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RO 08-2750

RO 08-2750 Structure
CAS No.
37854-59-4
Chemical Name:
RO 08-2750
Synonyms
RO 08-2750;7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE;7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde;2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde;Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-;growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI
CBNumber:
CB3844689
Molecular Formula:
C13H10N4O3
Molecular Weight:
270.24
MOL File:
37854-59-4.mol
Modify Date:
2023/6/30 15:45:59
Request For Quotation

RO 08-2750 Properties

storage temp. Store at -20°C
solubility ≤2.7mg/ml in DMSO
form solid
color Orange

RO 08-2750 Chemical Properties,Uses,Production

Uses

Ro 08-2750 is a TrkA inhibitor and NGF-induced apoptosis inhibitor.

Biological Activity

Non-peptide inhibitor of NGF that binds the NGF dimer (K D ~ 1 μ M) possibly causing a conformational change. Inhibits binding selectively to p75 NTR at submicromolar concentrations and to both p75 NTR and TrkA at higher concentrations (> 5 μ M). Prevents NGF-induced apoptosis in SK-N-MC cells.

RO 08-2750 Preparation Products And Raw materials

Raw materials

Preparation Products

RO 08-2750 Suppliers

Global( 37)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
InvivoChem 13549236410 China 6755 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24647 58 Inquiry
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 China 10010 58 Inquiry
Changzhou PBpharmaceutical R&D Co.,Ltd 0519-83990708 China 476 55 Inquiry
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 China 2380 58 Inquiry
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 China 3466 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58
InvivoChem 58
Aladdin Scientific 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Henan Alpha Chemical Co., Ltd. 58
Changzhou PBpharmaceutical R&D Co.,Ltd 55
Kaifeng Mingren Pharmaceutical Co.,LTD 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58

37854-59-4(RO 08-2750)Related Search:

G-749 GW441756 Eg LUMIFLAVINE RO 08-2750
2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde 7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE RO 08-2750 Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo- growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI 7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde 37854-59-4