5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS No.
- 1434-54-4
- Chemical Name:
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Synonyms
- pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
- CBNumber:
- CB4150567
- Molecular Formula:
- C22H31NO2
- Molecular Weight:
- 341.49
- MOL File:
- 1434-54-4.mol
- Modify Date:
- 2024/7/2 8:55:08
| Melting point | 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2)) |
|---|---|
| Boiling point | 508.5±50.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point | 93 °C |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| form | White to off-white solid. |
| pka | 14.95±0.70(Predicted) |
| color | White to off-white |
| EPA Substance Registry System | Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4) |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 50MG | ₹8811.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 100MG | ₹15068.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 250MG | ₹27495.5 | 2022-06-14 | Buy |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemical Properties,Uses,Production
Uses
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48465 | 58 | Inquiry |
| RD International Technology Co., Limited | 18024082417 | China | 9268 | 58 | Inquiry |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 15900491054 | China | 9267 | 58 | Inquiry |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | China | 16168 | 55 | Inquiry |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | China | 8141 | 58 | Inquiry |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | China | 24998 | 58 | Inquiry |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | China | 31130 | 58 | Inquiry |
1434-54-4(5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE)Related Search:
chevron_left
1of4
chevron_right
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-pregnen-3B-ol-20-one-16A-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
pregnenolone-16α-carbonitrile
16α-Cyano-3β-hydroxypregn-5-en-20-one
U-14975
16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
16-alpha-cyanopregnenolone
3beta-hydroxy-20-oxo-pregn-5-ene-16-alpha-carbonitril
3-hydroxy-20-oxo-,(3-beta,16-alpha)-pregn-5-ene-16-carbonitril
pcn
sc4674
PREGNENOLONE-16ALPHA-CARBONITRILE
Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
CYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 16α-carbonitrile,Inhibitor,PXR,cytochrome,inhibit
5-PREGNEN-16α-CYANO-3β-OL-20-ONE
Pregnenolone 16α-carbonitrile
1434-54-4
C22H31NO2
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Cytokines, Growth Factors and Hormones
Corticosterone
Hormones
Steroid Hormones