Ranitidinebismuthcitrate

Ranitidinebismuthcitrate Structure
CAS No.
128345-62-0
Chemical Name:
Ranitidinebismuthcitrate
Synonyms
Pylorid;Gastrimuto;Ranitidine bismutrex;RANTIDINEBISMUTHCITRATE;TIANFU CHEM-- Ranitidinebismuthcitrate;2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
CBNumber:
CB41073641
Molecular Formula:
C19H30N4O10S
Molecular Weight:
506.53
MOL File:
128345-62-0.mol
MSDS File:
SDS
Modify Date:
2024/3/19 15:37:50

Ranitidinebismuthcitrate Chemical Properties,Uses,Production

Description

Ranitidine bismuth citrate, a novel salt formed from ranitidine and a bismuth citrate complex, is a new agent introduced in the United Kingdom for the treatment of duodenal and benign gastric ulcers, for eradication of Helicobacfer pylori, and for prevention of relapse of duodenal ulcer when administered in combination with an antibiotic such as clarithromycin or amoxicillin. Ranitidine is a potent histamine H2-receptor antagonist with ability to inhibit gastric acid secretion. Other type of agents such as tripotassium dicitrato bismuthate exert their therapeutic effects in peptic ulceration by providing a protective coating to the ulcer crater, stimulating endogenous prostaglandin production, and inhibiting pepsin activity. More significantly, they inhibit micro-organism Helicobacfer pylori, a prevalent, specifically human pathogen associated with gastritis and gastric ulcers. The title compound possesses a novel combination of properties of the above two types of drugs and displays excellent therapeutic efficacy in clinical studies. Ranitidine bismuth citrate is being investigated for use in gastritis and non-ulcerating dyspepsia, acute healing of gastrointestinal ulcer and in prevention of the recurrence of peptic ulcer disease.

Uses

Antagonist (to histamine H2receptors).

Hazard

A poison by ingestion.

Ranitidinebismuthcitrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Monopoly Innovations Pvt. Ltd. +undefined-9321425897 +undefined-9819745149 Maharashtra, India 45 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
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Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Hebei Duling International Trade Co. LTD +8617333973358 China 15438 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
DONBOO AMINO ACID COMPANY +8613063595538 China 9365 58 Inquiry
Pylorid Ranitidine bismutrex 2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine Gastrimuto RANTIDINEBISMUTHCITRATE TIANFU CHEM-- Ranitidinebismuthcitrate 128345-62-0 C13H22N4O3SC6H5O7Bi