ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Nuclear transcription factor (NF-κB) >NF-κB inhibitor >6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE Structure
CAS No.
545380-34-5
Chemical Name:
6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
Synonyms
QNZ;CS-902;EVP4593;EVP-4593;EVP 4593;CAY10470;QNZ (EVP4593);CAY10470|||EVP4593;QNZ (EVP4593);EVP-4593;NF-κB Activation Inhibitor
CBNumber:
CB7500822
Molecular Formula:
C22H20N4O
Molecular Weight:
356.42
MOL File:
545380-34-5.mol
MSDS File:
SDS
Modify Date:
2023/8/29 17:14:30

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE Properties

Melting point 169-175°C
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO: soluble15mg/mL, clear
form powder
color white to beige
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H410
Precautionary statements  P264-P270-P301+P312-P330-P501-P273-P391-P501
WGK Germany  3

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0579 EVP4593 ≥98% (HPLC) 545380-34-5 5MG ₹15795.3 2022-06-14 Buy
Sigma-Aldrich(India) SML0579 EVP4593 ≥98% (HPLC) 545380-34-5 25MG ₹64224.6 2022-06-14 Buy
Sigma-Aldrich(India) 481406 NF-κB Activation Inhibitor - CAS 545380-34-5 - Calbiochem The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is pri 545380-34-5 1MG ₹16250.01 2022-06-14 Buy
Product number Packaging Price Buy
SML0579 5MG ₹15795.3 Buy
SML0579 25MG ₹64224.6 Buy
481406 1MG ₹16250.01 Buy

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-a production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1m

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 125)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26165 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE Spectrum

QNZ EVP 4593 EVP4593 EVP-4593 4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]- 4-N-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediaMine QNZ (EVP4593) QNZ (EVP4593);EVP-4593 N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine NF-κB Activation Inhibitor EVP4593; EVP 4593; EVP-4593 CS-902 NF-κB Activation Inhibitor - CAS 545380-34-5 - Calbiochem 6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLIN CAY10470 6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE USP/EP/BP 6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUI N4- [2- (4-phenoxyphenyl) ethyl] -4,6-neneneba quinazoline diamine CAY10470|||EVP4593 545380-34-5 C22H20N4O Inhibitors Amines Aromatics Heterocycles All Inhibitors NF-kB