Polysorbate 20
- CAS No.
- 9005-64-5
- Chemical Name:
- Polysorbate 20
- Synonyms
- TWEEN 20;SORBITAN MONOLAURATE;capmul;PEG-80 SORBITAN LAURATE;Polisorbate 20- PS 20;POLYSORBATE 21;POLYOXYETHYLENE SORBITAN MONOLAUREATE;POLYETHYLENE GLYCOL SORBITAN MONOLAURATE;POLYOXYETHYLENE (20) SORBITAN MONOLAURATE;Tween 20 (Trademark of ICI America, Inc.)
- CBNumber:
- CB3462544
- Molecular Formula:
- C26H50O10
- Molecular Weight:
- 522.6692
- MOL File:
- 9005-64-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/17 21:30:02
| Melting point | 98.9 °C (decomp) |
|---|---|
| Boiling point | 100 °C |
| Density | 1.11 g/mL at 20 °C |
| vapor pressure | <1.4 hPa (20 °C) |
| refractive index |
n |
| FEMA | 2915 | POLYSORBATE 20 |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 100 g/L |
| form | viscous liquid |
| Specific Gravity | 1.090～1.130 (20/20℃) |
| color | Amber |
| PH | 6-8 (50g/l, H2O, 20℃) |
| Odor | mild alcohol odor |
| PH Range | 7 |
| Odor Type | alcoholic |
| Water Solubility | 100 g/L |
| Hydrophilic-Lipophilic Balance (HLB) | 16.7 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| EPA Substance Registry System | Polysorbate 20 (9005-64-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338-P362+P364 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 22-36/37/38-37/38-41 | |||||||||
| Safety Statements | 24/25-36/37/39-36-26 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | TR7400000 | |||||||||
| F | 10-23 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 34021300 | |||||||||
| Toxicity | LD50 orally in Rabbit: 38900 mg/kg | |||||||||
| NFPA 704 |
|
Polysorbate 20 price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W291501 | Polysorbate 20 | 9005-64-5 | 1SAMPLE | ₹5272.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W291501 | Polysorbate 20 | 9005-64-5 | 1KG | ₹7026.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W291501 | Polysorbate 20 | 9005-64-5 | 10KG | ₹26706.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W291501 | Polysorbate 20 | 9005-64-5 | 25KG | ₹42379.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P9416 | TWEEN® 20 for molecular biology, viscous liquid | 9005-64-5 | 50ML | ₹3396.6 | 2022-06-14 | Buy |
Polysorbate 20 Chemical Properties,Uses,Production
Chemical Properties
Polysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a warm, somewhat bitter taste.
Uses
polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.
Definition
ChEBI: Polysorbate 20 (Tween 20) is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. It is a surfactant and emulsifier used in cleaners and personal care products.
Preparation
polysorbate 20 is prepared by condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups.
General Description
Polysorbate 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.
Health effects
Polysorbate 20 was a skin irritant in dermatitis patients but was reported not to induce irritant responses when applied to the intact skin of health volunteers. It produced, at worst, minimal irritation in the eyes of rabbits. Only a small number of cases of skin sensitization have been reported in humans, although a moderate to strong sensitizing potential was seen in guinea-pigs treated by intradermal injection.
Safety Profile
Moderately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Polysorbate 20 Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| ESTELLE CHEMICALS PVT LTD | +91-7620604545 +91-7620604545 | Maharashtra, India | 30 | 58 | Inquiry |
| VA SUDHA Chemicals Private Limited | +91-9653313056 +91-9653313056 | Maharashtra, India | 8 | 58 | Inquiry |
| HJ AROCHEM | +91-8690768060 +91-9724420086 | Ahmedabad, India | 171 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Ultra Chemical Works | +91-9820078105 +91-9820078105 | Mumbai, India | 124 | 58 | Inquiry |
| Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
| Viswaat Chemicals Limited | +91-7208827711 +91-8291300373 | Mumbai, India | 63 | 58 | Inquiry |
| Gujarat Chemicals GUJCHEM | +91-9825114095 +91-9825114095 | Gujarat, India | 42 | 58 | Inquiry |
| HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| ESTELLE CHEMICALS PVT LTD | 58 |
| VA SUDHA Chemicals Private Limited | 58 |
| HJ AROCHEM | 58 |
| JSK Chemicals | 58 |
| Ultra Chemical Works | 58 |
| Otto Chemie Pvt Ltd | 58 |
| Viswaat Chemicals Limited | 58 |
| Gujarat Chemicals GUJCHEM | 58 |
| HRV Global Life Sciences | 58 |
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