2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE
![2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Structure](CAS/GIF/526-36-3.gif)
- CAS No.
- 526-36-3
- Chemical Name:
- 2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE
- Synonyms
- Otrix;Otriven;Otrivin;Ba-11391;Otrivine;Rhinoxilin;XYLOMETAZOLINE;Xylomethazoline;AKOS BBS-00000259;XYLOMETAZOLINEANDITSHYDROCHLORIDE
- CBNumber:
- CB0759137
- Molecular Formula:
- C16H24N2
- Molecular Weight:
- 244.38
- MOL File:
- 526-36-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/21 10:59:17
Melting point | 131-133° |
---|---|
Boiling point | 394.2±21.0 °C(Predicted) |
Density | 1.00±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO: 49 mg/mL (200.51 mM);Ethanol: 49 mg/mL (200.51 mM) |
pka | pKa 10.6±0.1(H2O t = 22.0) (Uncertain) |
Water Solubility | Water: Insoluble |
CAS DataBase Reference | 526-36-3 |
2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Chemical Properties,Uses,Production
Uses
Adrenergic (vasoconstrictor).
brand name
Neo-Synephrine II (Sterling Winthrop); Otrivin Hydrochloride (Ciba-Geigy).
Synthesis
Xylometazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline (11.1.40), is also synthesized in a single reaction by cyclocondensation of 4-tert-butyl-2,6- dimethylbenzylcyanide with ethylendiamine [43,44].
2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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526-36-3(2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE)Related Search:
(r)-budesonide
2-(4-tert-Butyl-3-hydroxy-2,6-dimethylphenyl)acetic acid
Oxymetazoline hydrochloride EP impurity A
4-tert-Butyl-2,6-dimethyl-3-hydroxyphenylacetamide
(Oxymetazoline hydrochloride impurity)
4-TERT-BUTYL-3-HYDROXY-2,6-DIMETHYLPHENYLACETONITRILE
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XYLOMETAZOLINE
2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE
AKOS BBS-00000259
XYLOMETAZOLINEANDITSHYDROCHLORIDE
Xylometazoline (base and/or unspecified salts)
1h-imidazole,2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydr
2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazolin
2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline
2-[[4-(1,1-Dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1H-imidazole
2-Imidazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-
Ba-11391
Otriven
Otrivin
Otrivine
Otrix
Xylomethazoline
1H-Imidazole,2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-
ORGANIC CHEMICAL - XYLOMETAZOLINE HYDROCHLOROTHIAZIDE
Oxymetazoline Impurity 2(Oxymetazoline EP Impurity B)
2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole
2-(4-TERT-BUTYL-2,6-DIMETHYL-BENZYL)-4,5-DIHYDRO-1H-IMIDAZOLE USP/EP/BP
Rhinoxilin
2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1h-imidazole(xylometazoline),
526-36-3