
MOL File:
25122-46-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:13

Clobetasol propionate Properties

Melting point 195.5-1970C
alpha D +103.8° (c = 1.04 in dioxane)
Boiling point 569.0±50.0 °C(Predicted)
Density 1.1653 (estimate)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 per cent).
pka 12.88±0.70(Predicted)
form Solid
color White to off-white
InChIKey CBGUOGMQLZIXBE-XGQKBEPLSA-N
SMILES O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,16,18,20,23,r|
CAS DataBase Reference 25122-46-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360Df-H373-H413
Precautionary statements  P201-P273-P308+P313
Hazard Codes  Xi,T
Risk Statements  36/37/38-62-53-48/20/21-61
Safety Statements  26-36-45-36/37-53
WGK Germany  2
RTECS  TU3725000
HS Code  29372290
NFPA 704
0
2 0

Clobetasol propionate price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C8037 Clobetasol propionate analytical standard 25122-46-7 100MG ₹6570.78 2022-06-14 Buy
Sigma-Aldrich(India) PHR1921 Clobetasol Propionate Pharmaceutical Secondary Standard; Certified Reference Material 25122-46-7 500MG ₹23739.23 2022-06-14 Buy
Sigma-Aldrich(India) C8037 Clobetasol propionate analytical standard 25122-46-7 1G ₹34769.9 2022-06-14 Buy
TCI Chemicals (India) C2612 Clobetasol 17-Propionate 25122-46-7 1G ₹4200 2022-05-26 Buy
TCI Chemicals (India) C2612 Clobetasol 17-Propionate 25122-46-7 5G ₹10800 2022-05-26 Buy
Product number Packaging Price Buy
C8037 100MG ₹6570.78 Buy
PHR1921 500MG ₹23739.23 Buy
C8037 1G ₹34769.9 Buy
C2612 1G ₹4200 Buy
C2612 5G ₹10800 Buy

Clobetasol propionate Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Topical corticosteroid. Glucocorticoid; anti-inflammatory.
Clobetasol Propionate
Clobetasol propionate (Cormax, Temovate, Embeline, Olux) is one of the most potent of the currently available agents and is indicated for short-term treatment of inflammatory or hyperplastic disorders. It is a synthetic fluorinated corticosteroid. It may cause a more rapid or prolonged response than other topical corticosteroids. It is recommended that clobetasol have a maximum application of 60 g/week for no longer than 14 days without occlusion and that it should not be used in children below age 12.

Indications

Clobetasol propionate (Cormax, Temovate, Embeline, Olux) is one of the most potent of the currently available agents and is indicated for short-term treatment of inflammatory or hyperplastic disorders. It is a synthetic fluorinated corticosteroid. It may cause a more rapid or prolonged response than other topical corticosteroids. It is recommended that clobetasol have a maximum application of 60 g/week for no longer than 14 days without occlusion and that it should not be used in children below age 12.

Definition

ChEBI: The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis.

Clobetasol propionate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 757)Suppliers
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Maharshi Pharma Chem +91-7940359347 +91-7433927173 Gujarat, India 24 58 Inquiry

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Clobetasol propionate Spectrum

17-propionate cgp9555 Clobetasol 17- propionate solution,100ppm Cloβsol propionate 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate CLOBETASOL 17-PROPIONATE USP [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Dermovate GR-2/92 Psorex CLOBETASOLPROPIONATE,MICRONIZED CLOBETASOLPROPIONATE,MICRONIZED,USP 21-Chloro-21-deoxybetamethasone 17-propionate CCl 4725 Clobederm Dermoval Dermoxinale GR 2/925 Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)- Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methyl-, 17-propionate (8CI) 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione=17-propionate 21-Chloro-9α-fluoro-11β-hydroxy-16β-methyl-17α-propionyloxy-1,4-pregnadiene-3,20-dione Propionic acid clobetasol Clobetasol Propionate (200 mg) clobesol pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me CLOBESTASOL PROPIONATE CLOBETASOL PROPIONATE 21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate Pregna-1,4-Diene-3,20-Dione,21-Chloro-9-Fluoro-11-Hydroxy-16-Methyl-17-(1-Oxopropoxy)-,(11Beta,16Beta)- Clobetasolpropionatmikron. 21-Chloro-9-fluoro-11b Clobetasol Propionate (200 mg)F2C309980ug/mg(ai) Clobetasol Propionate-d5 21-Chloro-9alpha-fluoro-11beta,17alpha-dihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17-Propionate Karison Olux-E Skin Cap (11β,16β)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-d propanoic acid [(9R,17R)-17-(2-chloro-1-oxoethyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester Clobetasol Propionate 25122-46-7 Skin Disease Corticosteroids Raw Powder Clobetasol Propionate 25122-46-7 Clobetasol propionate CRS Clobetasol Propionate RS Cloβsol17-Propionate> Clobetasol for peak identification CRS obetasoL 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Clobetasol-[d5] 17-propionate Clobetasol propionate USP/EP/BP Clobetazole propionate Clobetasol propionate (Y0000559)Q: What is Clobetasol propionate (Y0000559) Q: What is the CAS Number of Clobetasol propionate (Y0000559) Clobetasol for peak identification (Y0000570) Clobetasol PropionateQ: What is Clobetasol Propionate Q: What is the CAS Number of Clobetasol Propionate Q: What is the storage condition of Clobetasol Propionate Q: What are the applications of Clobetasol Propionate Cloβsol 17-propionate D3 Clobetasol Propionate (1138405) Olux