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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >5-HT Receptor agonists >Prucalopride Succinate

Prucalopride Succinate

Prucalopride Succinate Structure
CAS No.
179474-85-2
Chemical Name:
Prucalopride Succinate
Synonyms
R-108512;RESOLOR; R-108512;Resolor Succinate;PRUCALOPRIDE SUCCITE;Prucalopride Impurity;Prucalopride Succinat;Priucapride succinate;Prucalopride Succinate;Prucalopride Succinate WS;PRUCALOPRIDE INTERMEDIATES
CBNumber:
CB42510031
Molecular Formula:
C22H32ClN3O7
Molecular Weight:
485.96
MOL File:
179474-85-2.mol
Modify Date:
2024/3/20 8:57:53
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Prucalopride Succinate Properties

Melting point >196°C (dec.)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Pale Brown
InChIKey QZRSNVSQLGRAID-UHFFFAOYSA-N
SMILES C(O)(=O)CCC(O)=O.O1C2=C(C(NC3CCN(CCCOC)CC3)=O)C=C(Cl)C(N)=C2CC1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H412-H302
Precautionary statements  P273-P501-P264-P270-P301+P312-P330-P501

Prucalopride Succinate Chemical Properties,Uses,Production

Chemical Properties

Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide is Off-White to Pale Brown Solid

Uses

Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.

Clinical Use

Prucalopride succinate, a first-in-class dihydrobenzofurancarboxamide, is a selective serotonin (5- HT4) receptor agonist. The drug, marketed under the brand name Resolor®, possesses enterokinetic activity and was developed by the Belgian-based pharmaceutical firm Movetis. Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation, triggering the central propulsive force for defecation.

Prucalopride Succinate Preparation Products And Raw materials

Raw materials

Preparation Products

Prucalopride Succinate Suppliers

Global( 243)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
KARPSCHEM LABORATORIES +91-7249203006 +91-7249203006 Maharashtra, India 786 58 Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
Metrochem API Private Limited +91-4069069999 +91-4069069999 Telangana, India 78 58 Inquiry
Centaur Pharmaceuticals Pvt Ltd +912266499100 Mumbai, India 33 58 Inquiry
Nuray Chemicals Pvt Ltd +91-4066616700 +91-8220444745 Tamil Nadu, India 49 58 Inquiry
Shilpa Medicare Limited (SML) +91-8532238704 +91-9320649838 Karnataka, India 61 58 Inquiry
Aruvi Labs +91-8056181939 +91-8056181939 Tamil Nadu, India 149 58 Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Viyash Life Sciences Pvt Ltd +91-4023635052 +91-4023635052 Telangana, India 213 58 Inquiry
Biophore India Pharmaceuticals Pvt Ltd +91-9100031592 +91-9030907714 Telangana, India 134 58 Inquiry
Supplier Advantage
KARPSCHEM LABORATORIES 58
Varanous Labs Pvt Ltd 58
Metrochem API Private Limited 58
Centaur Pharmaceuticals Pvt Ltd 58
Nuray Chemicals Pvt Ltd 58
Shilpa Medicare Limited (SML) 58
Aruvi Labs 58
CHEMAZON LABORATORIES 58
Viyash Life Sciences Pvt Ltd 58
Biophore India Pharmaceuticals Pvt Ltd 58

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Prucalopride Succinate Spectrum

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Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Prucalopride Succinate Prucalopride Succinate API PRUCALOPRIDE INTERMEDIATES Prucalopride Succinat Prucalopride Succinate WS Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1) Prucalopride Impurity R-108512 RESOLOR; R-108512 7-cyclopenta[b]pyrancarboxamide 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide,butanedioic acid 4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide succinate 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Butanedioic Acid Prucalopride succinate, 98.5%, a selective high affinity 5-HT4 receptor agonist Resolor Succinate Prucalopride Succinate USP/EP/BP Prucalopride Succinate (R-108512, R-93877) Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methox... Prucalopride Succinate 13CD3Q: What is Prucalopride Succinate 13CD3 Q: What is the CAS Number of Prucalopride Succinate 13CD3 TIANFU-CHEM - Prucalopride Succinate 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide,butanedioicaci PRUCALOPRIDE SUCCITE Prucalopride Succinate 4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3 -dihydrobenzofuran-7-carboxamide succinate Priucapride succinate 179474-85-2 C18H26ClN3O3C4H6O4 C22H32N3O7Cl Inhibitors