trimetaphan camsilate
- CAS No.
- 68-91-7
- Chemical Name:
- trimetaphan camsilate
- Synonyms
- NU-2222;Arfonad;Arphonad;Ro 2-2222;MethioplegiuM;Trimetaphan camsylate;trimetaphan camsilate;TriMetaphan caMphorsulfonate;Trimethaphan camphorsulfonate;TRIMETHAPHANCAMPHORSULPHONATE
- CBNumber:
- CB3917983
- Molecular Formula:
- C22H25N2OS.C10H16O4S
- Molecular Weight:
- 597.817
- MOL File:
- 68-91-7.mol
- Modify Date:
- 2024/10/28 23:16:16
trimetaphan camsilate Chemical Properties,Uses,Production
Definition
ChEBI: The (S)-camphorsulfonate salt of trimethaphan.
General Description
Trimethaphan camsylate,(+)-1,3-dibenzyldecahydro2-oxoimidazo[4,5-c]thieno[1,2-α]-thiolium 2-oxo-10-bornanesulfonate (1:1)(Arfonad), consists of white crystals or a crystalline powderwith a bitter taste and a slight odor. It is soluble inwater and alcohol but only slightly soluble in acetone andether. The pH of a 1% aqueous solution is 5.0 to 6.0.
Clinical Use
This ganglionic blocking agent is short acting and isused for certain neurosurgical procedures in which excessivebleeding obscures the operative field. Certain craniotomiesare included among these operations. The actionof the drug is direct vasodilation, and because of its transientaction, it is subject to minute-by-minute control.This fleeting action, however, makes it useless for hypertensivecontrol. The drug is ineffective when given orally.The usual route of administration is intravenous.Trimethaphan camsylate is indicated in the treatment ofhypertensive emergencies to reduce blood pressure rapidly.These emergencies may include pulmonary hypertensionassociated with systemic hypertension and acutedissecting aneurysm.
trimetaphan camsilate Preparation Products And Raw materials
Raw materials
Preparation Products
trimetaphan camsilate Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 7724 | 58 | Inquiry |
TargetMol Chemicals Inc. | +8613564774135 | United States | 19863 | 58 | Inquiry |
TargetMol Chemicals Inc. | 15002134094 | China | 19711 | 58 | Inquiry |
Jiangxi Baicao Pharmaceutical Co., Ltd., | +86-0796-8118889-8030 +86-15907062626 | China | 113 | 58 | Inquiry |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | China | 9983 | 58 | Inquiry |
3B Scientific Corporation | 847.281.9822 | United States | 6718 | 47 | Inquiry |
2A PharmaChem USA | (630) 737-0988 | United States | 6137 | 39 | Inquiry |
Leancare Ltd. | +33 962096793 | United Kingdom | 6446 | 42 | Inquiry |
United States Biological | 1-800-520-3011 | United States | 6075 | 58 | Inquiry |