4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE Structure
CAS No.
4233-33-4
Chemical Name:
4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE
Synonyms
PTAD;4-PHENYL-3;AURORA KA-3851;Mosapride Impurity 24;4-Phenyl-1,2,4-triazole-3,5-dione;4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE;4-phenyl-1,2,4-triazole-3,5-quinone;4-Phenyl-1,2,3-triazoline-3,5-dione;4-Phenyl-4H-1,2,4-triazole-3,5-dione;4-PHENYL-3H-1,2,4-TRIAZOLINE-3,5-DIONE
CBNumber:
CB3769656
Molecular Formula:
C8H5N3O2
Molecular Weight:
175.14
MOL File:
4233-33-4.mol
MSDS File:
SDS
Modify Date:
2024/4/12 23:00:59

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE Properties

Melting point 165-170 °C (dec.)(lit.)
Boiling point 263.8±23.0 °C(Predicted)
Density 1.47±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka -1.71±0.20(Predicted)
color Red to Dark Red
BRN 141548
InChIKey ISULLEUFOQSBGY-UHFFFAOYSA-N
CAS DataBase Reference 4233-33-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
HS Code  29339900

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 280992 4-Phenyl-1,2,4-triazoline-3,5-dione 97% 4233-33-4 1G ₹10825 2022-06-14 Buy
Sigma-Aldrich(India) 280992 4-Phenyl-1,2,4-triazoline-3,5-dione 97% 4233-33-4 5G ₹31977.05 2022-06-14 Buy
TCI Chemicals (India) P1184 4-Phenyl-1,2,4-triazoline-3,5-dione 4233-33-4 1G ₹9700 2022-05-26 Buy
TCI Chemicals (India) P1184 4-Phenyl-1,2,4-triazoline-3,5-dione 4233-33-4 5G ₹17800 2022-05-26 Buy
TCI Chemicals (India) P1184 4-Phenyl-1,2,4-triazoline-3,5-dione 4233-33-4 25G ₹22600 2022-05-26 Buy
Product number Packaging Price Buy
280992 1G ₹10825 Buy
280992 5G ₹31977.05 Buy
P1184 1G ₹9700 Buy
P1184 5G ₹17800 Buy
P1184 25G ₹22600 Buy

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE Chemical Properties,Uses,Production

Chemical Properties

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE is Red Solid

Uses

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE is used in the methods for determining levels of 1,25 dihydroxyvitamin d2 and d3 in biological and food samples and dietary supplements.

General Description

4-Phenyl-1,2,4-triazoline-3,5-dione, also known as Cookson reagent, is a strong dienophile, which gives a stable Diels-Alder adduct quantitatively within a short time and under mild conditions. It is commonly used as a protecting group of the diene moiety for the synthesis of vitamin D3 (VD3)-related compounds.

Purification Methods

PTAD forms carmine red needles by sublimation (ice cold finger) at 100o/0.1mm, and/or by recrystallisation from EtOH. IR: 1760 and 1780 cm-1 . [Cookson et al. Org Synth 51 121 1971, Moore max et al. J Org Chem 39 3700 1974, Beilstein 26 I 57, 26 III/IV 540.]

4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE Preparation Products And Raw materials

Global( 150)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16209 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29900 58 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 2417 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
AURORA KA-3851 4-PHENYL-3H-1,2,4-TRIAZOLINE-3,5-DIONE 4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE 4-PHENYL-3,5-DIHYDRO-4ETA-1,2,4-TRIAZOLE-3,5-DIONE 4-Phenyl-1,2,4-triazole-3,5-dione 3H-1,2,4-Triazole-3,5(4H)-dione, 4-phenyl- 3,5-DIHYDRO-4-PHENYL-4H-1,2,4-TRIAZOLE-3,5-DIONE 97+% 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, PTAD 4-Phenyl-3,5-dihydro-4H-1,2,4-triazole-3,5-dione 4-Phenyl-4H-1,2,4-triazole-3,5-dione 4-phenyl-1,2,4-triazole-3,5-quinone 4-Phenyl-1,2,3-triazoline-3,5-dione 3,5-DIHYDRO-4-PHENYL-4H-1,2,4-TRIAZOLE-3 3,5-DIHYDRO-4-PHENYL-4ETA-1,2,4-TRIAZOLE-3,5-DIONE 3,5-DIHYDRO-4-PHENYL-4H-1,2,4-TRIAZOLE-3,5-DIONE 4-Phenyl-1,2,4-triazoline-3,5-dione 97% 3,5-Dihydro-4-phenyl-4H-1,2,4-triazole-3,5-dione for synthesis 4-PHENYL-3 PTAD Mosapride Impurity 24 4233-33-4 Building Blocks Heterocyclic Building Blocks Triazoles Amino Acids & Derivatives Aromatics Heterocycles