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2,4,6-Trimethylphenol

2,4,6-Trimethylphenol Structure
CAS No.
527-60-6
Chemical Name:
2,4,6-Trimethylphenol
Synonyms
Phenol, 2,4,6-trimethyl-;MESITOL;mesito;HYDROXYMESITYLENE;2-hydroxymesitylen;2-Hydroxymesitylene;2,4,6-Trimethylpenol;2,4,6-Trimetylofenol;1,3,5-trimethylphenol;2,4,6-trimethyl-pheno
CBNumber:
CB3682841
Molecular Formula:
C9H12O
Molecular Weight:
136.19
MOL File:
527-60-6.mol
MSDS File:
SDS
Modify Date:
2024/8/30 21:22:42

2,4,6-Trimethylphenol Properties

Melting point 70-72 °C(lit.)
Boiling point 220 °C(lit.)
Density 0.9809 (estimate)
vapor pressure 3.86Pa at 25℃
refractive index 1.5148 (estimate)
FEMA 4329 | 2,4,6-TRIMETHYLPHENOL
Flash point 220-221°C
storage temp. under inert gas (argon)
form Crystalline Needles
pka pK1:10.88 (25°C)
color Beige
Odor at 0.10 % in propylene glycol. mild phenolic coffee grounds
Odor Type phenolic
Water Solubility 1.008g/L(25 ºC)
JECFA Number 2013
BRN 1859675
LogP 2.73 at 25℃
CAS DataBase Reference 527-60-6(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2,4,6-trimethyl-(527-60-6)
EPA Substance Registry System 2,4,6-Trimethylphenol (527-60-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H315-H318-H335-H373-H411
Precautionary statements  P260-P273-P280-P302+P352-P305+P351+P338-P314
Hazard Codes  C,N
Risk Statements  34-51/53
Safety Statements  26-36/37/39-45-24/25-61
RIDADR  UN 2430 8/PG 3
WGK Germany  2
RTECS  OX6590000
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29071990
NFPA 704
1
3 0

2,4,6-Trimethylphenol price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T79006 2,4,6-Trimethylphenol 97% 527-60-6 25G ₹8075.45 2022-06-14 Buy
Sigma-Aldrich(India) T79006 2,4,6-Trimethylphenol 97% 527-60-6 100G ₹22223.73 2022-06-14 Buy
Sigma-Aldrich(India) 53766 2,4,6-Trimethylphenol certified reference material, TraceCERT? 527-60-6 100MG ₹9601.78 2022-06-14 Buy
TCI Chemicals (India) T0486 2,4,6-Trimethylphenol min. 98.0 % 527-60-6 25G ₹3700 2022-05-26 Buy
ALFA India ALF-A15041-36 2,4,6-Trimethylphenol, 98% 527-60-6 500g ₹18333 2022-05-26 Buy
Product number Packaging Price Buy
T79006 25G ₹8075.45 Buy
T79006 100G ₹22223.73 Buy
53766 100MG ₹9601.78 Buy
T0486 25G ₹3700 Buy
ALF-A15041-36 500g ₹18333 Buy

2,4,6-Trimethylphenol Chemical Properties,Uses,Production

Chemical Properties

BEIGE CRYSTALLINE NEEDLES

Production Methods

2,4,6-Trimethylphenol is the main product (more than 80%) of the gas phase alkylation of phenol with excess methanol (molar ratio 1 : 5) at 450 ℃ on magnesium oxide catalysts, which are doped with alkali or other metal oxides (e.g., V2O5, SrO). 2,6-Xylenol and 2,3,4,6-tetramethylphenol are the main byproducts.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 1060, 1985 DOI: 10.1021/ja00290a053
Synthetic Communications, 18, p. 1207, 1988 DOI: 10.1080/00397918808060912

Purification Methods

Crystallise the phenol from water and sublime it in vacuo. [Beilstein 6 IV 3253.]

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2,4,6-TRIMETHYLPHENOL, 1000MG, NEAT 2,4,6-TRIMETHYLPHENOL PESTANAL, 250 MG 2,4,6-TRIMETHYLPHENOL / MESITOL Benzene, 2-hydroxy-1,3,5-trimethyl 2,4,6-Trimethylphenol,99% Hydroxymesitylene Mesitol 2-hydroxymesitylen mesito 2,4,6-Trimethylpenol 2,4,6-TriMethylphenol, 99% 10GR HYDROXYMESITYLENE 1,3,5-trimethylphenol 1-Hydroxy-2,4,6-trimethylbenzene 2,4,6-trimethylofenol(polish) 2,4,6-trimethyl-pheno 2,4,6-Trimetylofenol 2-hydroxy-1,3,5-trimethyl-benzen 2-Hydroxymesitylene Trimethylphenol,98.0% 2,4,6-TRIMETHYLPHENOL 2,4,6-Trimethylphenol 527-60-6 Mesitol 527-60-6 Mesitol 2,4,6-Trimethylphenol 2,4,6-Trimethylphenol > 2,4,6-Trimethylphenol 527-60-6 Phenol, 2,4,6-trimethyl- MESITOL Bifeprunox Impurity 59 527-60-6 C9H12O1 CH33C6H2OH HOC6H2CH33 ALCOHOL Building Blocks Organic Building Blocks Phenols Oxygen Compounds Aromatic Phenols Building Blocks C9 to C20+ Chemical Synthesis Organic Building Blocks Oxygen Compounds Phenols