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WITHAFERIN A

WITHAFERIN A Structure
CAS No.
5119-48-2
Chemical Name:
WITHAFERIN A
Synonyms
NSC 273757;nsc-101088;upeferinA.;Withaferine;WITHAFERIN A;withaferinea;Withaferin A Standard;Withaferin A 5119-48-2;delta-lactone,(20s,22r)-oxo;Withaferin A from leaves of Withania somnifera
CBNumber:
CB9454365
Molecular Formula:
C28H38O6
Molecular Weight:
470.6
MOL File:
5119-48-2.mol
MSDS File:
SDS
Modify Date:
2024/4/17 18:50:11

WITHAFERIN A Properties

Melting point 252-253℃
alpha D28 +125° (c = 1.30 in CHCl3)
Boiling point 680.7±55.0 °C(Predicted)
Density 1.28
Flash point 226℃
storage temp. Desiccate at -20°C
solubility Soluble in DMSO (up to 20 mg/ml)
pka 13.49±0.70(Predicted)
form White solid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey DBRXOUCRJQVYJQ-CKNDUULBSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  T
WGK Germany  3
RTECS  KE7288500
HS Code  29322090

WITHAFERIN A price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W4394 Withaferin A ≥95% (HPLC) 5119-48-2 5MG ₹52533.73 2022-06-14 Buy
Sigma-Aldrich(India) 89910 Withaferin A analytical standard 5119-48-2 10MG ₹62081.38 2022-06-14 Buy
Sigma-Aldrich(India) 681535 Withaferin A, Withania somnifera - CAS 5119-48-2 - Calbiochem A cell-permeable steroidal lactone that displays antitumor, anti-inflammatory, radiosensitizing, and immunosuppressive properties. 5119-48-2 1MG ₹18400 2022-06-14 Buy
Sigma-Aldrich(India) 681535 Withaferin A, Withania somnifera - CAS 5119-48-2 - Calbiochem A cell-permeable steroidal lactone that displays antitumor, anti-inflammatory, radiosensitizing, and immunosuppressive properties. 5119-48-2 5MG ₹47800 2022-06-14 Buy
Product number Packaging Price Buy
W4394 5MG ₹52533.73 Buy
89910 10MG ₹62081.38 Buy
681535 1MG ₹18400 Buy
681535 5MG ₹47800 Buy

WITHAFERIN A Chemical Properties,Uses,Production

Chemical Properties

Solid

Definition

ChEBI: A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Phys lis longifolia, it exhibits cytotoxic activity.

Biological Activity

Steroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) spouting in vitro (IC 50 = 12 nM) and in vivo . Prevents NF- κ B activation by inhibiting activation of IKK β . Also inhibits chymotrypsin-like activity of the 20S proteasome.

WITHAFERIN A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 133)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Natural Remedies Pvt Ltd +91 (80) 4020-9999 New Delhi, India 110 50 Inquiry
Natucare India 08048372644Ext 102 Mumbai, India 8 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Biosyn Research Chemicals +91 9346022300/+91 9399339999 Telangana, India 1340 58 Inquiry
BINBO BIOLOGICAL CO.,LTD +8618629063126 China 346 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +86-28-82633860 +86-18080483897 China 3424 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 4088 58 Inquiry

WITHAFERIN A Spectrum

WITHAFERIN A 5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-5-beta-ergosta-24-dien-26-oicacid delta-lactone,(20s,22r)-oxo nsc-101088 (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oicacidδ-lactone NSC 273757 Withaferine (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta- 2,24-dien-26-oic Acid δ-Lactone Withaferin A NSC 273757 NSC 101088 5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide withaferinea Withaferin A from leaves of Withania somnifera Ergosta-2,24-dien-26-oicacid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, d-lactone, (4b,5b,6b,22R)- Withaferin A, Withania somnifera - CAS 5119-48-2 - Calbiochem Withaferin A 5119-48-2 Withaferin A Standard Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, δ-lactone, (4β,5β,6β,22R)- AshwagandhaQ: What is Ashwagandha Q: What is the CAS Number of Ashwagandha Q: What is the storage condition of Ashwagandha (4beta,5beta,6beta,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione upeferinA. 5119-48-2 Intermediates & Fine Chemicals Pharmaceuticals Steroids antibiotic