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CALMIDAZOLIUM CHLORIDE

CALMIDAZOLIUM CHLORIDE Structure
CAS No.
57265-65-3
Chemical Name:
CALMIDAZOLIUM CHLORIDE
Synonyms
R 24571;CALMIDAZOLIUM;COMPOUND 48/80;Calimidazoline;COMPOUND R24571;R 24571 CHLORIDE;Calmidazolium chlori;CALMIDAZOLIUM CHLORIDE;Calmidazolium chloride,99%;CALMODULIN INHIBITOR R 24571
CBNumber:
CB4231628
Molecular Formula:
C31H23Cl7N2O
Molecular Weight:
687.69
MOL File:
57265-65-3.mol
Modify Date:
2023/9/4 15:51:00
Request For Quotation

CALMIDAZOLIUM CHLORIDE Properties

Melting point 172-176 °C
storage temp. 2-8°C
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
form solid
color white
Water Solubility Soluble in dimethyl sulfoxide, ethanol. methanol, chloroform, and propylene glycol. Insoluble in water.
BRN 6470244

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331
Precautionary statements  P261-P280-P301+P310+P330-P302+P352+P312-P304+P340+P312-P403+P233
Safety Statements  22-24/25
RIDADR  UN 2811 6.1 / PGII
WGK Germany  3
RTECS  Gk2402500
F  3-8-10
HS Code  29332990
NFPA 704
0
2 0

CALMIDAZOLIUM CHLORIDE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C3930 Calmidazolium chloride solid 57265-65-3 5MG ₹19874.7 2022-06-14 Buy
Sigma-Aldrich(India) C2313 Compound 48/80 57265-65-3 100MG ₹11052.33 2022-06-14 Buy
Sigma-Aldrich(India) C3930 Calmidazolium chloride solid 57265-65-3 25MG ₹67461.4 2022-06-14 Buy
Sigma-Aldrich(India) C2313 Compound 48/80 57265-65-3 250MG ₹22548.48 2022-06-14 Buy
Sigma-Aldrich(India) C2313 Compound 48/80 57265-65-3 1G ₹66292.3 2022-06-14 Buy
Product number Packaging Price Buy
C3930 5MG ₹19874.7 Buy
C2313 100MG ₹11052.33 Buy
C3930 25MG ₹67461.4 Buy
C2313 250MG ₹22548.48 Buy
C2313 1G ₹66292.3 Buy

CALMIDAZOLIUM CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

Calmidazolium chloride is a small molecule CaM antagonist and calcium channel protein inhibitor. Calmidazolium chloride demonstrates noncompetitive inhibition of platelet and sarcoplasmic reticulum Ca2+-ATPase activity and shows inhibition of Ca2+?transport activity in platelet microsomes. In HeLa cells, calmidazolium chloride stimulates a mechanism of cellular Ca2+?influx distinct from store-operated Ca2+?entry and unaccompanied by Ca2+?store depletion, mobilizing stores and evoking a Ca2+?signal through activation of phospholipase C. Calmidazolium chloride is described to inhibit constitutive nitric oxide synthase (NOS) activity without affecting inducible NOS in rat aorta. The dependence upon calmodulin of neuronal NOS (nNOS) in neuroblastoma N1E-115 cells was probed with calmidazolium chloride, where it was demonstrated to increase cGMP levels indirectly indicating an increase in NO output by nNOS. Calmidazolium chloride is also described to inhibit the activity of calmodulin N-methyltransferase.

General Description

Compound 48/80, is the condensation product of N-methyl p-methoxyphenethylamine and formaldehyde.

Biological Activity

Calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca 2+ -transporting ATPase with IC 50 values of 0.15 and 0.35 μ M respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.

CALMIDAZOLIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

CALMIDAZOLIUM CHLORIDE Suppliers

Global( 49)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 China 25013 65 Inquiry
Bide Pharmatech Ltd. 400-1647117 15221909166 China 63720 58 Inquiry
Guangzhou Younan Technology Co., Ltd 020-020-82000279 18988968278 China 4324 58 Inquiry
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 China 9357 58 Inquiry
DC Chemicals 021-58447131 13564518121 China 9412 58 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29803 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
TargetMol Chemicals Inc. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Aladdin Scientific 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Bide Pharmatech Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
Zhengzhou convergence chemical co., LTD 58
DC Chemicals 58
Shanghai Maclean Biochemical Technology Co., LTD 58

CALMIDAZOLIUM CHLORIDE Spectrum

CALMIDAZOLIUM CHLORIDE(57265-65-3)1HNMR

57265-65-3(CALMIDAZOLIUM CHLORIDE)Related Search:

1-Isopropylimidazole (S)-1-(4-Chlorophenyl)ethylamine 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE 2,4-DICHLORO-ALPHA-METHYLBENZYL ALCOHOL (R)-1-(4-CHLOROPHENYL)ETHYLAMINE
Miconazole Econazole 2,2',4,4'-TETRACHLORODIBENZYL ETHER alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol 1-Ethyl-3-methylimidazolium chloride
2-AMINO-1-(4-CHLORO-PHENYL)-ETHANOL HCL CHEMBRDG-BB 9070890 1,3-DIMETHYLIMIDAZOLIUM CHLORIDE 2-HYDROXY-2-(2-CHLOROPHENYL)ETHYLAMINE HYDROCHLORIDE 1-Phenyl-2-(1-imidazolyl)ethanol
CALMIDAZOLIUM CHLORIDE 2-Amino-1-(4-chlorophenyl)ethan-1-ol 4-Chloro-alpha-methylbenzylamine
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CALMODULIN INHIBITOR R 24571 CALMIDAZOLIUM CALMIDAZOLIUM CHLORIDE COMPOUND R24571 COMPOUND 48/80 COMPOUND 48/80 TRIHYDROCHLORIDE R 24571 R 24571 CHLORIDE 1-[bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride R 24571, 1-[bis(4-Chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride, 1-[Bis(4-chlorophenyl)methyl]-3-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride 1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL)]IMIDAZOLIUM CHLORIDE 1-[BIS(P-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4 DICHLOROBENZYLOXY) PHENETHYL]-IMIDAZOLIUM CHLORIDE [1-BIS-P-CHLOROPHENYL) METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY) PHENYL]-IMIDAZOLIUM CHLORIDE 1-[BIS-(4-CHLOROPHENYL)METHYL]-3-[2-(2,4-DICHLOROPHENYL)-2-[(2,4-DICHLOROPHENYL)METHOXY]-ETHYL]-1H-IMIDAZOLIUM CHLORIDE 1-[BIS(4-CHLOROPHENYL)METHYL]-3-[2,4-DICHLORO-BETA-(2,4-DICHLOROBENZYLOXY)PHENETHYL]IMIDAZOLIUM CHLORIDE Calimidazoline Calmidazolium chloride,99% Calmidazolium Chloride - CAS 57265-65-3 - Calbiochem Calmidazolium chloride (R 24571) Calmidazolium chloride (Synonyms: R 24571) 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichloroph enyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-im idazol-3-ium chloride Calmidazolium chlori 1-(Bis(4-chlorophenyl)methyl)-3-(2-((2,4-dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazol-3-ium chloride CaMK,Calmidazolium,Inhibitor,R24571,Calmidazolium chloride,inhibit,R-24571,Calmodulin-dependent protein kinases,Calmodulin-dependent kinases,Autophagy 57265-65-3 C31H23Cl7N2O Antibiotics A to Z Antibiotics A-F Antibiotics Biochemicals and Reagents BioChemical Cell Signaling and Neuroscience Cell Biology Calcium Antagonists Enzyme Inhibitors Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Other Intracellular Calcium Signaling