Ranitidinebismuthcitrate

Ranitidinebismuthcitrate Structure
CAS No.
128345-62-0
Chemical Name:
Ranitidinebismuthcitrate
Synonyms
Pylorid;Gastrimuto;Ranitidine bismutrex;RANTIDINEBISMUTHCITRATE;TIANFU CHEM-- Ranitidinebismuthcitrate;2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
CBNumber:
CB41073641
Molecular Formula:
C19H30N4O10S
Molecular Weight:
506.53
MOL File:
128345-62-0.mol
MSDS File:
SDS
Modify Date:
2024/10/28 23:16:16

Ranitidinebismuthcitrate Chemical Properties,Uses,Production

Description

Ranitidine bismuth citrate, a novel salt formed from ranitidine and a bismuth citrate complex, is a new agent introduced in the United Kingdom for the treatment of duodenal and benign gastric ulcers, for eradication of Helicobacfer pylori, and for prevention of relapse of duodenal ulcer when administered in combination with an antibiotic such as clarithromycin or amoxicillin. Ranitidine is a potent histamine H2-receptor antagonist with ability to inhibit gastric acid secretion. Other type of agents such as tripotassium dicitrato bismuthate exert their therapeutic effects in peptic ulceration by providing a protective coating to the ulcer crater, stimulating endogenous prostaglandin production, and inhibiting pepsin activity. More significantly, they inhibit micro-organism Helicobacfer pylori, a prevalent, specifically human pathogen associated with gastritis and gastric ulcers. The title compound possesses a novel combination of properties of the above two types of drugs and displays excellent therapeutic efficacy in clinical studies. Ranitidine bismuth citrate is being investigated for use in gastritis and non-ulcerating dyspepsia, acute healing of gastrointestinal ulcer and in prevention of the recurrence of peptic ulcer disease.

Uses

Antagonist (to histamine H2receptors).

Hazard

A poison by ingestion.

Ranitidinebismuthcitrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 66)Suppliers
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Monopoly Innovations Pvt. Ltd. +undefined-9321425897 +undefined-9819745149 Maharashtra, India 45 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21628 55 Inquiry
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TargetMol Chemicals Inc. +8613564774135 United States 19881 58 Inquiry
Pylorid Ranitidine bismutrex 2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine Gastrimuto RANTIDINEBISMUTHCITRATE TIANFU CHEM-- Ranitidinebismuthcitrate 128345-62-0 C13H22N4O3SC6H5O7Bi