HEXAHYDROCURCUMIN
- CAS No.
- 36062-05-2
- Chemical Name:
- HEXAHYDROCURCUMIN
- Synonyms
- HEXAHYDROCURCUMIN;Hexahydrocurcumin, BR;5-dimethyl ether Gallic Acid;5-dimethoxy-4-hydroxy Benzoic Acid;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one;1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone;3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-;(RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;5-Hydroxy-1-(4-hydroxy-3-Methoxycyclohexyl)-7-(4-hydroxy-3-Methoxyphenyl)heptan-3-one
- CBNumber:
- CB41412369
- Molecular Formula:
- C21H26O6
- Molecular Weight:
- 374.43
- MOL File:
- 36062-05-2.mol
- Modify Date:
- 2024/7/2 8:55:07
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
HEXAHYDROCURCUMIN Chemical Properties,Uses,Production
Description
Hexahydrocurcumin is a natural product and glucuronide metabolite of curcumin that has anti-inflammatory, antioxidant, and anticancer properties. It reduces prostaglandin E2 (PGE2) production stimulated by phorbol 12-myristate 13-acetate (PMA; ) by 37% in human colonic epithelial cells when used at a concentration of 20 μM. Hexahydrocurcumin (3.125-25 μM) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner. It does not affect LPS-induced cytokine release but inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation when used at a concentration of 50 μM. Hexahydrocurcumin prevents the formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer and potentiates the effect of 5-fluorouracil .
Uses
Hexahydrocurcumin is an intermediate in the synthesis of Gingerenone A (G387500) which is an antifungal and antiparasitic diarylheptenone that is isolated from Zingiber officinale (more commonly known as ginger), a medicinal plant that is used to treat inflammation and musculoskeletal disorders.
HEXAHYDROCURCUMIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Natural Remedies Pvt Ltd | +91 (80) 4020-9999 | New Delhi, India | 110 | 50 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 6938 | 58 | Inquiry |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | China | 19994 | 58 | Inquiry |
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | China | 258 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | China | 9425 | 58 | Inquiry |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | China | 19947 | 58 | Inquiry |
36062-05-2(HEXAHYDROCURCUMIN)Related Search:
1of3
chevron_right