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trimetaphan camsilate

trimetaphan camsilate Structure
CAS No.
68-91-7
Chemical Name:
trimetaphan camsilate
Synonyms
NU-2222;Arfonad;Arphonad;Ro 2-2222;MethioplegiuM;Trimetaphan camsylate;trimetaphan camsilate;TriMetaphan caMphorsulfonate;Trimethaphan camphorsulfonate;TRIMETHAPHANCAMPHORSULPHONATE
CBNumber:
CB3917983
Molecular Formula:
C22H25N2OS.C10H16O4S
Molecular Weight:
597.817
MOL File:
68-91-7.mol
Modify Date:
2024/10/28 23:16:16

trimetaphan camsilate Properties

Melting point 245 °C (decomp)
alpha D20 +22.0° (c = 4 in water)

trimetaphan camsilate Chemical Properties,Uses,Production

Definition

ChEBI: The (S)-camphorsulfonate salt of trimethaphan.

General Description

Trimethaphan camsylate,(+)-1,3-dibenzyldecahydro2-oxoimidazo[4,5-c]thieno[1,2-α]-thiolium 2-oxo-10-bornanesulfonate (1:1)(Arfonad), consists of white crystals or a crystalline powderwith a bitter taste and a slight odor. It is soluble inwater and alcohol but only slightly soluble in acetone andether. The pH of a 1% aqueous solution is 5.0 to 6.0.

Clinical Use

This ganglionic blocking agent is short acting and isused for certain neurosurgical procedures in which excessivebleeding obscures the operative field. Certain craniotomiesare included among these operations. The actionof the drug is direct vasodilation, and because of its transientaction, it is subject to minute-by-minute control.This fleeting action, however, makes it useless for hypertensivecontrol. The drug is ineffective when given orally.The usual route of administration is intravenous.Trimethaphan camsylate is indicated in the treatment ofhypertensive emergencies to reduce blood pressure rapidly.These emergencies may include pulmonary hypertensionassociated with systemic hypertension and acutedissecting aneurysm.

trimetaphan camsilate Preparation Products And Raw materials

Raw materials

Preparation Products

trimetaphan camsilate Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 7724 58 Inquiry
TargetMol Chemicals Inc. +8613564774135 United States 19863 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 19711 58 Inquiry
Jiangxi Baicao Pharmaceutical Co., Ltd., +86-0796-8118889-8030 +86-15907062626 China 113 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9983 58 Inquiry
3B Scientific Corporation 847.281.9822 United States 6718 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6137 39 Inquiry
Leancare Ltd. +33 962096793 United Kingdom 6446 42 Inquiry
United States Biological 1-800-520-3011 United States 6075 58 Inquiry
Arphonad MethioplegiuM Ro 2-2222 TriMetaphan caMphorsulfonate TriMethaphan 10-caMphorsulfonate trimetaphan camsilate Trimetaphan camsylate TRIMETHAPHANCAMPHORSULPHONATE Trimethaphan camphorsulfonate Arfonad NU-2222 trimetaphan camsilate USP/EP/BP 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,2-b]imidazol-5-ium-2-one:[(1R,4S)-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonate 68-91-7 C32H40N2O5S2 C22H25N2OSC10H15O4S