ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Naphazoline nitrate
Naphazoline nitrate
- CAS No.
- 5144-52-5
- Chemical Name:
- Naphazoline nitrate
- Synonyms
- rinazin;Privina;naftizin;NaphazoL;naphtyzin;naphthisen;naphthizen;ine nitrate;privinenitrate;NAPHAZOLINI NITRAS
- CBNumber:
- CB4336127
- Molecular Formula:
- C14H15N3O3
- Molecular Weight:
- 273.29
- MOL File:
- 5144-52-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:09
| Melting point | 167-170 °C |
|---|---|
| solubility | Sparingly soluble in water, soluble in ethanol (96 per cent). |
| form | Solid |
| color | White to off-white |
| Sensitive | Hygroscopic |
| BRN | 3779329 |
| InChIKey | ZAHXYMFVNNUHCP-UHFFFAOYSA-N |
| CAS DataBase Reference | 5144-52-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-36/37-60-36 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NJ4376000 | |||||||||
| F | 3-10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29332900 | |||||||||
| NFPA 704 |
|
Naphazoline nitrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
antihistamine
Indications
Naphazoline hydrochloride and naphazoline nitrate are white or almost white crystalline powders soluble 1 in 6 and 1 in 36 water, respectively. These are potent sympathomimetic vasoconstrictors with a direct alpha-adrenergic receptor stimulatory action, and may be used as topical decongestants in 0.05% or 0.1% eyedrops. Frequent application of these solutions will produce a reactive hyperaemia. Instillation should not be repeated in less than 4-6 hours to avoid this rebound congestion.
Naphazoline eyedrops cause slight mydriasis and are contra-indicated in patients with actual or suspected closed-angle glaucoma.
Although not administered systemically, topical application of naphazoline has resulted in systemic absorption, and it is readily absorbed from the gastro-intestinal tract (Martindale, 1977).
Naphazoline nitrate Preparation Products And Raw materials
Global( 224)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Precise Biopharma Pvt Ltd | +91-2267828600 +91-2267828600 | Maharashtra, India | 46 | 58 | Inquiry |
| Merck Ltd | +91-2262109800 +91-2262109000 | Maharashtra, India | 272 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Rank Organics Chemical Pvt Ltd | +91-9821125942 +91-9821125942 | Maharashtra, India | 8 | 58 | Inquiry |
| Micron Pharmaceuticals | 91-22-24969511 | Maharashtra, India | 43 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Precise Biopharma Pvt Ltd | 58 |
| Merck Ltd | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Ralington Pharma | 58 |
| Rank Organics Chemical Pvt Ltd | 58 |
| Micron Pharmaceuticals | 58 |
| CHEMSWORTH | 30 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
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