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H-7 DIHYDROCHLORIDE

H-7 DIHYDROCHLORIDE Structure
CAS No.
108930-17-2
Chemical Name:
H-7 DIHYDROCHLORIDE
Synonyms
H-7;H-7 DIHYDROCHLORIDE;H-7 (hydrochloride);H-7 dihydrochloride,98%;H7 dihydrochloride,H 7 dihydrochloride;Protein kinase inhibitor H-7 dihydrochloride;1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL;1-(5-isoquinolinylsulfonyl)-2-methylpiperazine 2HCl;H-7, Dihydrochloride - CAS 108930-17-2 - Calbiochem;(+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL
CBNumber:
CB3725838
Molecular Formula:
C14H19Cl2N3O2S
Molecular Weight:
364.29
MOL File:
108930-17-2.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

H-7 DIHYDROCHLORIDE Properties

Melting point 215-225 °C
storage temp. 2-8°C
solubility H2O: 20 mg/mL
form Light yellow lyophilized solid
color White to Off-White
BRN 5840763
CAS DataBase Reference 108930-17-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
F  10

H-7 DIHYDROCHLORIDE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I7016 H-7 dihydrochloride ≥98% (HPLC) 108930-17-2 5MG ₹17807.13 2022-06-14 Buy
Sigma-Aldrich(India) I7016 H-7 dihydrochloride ≥98% (HPLC) 108930-17-2 25MG ₹68489.78 2022-06-14 Buy
ALFA India ALF-J61697-MF H-7 dihydrochloride 108930-17-2 50mg ₹70428 2022-05-26 Buy
ALFA India ALF-J61697-MA H-7 dihydrochloride 108930-17-2 10mg ₹28954 2022-05-26 Buy
Product number Packaging Price Buy
I7016 5MG ₹17807.13 Buy
I7016 25MG ₹68489.78 Buy
ALF-J61697-MF 50mg ₹70428 Buy
ALF-J61697-MA 10mg ₹28954 Buy

H-7 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.

Definition

ChEBI: A hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride.

General Description

A broad-based, cell-permeable, reversible, ATP-competitive serine-threonine kinase inhibitor. Potent inhibitor of myosin light chain kinase (Ki = 97 μM), protein kinase A (Ki = 3.0 μM), protein kinase C (Ki = 6 μM), and protein kinase G (Ki = 5.8 μM). Induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells. Also inhibits telomerase activity in quercetin-, H-89-, or herbimycin A-treated NPC-076 cells.

H-7 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

H-7 DIHYDROCHLORIDE Suppliers

Global( 73)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9626 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Alfa Aesar 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58

108930-17-2(H-7 DIHYDROCHLORIDE)Related Search:

1-METHANESULFONYL-PIPERAZINE 2-Methylpiperazine PIPERAZINE DIHYDROCHLORIDE 1-BENZENESULFONYL-PIPERAZINE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
1,4-BIS[3-(3,4,5-TRIMETHOXYBENZOYLOXY)PROPYL]HOMOPIPERAZINE DIHYDROCHLORIDE 1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE 1-(3-TRIFLUOROMETHYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE 1,4-BUTANEDIAMINE DIHYDROCHLORIDE 1-(3-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE
1,3-PROPANEDIAMINE DIHYDROCHLORIDE 1,4'-BIPIPERIDINE DIHYDROCHLORIDE,[1,4']BIPIPERIDINYL DIHYDROCHLORIDE 1,4-BENZENEDIAMINE DIHYDROCHLORIDE [1,4']BIPIPERIDINYL DIHYDROCHLORIDE 10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE,1-(3-Methylphenyl)piperazine dihydrochloride 1-(4-Bromophenyl)piperazine 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
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H-7 DIHYDROCHLORIDE H-7 (+/-)-1-(5-ISOQUINOLINESULPHONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE (+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL (-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, DI-HCL SALT (+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine 2HCl H-7 dihydrochloride,98% Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride 5-[(2-Methyl-1-piperazinyl)sulfonyl]isoquinoline Hydrochloride H-7, Dihydrochloride - CAS 108930-17-2 - Calbiochem H-7 (hydrochloride) H7 dihydrochloride,H 7 dihydrochloride 5-((2-Methylpiperazin-1-yl)sulfonyl)isoquinoline dihydrochloride Protein kinase inhibitor H-7 dihydrochloride 108930-17-2 C14H19Cl2N3O2S Cell Biology Serine/Threonine Kinase Inhibitors Kinase/Phosphatase Biology Protein kinase A and protein kinase C (PKA and PKC) BioChemical Cell Signaling and Neuroscience Protein Kinase Inhibitors and Activators