Chinese english Japanese Germany Korea

SPIROXATRINE

SPIROXATRINE Structure
CAS No.
1054-88-2
Chemical Name:
SPIROXATRINE
Synonyms
R 5188;SPIROXATRINE;Spiroxatrine (R 5188);SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5;8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-;8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE;R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one
CBNumber:
CB4157162
Molecular Formula:
C22H25N3O3
Molecular Weight:
379.45
MOL File:
1054-88-2.mol
Modify Date:
2024/7/7 20:48:41
Request For Quotation

SPIROXATRINE Properties

Melting point 215.8-218.0 °C
Boiling point 602.8±55.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility 0.1 M HCl: moderately soluble
pka 15.03±0.20(Predicted)
form powder
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

SPIROXATRINE Chemical Properties,Uses,Production

Uses

Spiroxatrine (R 5188) is a SR-1A antagonist.

Biological Activity

5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.

SPIROXATRINE Preparation Products And Raw materials

Raw materials

Preparation Products

SPIROXATRINE Suppliers

Global( 42)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81148696 +8615536356810 China 1154 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Shanghai Tachizaki Biomedical Research Center 18014399201 China 2497 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Shanghai Tachizaki Biomedical Research Center 58
TargetMol Chemicals Inc. 58
BOC Sciences 65
Service Chemical Inc. 71

1054-88-2(SPIROXATRINE)Related Search:

2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE Piperoxan 4-(DIETHYLAMINO)BUTYLAMINE 2-Isopropoxyphenol 3-PIPERIDINO-1,2-PROPANEDIOL
N-(1-METHYLPIPERIDIN-4-YL)ANILINE SPIROXATRINE Hexahydroisonicotinamide (1-Methyl-4-piperidinyl)methanamine 2-(2-Methoxyphenoxy)ethylamine
1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-(2-Hydroxyethyl)-1,4-butanediamine 1-METHYLPIPERIDINE-4-CARBALDEHYDE 1,4-Benzodioxan 2-methyl-1,4-diaminobutane
1,4-BENZODIOXAN-2-METHYLAMINE, N-METHYL- CHEMBRDG-BB 4009655 1-[1-(2-METHOXYETHYL)PIPERIDIN-4-YL]METHANAMINE
chevron_left

1of4

chevron_right
SPIROXATRINE R 5188 (+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE 8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5 R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one Spiroxatrine (R 5188) 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl- 8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 1054-88-2 Serotonin receptor