Chinese english Japanese Germany Korea

HYDROXYFLUTAMIDE

HYDROXYFLUTAMIDE Structure
CAS No.
52806-53-8
Chemical Name:
HYDROXYFLUTAMIDE
Synonyms
CS-1970;utamide;Sch-16423;Hydroxy FL;Hydroxyflutamid;HYDROXYFLUTAMIDE;hydroxyniphtholide;5-HYDROXYFLUTAMIDE;2-HYDROXY-FLUTAMIDE;Flutamide Impurity 7
CBNumber:
CB4307190
Molecular Formula:
C11H11F3N2O4
Molecular Weight:
292.21
MOL File:
52806-53-8.mol
MSDS File:
SDS
Modify Date:
2024/5/13 18:00:15
Request For Quotation

HYDROXYFLUTAMIDE Properties

Melting point 125-130°C
Boiling point 443.8±45.0 °C(Predicted)
Density 1.472
storage temp. room temp
solubility DMSO: >10mg/mL
form powder
pka 12.87±0.70(Predicted)
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  TX1466250
HS Code  2924297099
NFPA 704
0
2 0

HYDROXYFLUTAMIDE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H4166 Hydroxyflutamide ≥98% (HPLC) 52806-53-8 5MG ₹14516.33 2022-06-14 Buy
Sigma-Aldrich(India) H4166 Hydroxyflutamide ≥98% (HPLC) 52806-53-8 25MG ₹56430.73 2022-06-14 Buy
TCI Chemicals (India) H1600 Hydroxyflutamide 52806-53-8 25MG ₹9800 2022-05-26 Buy
TCI Chemicals (India) H1600 Hydroxyflutamide 52806-53-8 100MG ₹19600 2022-05-26 Buy
Product number Packaging Price Buy
H4166 5MG ₹14516.33 Buy
H4166 25MG ₹56430.73 Buy
H1600 25MG ₹9800 Buy
H1600 100MG ₹19600 Buy

HYDROXYFLUTAMIDE Chemical Properties,Uses,Production

Description

2-hydroxy Flutamide is the major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. Through competitive inhibition of the binding of testosterone to the nuclear androgen receptor (AR; IC50 = ~300-900), 2-hydroxy flutamide blocks the expression of AR target genes and prevents androgen-dependent stabilization of the AR. Compared to flutamide, 2-hydroxy flutamide is a more potent antiandrogen in vivo, demonstrating a higher binding affinity for the AR (0.1% binding affinity relative to dihydrotestosterone) and, thus, is the predominant contributor to the therapeutic effects of flutamide in the treatment of prostate cancer.

Chemical Properties

HYDROXYFLUTAMIDE is Yellow-Brown Powder

Uses

HYDROXYFLUTAMIDE is used non-steroidal antagonist Flutamide. Shown to be an antianhydrogen.

HYDROXYFLUTAMIDE Preparation Products And Raw materials

Raw materials

Propanamide, 2-methyl-2-[4-nitro-3-(trifluoromethyl)phenoxy]- 2-Methyl-2-(4-nitro-3-(trifluoroMethyl)phenoxy)propanoic Acid 4-NITRO-3-(TRIFLUOROMETHYL)PHENOL 4-Nitro-3-trifluoromethyl aniline Methyl 2-hydroxyisobutyrate

Preparation Products

HYDROXYFLUTAMIDE Suppliers

Global( 124)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Omcham Labs 08048372728Ext 857 Gujarat, India 90 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd +8618740459177 China 1142 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
Supplier Advantage
TCI Chemicals (India) Pvt. Ltd. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Omcham Labs 58
CLEARSYNTH LABS LTD. 58
Clearsynth Labs 58
Pharma Affiliates 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 58
Capot Chemical Co.,Ltd. 60
career henan chemical co 58
Hefei TNJ Chemical Industry Co.,Ltd. 58

52806-53-8(HYDROXYFLUTAMIDE)Related Search:

Flutamide Sildenafil 2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE (2-HYDROXYFLUTAMIDE) HYDROXYFLUTAMIDE, [3H]- 2-(Trifluoromethyl)benzene-1,4-diamine
4-Nitro-3-trifluoromethyl aniline 2-Amino-5-acetamidobenzotrifluoride 2-METHYL-D3-N-(4-NITRO-3-TRIFLUOROMETHYLPHENYL)-2-TRIMETHYLSILYLOXY-PROPAMIDE-3,3,3-D3 HYDROXYFLUTAMIDE Hydroxy FlutaMide-d6
4-ACETAMIDO-2-METHYLNITROBENZENE 4'-NITRO-3'-(TRIFLUOROMETHYL)ACETANILIDE N-(4-AMINO-3-METHYLPHENYL)PROPANAMIDE
chevron_left

1of3

chevron_right
2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)-propanamid hydroxyniphtholide 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide Hydroxy-Flutamide(Flutamide metabolite) 5-Hydroxyflutamide, 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide, 5-HYDROXYFLUTAMIDE HYDROXYFLUTAMIDE (2-HYDROXY-2-METHYL-N-{4''-NITRO-3''-(TRIFLUOROMETHYL)PHENYL}PROPANAMIDE) α,α,α-Trifluoro-2-Methyl-4'-nitro-M- lactotoluidide HydroxyflutaMide (Hydroxyniphtholide) a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide Hydroxyflutamide, >=98% 2-Hydroxy-2-methyl-N-(3-trifluoromethyl-4-nitrophenyl)propanamide Hydroxyflutamid N-[3-(Trifluoromethyl)-4-nitrophenyl]-2-hydroxyisobutyramide Sch-16423 alpha,alpha,alpha-Trifluoro-2-methyl-4'-nitro-m-lactotoluidide Propanamide, 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)- HYDROXYFLUTAMIDE 2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-PROPANAMIDE 2-HYDROXY-FLUTAMIDE CS-1970 2-Hydroxy-2-methyl-N-[4-nitro-3-(tr Hydroxy FL utamide Flutamide Hydroxy Impurity 2-Hydroxy-4'-nitro-3'-(trifluoromethyl)isobutyranilide Flutamide Impurity 7 2-Hydroxyflutamide (Hydroxyniphtholide) 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop Inhibitor,inhibit,prostate cancer,HFT,Flutamide,2 hydroxy Flutamide,2hydroxy Flutamide,Androgen Receptor,Hydroxyflutamide 52806-53-8 Amines Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Various Metabolites and Impurities Inhibitors Metabolites