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BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE Structure
CAS No.
33171-05-0
Chemical Name:
BIS(4-HYDROXYCINNAMOYL)METHANE
Synonyms
BISDEMETHOXY CURCUMIN;CURCUMIN 3;Misdemeanour;Didemethoxycurcumin;BIS-DESMETHOXYCURCUMIN;DEMETHOXYCURCUMIN, BIS-;Bisdemethoxycurcumin(b);(E,E)-BisdeMethoxycurcuMin;Bisdemethoxycurcumin(BDMC);Bis(p-hydroxycinnamoyl)methane
CBNumber:
CB9180475
Molecular Formula:
C19H16O4
Molecular Weight:
308.33
MOL File:
33171-05-0.mol
Modify Date:
2024/4/2 16:26:50

BIS(4-HYDROXYCINNAMOYL)METHANE Properties

Melting point 221-223 ºC
Boiling point 551.3±45.0 °C(Predicted)
Density 1.285
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 8.50±0.46(Predicted)
form solid
color Orange to Dark Orange
BRN 3149384
Stability Light Sensitive
LogP 3.155 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  29145090
NFPA 704
0
2 0

BIS(4-HYDROXYCINNAMOYL)METHANE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B6938 Bisdemethoxycurcumin ≥98% (HPLC), solid 33171-05-0 5MG ₹12329.68 2022-06-14 Buy
Sigma-Aldrich(India) PHR3434 Bisdesmethoxycurcumin certified reference material, pharmaceutical secondary standard 33171-05-0 50MG ₹19863.88 2022-06-14 Buy
Sigma-Aldrich(India) B6938 Bisdemethoxycurcumin ≥98% (HPLC), solid 33171-05-0 25MG ₹48106.3 2022-06-14 Buy
Sigma-Aldrich(India) 90594 Bisdemethoxycurcumin analytical standard 33171-05-0 10MG ₹22353.63 2022-06-14 Buy
Product number Packaging Price Buy
B6938 5MG ₹12329.68 Buy
PHR3434 50MG ₹19863.88 Buy
B6938 25MG ₹48106.3 Buy
90594 10MG ₹22353.63 Buy

BIS(4-HYDROXYCINNAMOYL)METHANE Chemical Properties,Uses,Production

Uses

Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activit y. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Bisdemethoxycurcumin (BDMC) is a derivative or curcumin, and represents one of the major active components of curcumin products isolated from Curcumae sp. BDMC shares similar anti-inflammatory properties with demethoxycurcumin. It inhibits LPS-induced nitric oxide (NO) production and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. BDMC also displays unique properties in that it enhances Abeta clearance by upregulating expression MGAT3 and TLR genes. BDMC potently inhibits AKR1B10.

BIS(4-HYDROXYCINNAMOYL)METHANE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 190)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Natural Remedies Pvt Ltd +91 (80) 4020-9999 New Delhi, India 110 50 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
BINBO BIOLOGICAL CO.,LTD +8618629063126 China 346 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
(1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione PARAPARADIHYDROXYDICINNAMOYLMETHANE (E,E)-BisdeMethoxycurcuMin (E,E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione CURCUMIN 3 DEMETHOXYCURCUMIN, BIS- BIS-DESMETHOXYCURCUMIN BIS(4-HYDROXYCINNAMOYL)METHANE Didemethoxycurcumin 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)- Bis(p-hydroxycinnamoyl)methane Deleted CAS No: 22608-12-4, 85801-92-9, 91884-88-7, 104024-29-5 Bisdemethoxycurcumin, 98%, from Zingiber officinale Rosc. Bisdemethoxycurcumin(BDMC) Bisdemethoxycurcumin(b) 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)- BIS(4-HYDROXYCINNAMOYL)METHANE USP/EP/BP Misdemeanour BISDEMETHOXY CURCUMIN (1E,6E)-Bis(demethoxy)curcumin (E,E)-Curcumin III,Bisdemethoxycurcumin,inhibit,(E,E)-Didemethoxycurcumin,Inhibitor,Apoptosis,Autophagy,(E,E)-Bisdemethoxycurcumin Bisdemethoxycurcumin/1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)- 33171-05-0 34939-16-0 Miscellaneous Natural Products