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DEMETHOXYCURCUMIN

CAS No.: 22608-11-3

Chemical Name:: DEMETHOXYCURCUMIN

Synonyms: emethoxycurcumin;Demethoxycurcumin;Curcumin Desmethoxy;DEMETHOXYCURCUMIN(SH);MonodeMethoxycurcuMin;Z/E-Desmethoxycurcumin;Demethoxycurcumin (AS);(2E)-DeMethoxy CurcuMin;(E,E)-demethoxycurcumin;(1E,6E)-Demethoxycurcumin

CBNumber:: CB0960423

Molecular Formula:: C20H18O5

Molecular Weight:: 338.35

MOL File:: 22608-11-3.mol

MSDS File:: SDS

Modify Date:: 2023/5/25 18:00:58

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DEMETHOXYCURCUMIN Properties

Melting point	166～170℃
Boiling point	571.4±50.0 °C(Predicted)
Density	1.282±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: ≥10mg/mL
pka	8.31±0.46(Predicted)
form	powder
color	orange
LogP	3.113 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H400
Precautionary statements	P273
Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	UN 3077 9 / PGIII
WGK Germany	2
HS Code	29145090

DEMETHOXYCURCUMIN price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	D7696	Demethoxycurcumin ≥98% (HPLC)	22608-11-3	5MG	₹17666.4	2022-06-14	Buy
Sigma-Aldrich(India)	D7696	Demethoxycurcumin ≥98% (HPLC)	22608-11-3	25MG	₹68901.13	2022-06-14	Buy
Sigma-Aldrich(India)	90593	Demethoxycurcumin analytical standard	22608-11-3	10MG	₹26488.78	2022-06-14	Buy

Product number	Packaging	Price	Buy
D7696	5MG	₹17666.4	Buy
D7696	25MG	₹68901.13	Buy
90593	10MG	₹26488.78	Buy

DEMETHOXYCURCUMIN Chemical Properties,Uses,Production

Uses

Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin. More stable than curcumin in physiological media, DMC suppresses proliferation in cancer cells at 50-100 μM. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits lipopolysaccharide induction of iNOS.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Demethoxycurcumin (DMC) is a derivative or curcumin, and represents one of the major active components of curcumin products isolated from Curcumae sp. DMC inhibits LPS-induced nitric oxide (NO) production, and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. DMC also inhibits NF-kB dependent iNOS, TNFα and IL-1β expression in LPS-treated rat microglial cells. DMC suppresses expression of MMPs and ICAM-1 in MDA-MB-231 human breast cancer cells by inhibition of NF-kB.

DEMETHOXYCURCUMIN Preparation Products And Raw materials

Raw materials

Preparation Products

DEMETHOXYCURCUMIN Suppliers

Global( 177)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Natural Remedies Pvt Ltd	+91 (80) 4020-9999	New Delhi, India	110	50	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Natural Remedy Private Limited	09019202423	Karnataka, India	17	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29901	58	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	China	3424	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	China	12210	58	Inquiry

Supplier	Advantage
Natural Remedies Pvt Ltd	50
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
Natural Remedy Private Limited	58
Pharma Affiliates	58
CLEARSYNTH LABS LTD.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Chongqing Chemdad Co., Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

22608-11-3(DEMETHOXYCURCUMIN)Related Search:

Tetrahydrocurcumin 5"-MethoxyhexahydrocurcuMin BIS(4-HYDROXYCINNAMOYL)METHANE (3S,5S)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTANE-3,5-DIOL DihydrocurcuMin

ASC-J9 HEXAHYDROCURCUMIN FLLL31 lithospermic acid 13,14-Didehydromatridin-15-one

Curcumin BIS(4-HYDROXYCINNAMOYL)METHANE DEMETHOXYCURCUMIN CURCUMIN, [3H]- CURCUMIN DIACETATE

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Feruloyl-P-hydroxycinnnamoylmethane MonodeMethoxycurcuMin (1E,6E)-1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-Methoxyphenyl)-1,6-heptadiene-3,5-d (E,E)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione 1-(4-Hydroxy-3-Methoxyphenyl)-7-(p-hydroxyphenyl)-1,6-heptadiene-3,5-dione DeMethoxyCurcuMin(DesMethoxycurcuMin) p-HydroxycinnaMoylferuloylMethane Demethoxycurcumin 1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)- DEMETHOXYCURCUMIN(SH) (2E)-DeMethoxy CurcuMin Demethoxycurcumin, 98%, from Curcuma longa L. (1E,6E)-Demethoxycurcumin Z/E-Desmethoxycurcumin 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)- Curcumin Desmethoxy DEMETHOXYCURCUMIN USP/EP/BP (E,E)-demethoxycurcumin Demethoxycurcumin (Mixture of Isomers) emethoxycurcumin Demethoxycurcumin (AS) Curcumin II|||Desmethoxycurcumin|||Monodemethoxycurcumin 22608-11-3 33173-16-3 Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals