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metiazinic acid

metiazinic acid Structure
CAS No.
13993-65-2
Chemical Name:
metiazinic acid
Synonyms
Metian;Soripal;RP 16091;Ambrunate;Novartril;Soridermal;Metiazinic;metiazinic acid;(10-METHYL2-PHENOTHIAZINYL)ACETICACID;10H-Phenothiazine-2-acetic acid, 10-methyl-
CBNumber:
CB3889277
Molecular Formula:
C15H13NO2S
Molecular Weight:
271.33
MOL File:
13993-65-2.mol
Modify Date:
2023/4/23 13:52:06
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metiazinic acid Properties

Melting point 146℃
Boiling point 482.6±44.0 °C(Predicted)
Density 1.2237 (rough estimate)
refractive index 1.7500 (estimate)
pka 4.12±0.10(Predicted)
Water Solubility 31mg/L(30 ºC)

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice, rats (mg/kg): 800, ~500 orally (Joulou)

metiazinic acid Chemical Properties,Uses,Production

Definition

ChEBI: Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.

Trade name

Roimal (Kantoishi, Japan), Soripal (Torii, Japan).

Synthesis

Metiazinic acid is prepared via the Willgerodt reaction (sulfur and morpholine) from 2-acetyl-10-methylphenothiazine.
Synthesis of metiazinic acid

Dosage

Metiazinic acid has been beneficial to arthritis patients when given at a daily dose of 0.75 – 1.5 g/d.

metiazinic acid Preparation Products And Raw materials

Raw materials

Morpholine Potassium hydroxide Sulfur

Preparation Products

metiazinic acid Suppliers

Global( 5)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
AK Scientific, Inc. 650 494 8666 United States 6357 65 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Specs +31 15 251 8111 The Netherlands 6835 70 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
AK Scientific, Inc. 65
Lanospharma Laboratories Co.,Ltd 56
Specs 70
TargetMol Chemicals Inc. 58

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metiazinic acid Metiazinic (10-METHYL2-PHENOTHIAZINYL)ACETICACID Ambrunate Metian Novartril RP 16091 Soridermal Soripal (10-methyl-10H-phenothiazin-2-yl)acetic acid 10H-Phenothiazine-2-acetic acid, 10-methyl- 13993-65-2