ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >protein tyrosine kinase >GW441756

GW441756

CAS No.: 504433-23-2

Chemical Name:: GW441756

Synonyms: Gw;CS-1085;W 441756;GW441758;GW 441756;GW441756, >98%;GW441756 USP/EP/BP;GW 441756; GW-441756;3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one;-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one

CBNumber:: CB1839809

Molecular Formula:: C17H13N3O

Molecular Weight:: 275.3

MOL File:: 504433-23-2.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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GW441756 Properties

Boiling point	568.0±50.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	Store at RT
solubility	Soluble in DMSO (up to 5 mg/ml).
pka	11.04±0.20(Predicted)
form	solid
color	Orange
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

NFPA 704

	0
2		0

GW441756 Chemical Properties,Uses,Production

Uses

GW 441756 is an effective Trk binder, a novel bioactive molecule used in the treatment of neuroblastoma in infants.

Biological Activity

Potent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC 50 = 2 nM). Displays > 100-fold selectivity over a range of other kinases.

GW441756 Preparation Products And Raw materials

Raw materials

Preparation Products

GW441756 Suppliers

Global( 125)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	+86-86-22-87899925 +86-8618522618860	China	694	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24639	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	58
Dideu Industries Group Limited	58

GW441756 Spectrum

GW441756(504433-23-2)¹HNMR

504433-23-2(GW441756)Related Search:

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GW 284543 hydrochloride - UNC 10225170 hydrochloride 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine GW9508 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- 1756-L71

1756-OF4 GW441756 1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

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1,3-DIHYDRO-3-[(1-METHYL-1H-INDOL-3-YL)METHYLENE]-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE GW 441756 Gw 2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]- (Z)-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one -3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one 3-[(1-METHYLINDOL-3-YL)METHYLIDENE]-1H-PYRROLO[3,2-B]PYRIDIN-2-ONE;HYDROCHLORIDE GW 441756; GW-441756 CS-1085 GW441756, >98% W 441756 GW441756 USP/EP/BP 3-((1-methyl-1H-indol-3-yl)methylene)-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one GW441758 504433-23-2 504433-23-3 Angiogenesis and Metastasis Inhibitors