Lanolin
| Melting point | 38-40 °C |
|---|---|
| Density | 0.932-0.945 g/cm3(Temp: 15 °C) |
| Flash point | 209 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | chloroform: 0.1 g/mL, clear to faintly turbid (<29 NTU), strongly yellow-green |
| form | Adhering Crystals or Powder |
| color | White to yellow |
| Odor | Characteristic |
| Water Solubility | Soluble in ether, petroleum ether, chloroform and petroleum benzene. Sparingly soluble in ethanol. Insoluble in water. |
| Merck | 14,5358 |
| Dielectric constant | 4.2（Ambient） |
| EPA Substance Registry System | Lanolin (8006-54-0) |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WGK Germany | 1 | |||||||||
| RTECS | OE3201000 | |||||||||
| Autoignition Temperature | 833 °F | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 15050000 | |||||||||
| NFPA 704 |
|
Lanolin price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ALFA India | ALF-A16902-30 | Lanolin | 8006-54-0 | 250g | ₹4774 | 2022-05-26 | Buy |
| ALFA India | ALF-A16902-0B | Lanolin | 8006-54-0 | 1000g | ₹13029 | 2022-05-26 | Buy |
| ottokemi | L 1240 | Lanoline, anhydrous | 8006-54-0 | 500gm | ₹1287 | 2022-05-26 | Buy |
| ottokemi | L 1240 | Lanoline, anhydrous | 8006-54-0 | 5kg | ₹11061 | 2022-05-26 | Buy |
| SRL | 15932 | Lanolin anhydrous extrapure | 8006-54-0 | 500Gms | ₹2080 | 2022-05-26 | Buy |
Lanolin Chemical Properties,Uses,Production
Chemical Properties
Lanolin is a pale yellow-colored, unctuous, waxy substance with a faint, characteristic odor. Melted lanolin is a clear or almost clear, yellow liquid.
Characteristics
Lanolin is a waxy substance that sheep naturally produce to protect their wool. Because lanolin's properties are similar to those of the sebum (oil) secreted by human skin, it is a popular ingredient in moisturizers, hair care products, and soaps.
Uses
lanolin (hydrogenated) is a lanolin derivative.
Definition
lanolin: An emulsion of purified wool fat in water, containing cholesteroland certain terpene alcoholsand esters. It is used in cosmetics.
Production Methods
Lanolin is a naturally occurring wax-like material obtained from
the wool of sheep, Ovis aries Linne′ (Fam. Bovidae).
Crude lanolin is saponified with a weak alkali and the resultant
saponified fat emulsion is centrifuged to remove the aqueous phase.
The aqueous phase contains a soap solution from which, on
standing, a layer of partially purified lanolin separates. This
material is then further refined by treatment with calcium chloride,
followed by fusion with unslaked lime to dehydrate the lanolin. The
lanolin is finally extracted with acetone and the solvent is removed
by distillation.
Pharmaceutical Applications
Lanolin is widely used in topical pharmaceutical formulations and
cosmetics.
Lanolin may be used as a hydrophobic vehicle and in the
preparation of water-in-oil creams and ointments. When mixed
with suitable vegetable oils or with soft paraffin, it produces
emollient creams that penetrate the skin and hence facilitate the
absorption of drugs. Lanolin mixes with about twice its own weight
of water, without separation, to produce stable emulsions that do
not readily become rancid on storage.
Side effects
Most emollients can be used safely and effectively without side effects. However, burning, stinging, redness or irritation may occur. Rare and very serious allergic reactions are abnormal changes in the skin (e.g., whitening/softening/wetness from over-moisturisation), rashes, itching/swelling (especially on the face/tongue/throat), severe dizziness, and difficulty breathing. If any discomfort occurs, contact your doctor immediately.
Safety
Lanolin is widely used in cosmetics and a variety of topical pharmaceutical formulations.
Although generally regarded as a nontoxic and nonirritant
material, lanolin and lanolin derivatives are associated with skin
hypersensitivity reactions, and the use of lanolin in subjects with
known sensitivity should be avoided. Other reports suggest that
‘sensitivity’ arises from false positives in patch testing.However,
skin hypersensitivity is relatively uncommon; the incidence of
hypersensitivity to lanolin in the general population is estimated to
be around 5 per million.
Sensitivity is thought to be associated with the content of free
fatty alcohols present in lanolin products rather than the total
alcohol content.The safety of pesticide residues in lanolin
products has also been of concern. However, highly refined
‘hypoallergenic’ grades of lanolin and grades with low pesticide
residues are commercially available.
storage
Lanolin may gradually undergo autoxidation during storage. To inhibit this process, the inclusion of butylated hydroxytoluene is permitted as an antioxidant. Exposure to excessive or prolonged heating may cause anhydrous lanolin to darken in color and develop a strong rancidlike odor. However, lanolin may be sterilized by dry heat at 150°C. Ophthalmic ointments containing lanolin may be sterilized by filtration or by exposure to gamma irradiation.
Incompatibilities
Lanolin may contain prooxidants, which may affect the stability of certain active drugs.
Regulatory Status
Included in the FDA Inactive Ingredients Database (ophthalmic, otic, topical, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Lanolin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLO ENGINEERS | +91-9873453920 +91-9873453920 | Haryana, India | 7 | 58 | Inquiry |
| Neeru Menthol Pvt Ltd | +91-8884114465 +91-9837322285 | New Delhi, India | 70 | 58 | Inquiry |
| Unisynth Chemicals | +91-9820430673 +91-9820430673 | Maharashtra, India | 32 | 58 | Inquiry |
| Esteem Industries Pvt. Ltd. | +91-8326613321 +91-8669968881 | Mumbai, India | 85 | 58 | Inquiry |
| Gloria Interchem Pvt Ltd | +91-9825029521 +91-9825029521 | Gujarat, India | 49 | 58 | Inquiry |
| Suru Chemicals And Pharmaceuticals Pvt Ltd | +91-2267353637 +91-2267353637 | Maharashtra, India | 11 | 58 | Inquiry |
| S D Fine Chem Limited | +91-9323715856 +91-9323715856 | Maharashtra, India | 368 | 58 | Inquiry |
| Rolex Lanolin Products Limited | +91-2228512345 +91-9321660126 | Mumbai, India | 1 | 58 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLO ENGINEERS | 58 |
| Neeru Menthol Pvt Ltd | 58 |
| Unisynth Chemicals | 58 |
| Esteem Industries Pvt. Ltd. | 58 |
| Gloria Interchem Pvt Ltd | 58 |
| Suru Chemicals And Pharmaceuticals Pvt Ltd | 58 |
| S D Fine Chem Limited | 58 |
| Rolex Lanolin Products Limited | 58 |
| ALPHA CHEMIKA | 43 |
| Scientific OEM | 38 |
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