Clobetasol propionate
![Clobetasol propionate Structure](CAS/GIF/25122-46-7.gif)
- CAS No.
- 25122-46-7
- Chemical Name:
- Clobetasol propionate
- Synonyms
- CLOBETASOLE PROPIONATE;Olux;Clobex;Temovate;CLOBETASOL-17-PROPIONATE;Psorex;Olux-E;cgp9555;GR-2/92;Karison
- CBNumber:
- CB6274337
- Molecular Formula:
- C25H32ClFO5
- Molecular Weight:
- 466.97
- MOL File:
- 25122-46-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:13
Melting point | 195.5-1970C |
---|---|
alpha | D +103.8° (c = 1.04 in dioxane) |
Boiling point | 569.0±50.0 °C(Predicted) |
Density | 1.1653 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Practically insoluble in water, freely soluble in acetone, sparingly soluble in ethanol (96 per cent). |
pka | 12.88±0.70(Predicted) |
form | Solid |
color | White to off-white |
InChIKey | CBGUOGMQLZIXBE-XGQKBEPLSA-N |
SMILES | O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,16,18,20,23,r| |
CAS DataBase Reference | 25122-46-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H360Df-H373-H413 | |||||||||
Precautionary statements | P201-P273-P308+P313 | |||||||||
Hazard Codes | Xi,T | |||||||||
Risk Statements | 36/37/38-62-53-48/20/21-61 | |||||||||
Safety Statements | 26-36-45-36/37-53 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | TU3725000 | |||||||||
HS Code | 29372290 | |||||||||
NFPA 704 |
|
Clobetasol propionate price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C8037 | Clobetasol propionate analytical standard | 25122-46-7 | 100MG | ₹6570.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1921 | Clobetasol Propionate Pharmaceutical Secondary Standard; Certified Reference Material | 25122-46-7 | 500MG | ₹23739.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C8037 | Clobetasol propionate analytical standard | 25122-46-7 | 1G | ₹34769.9 | 2022-06-14 | Buy |
TCI Chemicals (India) | C2612 | Clobetasol 17-Propionate | 25122-46-7 | 1G | ₹4200 | 2022-05-26 | Buy |
TCI Chemicals (India) | C2612 | Clobetasol 17-Propionate | 25122-46-7 | 5G | ₹10800 | 2022-05-26 | Buy |
Clobetasol propionate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Topical corticosteroid. Glucocorticoid; anti-inflammatory.
Clobetasol propionate (Cormax, Temovate, Embeline, Olux) is one of the most potent of the currently available agents and is indicated for short-term treatment of inflammatory or hyperplastic disorders. It is a synthetic fluorinated corticosteroid. It may cause a more rapid or prolonged response than other topical corticosteroids. It is recommended that clobetasol have a maximum application of 60 g/week for no longer than 14 days without occlusion and that it should not be used in children below age 12.
Indications
Clobetasol propionate (Cormax, Temovate, Embeline, Olux) is one of the most potent of the currently available agents and is indicated for short-term treatment of inflammatory or hyperplastic disorders. It is a synthetic fluorinated corticosteroid. It may cause a more rapid or prolonged response than other topical corticosteroids. It is recommended that clobetasol have a maximum application of 60 g/week for no longer than 14 days without occlusion and that it should not be used in children below age 12.
Definition
ChEBI: The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis.
Clobetasol propionate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
Halcyon Labs Pvt. Ltd | +919833750169 | Mumbai, India | 17 | 58 | Inquiry |
Enzal Chemicals India Limited | +91-9930897773 +91-9930897773 | New Delhi, India | 25 | 58 | Inquiry |
Coral Drugs Pvt Ltd | +91-1244518100 +91-8199986118 | New Delhi, India | 24 | 58 | Inquiry |
Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
Anuh Pharma Ltd (SK GROUP) | +912266227575 | Maharashtra, India | 38 | 58 | Inquiry |
Dayaram Pharma Chem | +91-9601766800 +91-9601766800 | Gujarat, India | 61 | 58 | Inquiry |
Chempifine Chemicals | +91-2225667766 +91-2225667766 | Punjab, India | 144 | 58 | Inquiry |
Stermone Chemicals Pvt Ltd | +91-9328939700 +91-9328939700 | Gujarat, India | 20 | 58 | Inquiry |
Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
Supplier | Advantage |
---|---|
GLR Innovations | 58 |
Halcyon Labs Pvt. Ltd | 58 |
Enzal Chemicals India Limited | 58 |
Coral Drugs Pvt Ltd | 58 |
Gonane Pharma | 58 |
Anuh Pharma Ltd (SK GROUP) | 58 |
Dayaram Pharma Chem | 58 |
Chempifine Chemicals | 58 |
Stermone Chemicals Pvt Ltd | 58 |
Maharshi Pharma Chem | 58 |
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