Titanocene dichloride
- CAS No.
- 1271-19-8
- Chemical Name:
- Titanocene dichloride
- Synonyms
- Cp2TiCl2;BIS(CYCLOPENTADIENYL)TITANIUM DICHLORIDE;TDC;Dichlorotitanocene;BIS(CYCLOPENTADIENYL)TITANIUM(IV) DICHLORIDE;NCI-C04502;titanium(2+);)titanium dichL;titaniumferrocene;Titanocene dichlorid
- CBNumber:
- CB3458745
- Molecular Formula:
- C10H10Cl2Ti
- Molecular Weight:
- 248.96
- MOL File:
- 1271-19-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/2/23 21:28:46
| Melting point | 260-280 °C (dec.)(lit.) |
|---|---|
| Boiling point | 355.52°C (estimate) |
| Density | 1.6 g/mL at 25 °C(lit.) |
| vapor pressure | 0.002Pa at 25℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | slightly soluble in H2O, benzene; soluble in chloroform,ethanol, toluene |
| form | crystal |
| Specific Gravity | 1.6 |
| color | red |
| Water Solubility | slow decomposition |
| Sensitive | Air & Moisture Sensitive |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| Merck | 14,9482 |
| Stability | Stable. Incompatible with strong oxidizing agents. Decomposes in water. Moisture sensitive. |
| LogP | -1.35 at 20℃ |
| CAS DataBase Reference | 1271-19-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Titanocene dichloride(1271-19-8) |
| EPA Substance Registry System | Titanocene dichloride (1271-19-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 37/38-61-40-34-33-36/37/38 | |||||||||
| Safety Statements | 36-7/8-6A-45-36/37/39-26 | |||||||||
| RIDADR | UN3261 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XR2050000 | |||||||||
| F | 8-10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29310095 | |||||||||
| Hazardous Substances Data | 1271-19-8(Hazardous Substances Data) | |||||||||
| Toxicity | Titanocene dichloride may cause skin and mucous membrane irritation. The LD50 in mice has been reported as 60 mg/kg (i.p.) and 180 mg/kg (i.v.). In the rat, the LD50 is 25 mg/kg (i.p.). | |||||||||
| NFPA 704 |
|
Titanocene dichloride price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 234826 | Bis(cyclopentadienyl)titanium(IV) dichloride 97% | 1271-19-8 | 10G | ₹2966.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 234826 | Bis(cyclopentadienyl)titanium(IV) dichloride 97% | 1271-19-8 | 50G | ₹9655.9 | 2022-06-14 | Buy |
| ALFA India | ALF-A11456-30 | Bis(cyclopentadienyl)titanium dichloride, 97% | 1271-19-8 | 250g | ₹46729 | 2022-05-26 | Buy |
| ALFA India | ALF-A11456-18 | Bis(cyclopentadienyl)titanium dichloride, 97% | 1271-19-8 | 50g | ₹9249 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T0616 | Titanocene Dichloride | 1271-19-8 | 5G | ₹2800 | 2022-05-26 | Buy |
Titanocene dichloride Chemical Properties,Uses,Production
Chemical Properties
Titanocene dichloride is a reddish-orange crystalline solid. Moderately soluble in toluene, chloroform, alcohol, and other hydroxylic solvents; sparingly soluble in water, petroleum ether, benzene, ether, carbon disulfide, and carbon tetrachloride. Stable in dry air, slowly hydrolyzed in moist air. Titanocene dichloride is irritating to the skin and mucous membranes.
Uses
Titanocene dichloride is used as an experimental cancer chemotherapeutic agent. It is used as a research chemical, as a catalyst in Ziegler–Natta polymerization reactions, and as an implant material in orthopedics, oral surgery, and neurosurgery.This metallocene is a common reagent in organometallic and organic synthesis. Titanocene dichloride is used to prepare titanocene pentasulfide. Used as an anticancer drug.
Production Methods
Titanocene dichloride is produced by the reaction of titanium tetrachloride with cyclopentadienyl sodium.
General Description
Titanocene dichloride appears as red to red-orange crystals. (NTP, 1992)
Air & Water Reactions
Stable in dry air. Decomposes in moist air and in water to form HCl .
Reactivity Profile
Titanocene dichloride is incompatible with strong oxidizers. Titanocene dichloride may decompose on exposure to water. .
Hazard
Toxic by inhalation, irritant to skin and mucous membranes.
Fire Hazard
Flash point data for Titanocene dichloride are not available; however, Titanocene dichloride is probably combustible.
Safety Profile
Poison by intravenous and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic, tumorigenic, and teratogenic data. Mutation data reported. See also TITANIUM COMPOUNDS. When heated to decomposition it emits toxic fumes of Cl-
Purification Methods
It forms bright red crystals from toluene or xylene/CHCl3 (1:1) and sublimes at 190o/2mm. It is moderately soluble in EtOH and insoluble in Et2O, *C6H6, CS2, CCl4, pet ether and H2O. The crystalline dipicrate explodes on melting at 139-140o. [Wilkinson et al. J Am Chem Soc 75 1011 1953, IR: Wilkinson & Birmingham J Am Chem Soc 76 4281 1954, NMR and X-ray: Glivicky & McCowan Can J Chem 51 2609 1973, Clearfield et al. J Am Chem Soc 53 1622 1975, Beilstein 16 IV 1769.]
Titanocene dichloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1841 | 58 | Inquiry |
| WUXI HONOR SHINE CHEMICAL CO.,LTD | +86-0510-83593312 +8619805123561 | China | 67 | 58 | Inquiry |
| Jiangsu Nengyue New Material Technology Co.,Ltd | +undefined+86-13376001577 | China | 31 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3882 | 58 | Inquiry |
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