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(R)-1-Boc-3-methylpiperazine

(R)-1-Boc-3-methylpiperazine Structure
CAS No.
163765-44-4
Chemical Name:
(R)-1-Boc-3-methylpiperazine
Synonyms
tert-butyl (R)-3-methylpiperazine-1-carboxylate;(R)-4-N-BOC-2-METHYLPIPERAZINE;(R)-tert-butyl 3-Methylpiperazine-1-carboxylate;(R)-4-Boc-2-Methylpi;(R)-N-BOC-2-METHYLPIPERAZINE;(R)-4-BOC-2-METHYLPIPERAZINE;(R)-1-BOC-3-METHYLPIPERAZINE;(R)-N4-BOC-2-METHYLPIPERAZINE;(3R)-1-BOC-3-METHYLPIPERAZINE;(R)-3-Methyl-1-Boc-piperazine
CBNumber:
CB4192376
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MOL File:
163765-44-4.mol
MSDS File:
SDS
Modify Date:
2023/12/18 16:59:08

(R)-1-Boc-3-methylpiperazine Properties

Melting point 40-45 °C
Boiling point 268.7±15.0 °C(Predicted)
Density 0.997±0.06 g/cm3(Predicted)
Flash point 223 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 8.52±0.40(Predicted)
form Crystalline Powder
color White
optical activity [α]/D +16±2°, c = 1 in dioxane
InChIKey FMLPQHJYUZTHQS-MRVPVSSYSA-N
CAS DataBase Reference 163765-44-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-39-37/39
WGK Germany  3
10-34
HS Code  29335990
NFPA 704
1
2 0

(R)-1-Boc-3-methylpiperazine price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 674761 (R)-1-Boc-3-methylpiperazine 97% 163765-44-4 1G ₹6191.9 2022-06-14 Buy
ALFA India ALF-H27350-06 (R)-(+)-1-Boc-3-methylpiperazine, 97% 163765-44-4 5g ₹26422 2022-05-26 Buy
ALFA India ALF-H27350-03 (R)-(+)-1-Boc-3-methylpiperazine, 97% 163765-44-4 1g ₹7881 2022-05-26 Buy
Product number Packaging Price Buy
674761 1G ₹6191.9 Buy
ALF-H27350-06 5g ₹26422 Buy
ALF-H27350-03 1g ₹7881 Buy

(R)-1-Boc-3-methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

(R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).

(R)-4-Boc-2-methylpiperazine

(R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Global( 282)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Shanghai Boc Chemical Co., Ltd. 021-34975602; +8618721111801 China 138 58 Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 6938 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7287 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
(R)-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-N-BOC-2-METHYLPIPERAZINE (R)-N4-BOC-2-METHYLPIPERAZINE TERT-BUTYL (R)-3-METHYL-1-PIPERAZINECARBOXYLATE (R)-4-BOC-2-METHYLPIPERAZINE (R)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-1-BOC-3-METHYLPIPERAZINE (R)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE (R)-1-N-BOC-3-METHYLPIPERAZINE (R)-3-Methyl-1-Boc-piperazine (3R)-1-BOC-3-METHYLPIPERAZINE 4-BOC-2-(R)-METHYL-PIPERAZINE 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3R)- (S)-1-BOC-3-METHYL-PIPERAZINE,(R)-1-Boc-3-methylpiperazine (R)-4-N-Boc-2-methylpiperazine (R )-4-N-Boc-2-methyl piperazine (R)-2-Methylpiperazine, N4-BOC protected (R)-1-Boc-3-methylpiperazine, tert-Butyl (R)-3-methyl-1-piperazinecarboxylate (R)-4-Boc-2-piperazinecarboxylic acid (R)-3-Methyl-Piperazine-1-Carbo (3R)-3-Methylpiperazine, N1-BOC protected tert-Butyl (R)-3-methyl-1-piperazinecarboxylate acid tert-Butyl (3R)-3-methylpiperazine-1-carboxylate (R)-4-N-BOC-2-METHYL-PIPERAZINE-HCl (R)-4-Boc-2-Methylpi (R)-(+)-1-Boc-3-Methylpiperazine (R)-4-N-Boc-2-Methyl-piperazine/(R)-1-Boc-3-Methylpiperazine (R)-butyl 3-Methylpiperazine-1-carboxylate (R)-(+)-1-Boc-3-methylpiperazine,97% tert-Butyl (3R)-3-methylpiperazine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-methylpiperazine (R)-4-N-BOC-2-METHYLPIPERAZINE (R)-tert-butyl 3-Methylpiperazine-1-carboxylate tert-butyl (R)-3-methylpiperazine-1-carboxylate 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3R)- (9CI, ACI) 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3R)- (9CI ACI) (R)-tert-butyl-2- methylpiperazine-4-carboxylate 163765-44-4 345-75-7 C10H20N2O2 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Piperazines Piperaizine Piperazine series pharmacetical Piperazines