5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
|
- ₹8811.55 - ₹27495.5
- Product name: 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS: 1434-54-4
- MF: C22H31NO2
- MW: 341.49
- EINECS:
- MDL Number:MFCD00079212
- Synonyms:5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE;5-pregnen-3B-ol-20-one-16A-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;pregnenolone-16α-carbonitrile;16α-Cyano-3β-hydroxypregn-5-en-20-one;U-14975;16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 50MG
- 100MG
- 250MG
- ManufacturerSigma-Aldrich(India)
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging250MG
- Price₹27495.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging100MG
- Price₹15068.4
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging50MG
- Price₹8811.55
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 250MG | ₹27495.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 100MG | ₹15068.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 50MG | ₹8811.55 | 2022-06-14 | Buy |
Properties
Melting point :225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
Boiling point :508.5±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
Flash point :93 °C
storage temp. :2-8°C
solubility :Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka :14.95±0.70(Predicted)
form :White to off-white solid.
color :White to off-white
biological source :synthetic (organic)
EPA Substance Registry System :Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Boiling point :508.5±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
Flash point :93 °C
storage temp. :2-8°C
solubility :Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka :14.95±0.70(Predicted)
form :White to off-white solid.
color :White to off-white
biological source :synthetic (organic)
EPA Substance Registry System :Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at μM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7α-hydroxylase, regulating both xenobiotic and bile acid homeostasis by enhancing hepatic uptake and biliary excretion. Activation of PXR by 50 mg/kg PCN administered to obesity-prone AKR/J mice has been reported to attenuate the development of high-fat diet-induced obesity and insulin resistance.Related product price
- ORANILE
₹2200-23800 - N-OCTYL CYANIDE
₹6873.88 - Dodecanenitrile
₹3052.65-10200
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
Aladdin Scientific
DAYANG CHEM (HANGZHOU) CO.,LTD
Shanghai Maclean Biochemical Technology Co., LTD
Biosynth Biological Technology (Suzhou) Co Ltd
Cayman Chemical Company
Santa Cruz Biotechnology Inc
Shijiazhuang suchen Chemical Technology Co. LTD
