5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS No.
- 1434-54-4
- Chemical Name:
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Synonyms
- pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
- CBNumber:
- CB4150567
- Molecular Formula:
- C22H31NO2
- Molecular Weight:
- 341.49
- MOL File:
- 1434-54-4.mol
- Modify Date:
- 2025/4/17 18:22:24
| Melting point | 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2)) |
|---|---|
| Boiling point | 508.5±50.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point | 93 °C |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| pka | 14.95±0.70(Predicted) |
| form | White to off-white solid. |
| color | White to off-white |
| biological source | synthetic (organic) |
| EPA Substance Registry System | Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4) |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 50MG | ₹8811.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 100MG | ₹15068.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 250MG | ₹27495.5 | 2022-06-14 | Buy |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemical Properties,Uses,Production
Uses
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Suppliers
Global( 47)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Aladdin Scientific | United States | 57505 | 58 | Inquiry | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +8617705817739 | China | 53881 | 58 | Inquiry |
| Shijiazhuang suchen Chemical Technology Co. LTD | 186-33933494 18032288352 | China | 196 | 60 | Inquiry |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | China | 29784 | 58 | Inquiry |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | China | 233051 | 58 | Inquiry |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 15900491054 | China | 9522 | 58 | Inquiry |
| Shanghai Weiyite Biotechnology Co., Ltd | 15317051735 | China | 9736 | 58 | Inquiry |
1434-54-4(5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE)Related Search:
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5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-pregnen-3B-ol-20-one-16A-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
pregnenolone-16α-carbonitrile
16α-Cyano-3β-hydroxypregn-5-en-20-one
U-14975
16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
16-alpha-cyanopregnenolone
3beta-hydroxy-20-oxo-pregn-5-ene-16-alpha-carbonitril
3-hydroxy-20-oxo-,(3-beta,16-alpha)-pregn-5-ene-16-carbonitril
pcn
sc4674
PREGNENOLONE-16ALPHA-CARBONITRILE
Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
CYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 16α-carbonitrile,Inhibitor,PXR,cytochrome,inhibit
5-PREGNEN-16α-CYANO-3β-OL-20-ONE
Pregnenolone 16α-carbonitrile
Pregnenolone-16alpha-carbonitrile, Cytochrome P-450 inducer
Pregnenolone Carbonitrile, 10 mM in DMSO
1434-54-4
C22H31NO2
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Cytokines, Growth Factors and Hormones
Corticosterone
Hormones
Steroid Hormones