Miconazole nitrate
- CAS No.
- 22832-87-7
- Chemical Name:
- Miconazole nitrate
- Synonyms
- monistat;Isoconazole IMpurity C Nitrate (Miconazole Nitrate);Ecobi;Vodol;Daktar;Florid;Aflorix;Brentan;Hi-Pick;Micatin
- CBNumber:
- CB0705402
- Molecular Formula:
- C18H14Cl4N2O.HNO3
- Molecular Weight:
- 479.14
- MOL File:
- 22832-87-7.mol
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 170-185 C |
|---|---|
| Density | 1.5000 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | 2-8°C |
| solubility | pyridine: soluble50mg/mL |
| form | Solid |
| color | white to off-white |
| optical activity | [α]25/D 0°, c = 10 in water |
| Water Solubility | Slightly soluble in water. Soluble in propylene glycol or pyridine. |
| Merck | 14,6178 |
| InChIKey | MCCACAIVAXEFAL-UHFFFAOYSA-N |
| CAS DataBase Reference | 22832-87-7(CAS DataBase Reference) |
Miconazole nitrate price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M3512 | (±)-Miconazole nitrate salt imidazole antibiotic | 22832-87-7 | 1G | ₹5791.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1163 | (±)-Miconazole nitrate salt Pharmaceutical Secondary Standard; Certified Reference Material | 22832-87-7 | 1G | ₹8356.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M3512 | (±)-Miconazole nitrate salt imidazole antibiotic | 22832-87-7 | 5G | ₹15869.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M3512 | (±)-Miconazole nitrate salt imidazole antibiotic | 22832-87-7 | 25G | ₹58682.33 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M1769 | Miconazole Nitrate | 22832-87-7 | 5G | ₹7300 | 2022-05-26 | Buy |
Miconazole nitrate Chemical Properties,Uses,Production
Description
Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-
Chemical Properties
White Solid
Uses
Antifungal (topical).
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Miconazole nitrate is an imidazole derivative and a broad spectrum antifungal drug used in the management of fungal outbreak in humans and veterinary animals.
Biological Activity
Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species.
Clinical Use
1-[2-(2,4-Dichlorophenyl)-2-[2,4-dichlorophenyl]-methoxy]ethyl]-1H-imidazole mononitrate (Monistat,Micatin) is a weak base with a pKa of 6.65. The nitric acidsalt occurs as white crystals that are sparingly soluble inwater and most organic solvents.
The free base is available in an injectable form, solubilized with polyethylene glycol and castor oil, and intended for the treatment of serious systemic fungal infections, such as candidiasis, coccidioidomycosis, cryptococcosis, petriellidiosis, and paracoccidioidomycosis. It may also be used for the treatment of chronic mucocutaneous candidiasis. Although serious toxic effects from the systemic administration of miconazole are comparatively rare, thrombophlebitis, pruritus, fever, and gastrointestinal upset are relatively common. Miconazole nitrate is supplied in various dosage forms (cream, lotion, powder, and spray) for the treatment of tinea infections and cutaneous candidiasis. Vaginal creams and suppositories are also available for the treatment of vaginal candidiasis. A concentration of 2% of the salt is used in most topical preparations.
Miconazole nitrate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Halcyon Labs Pvt. Ltd | +919833750169 | Mumbai, India | 17 | 58 | Inquiry |
| Unilab Company | +91-912228260263 +91-63917864522 | Tamil Nadu, India | 43 | 58 | Inquiry |
| FDC Limited | +912226782653 | Mumbai, India | 30 | 58 | Inquiry |
| Kenoor Organics Private Limited | +91-7227026011 +91-7227026012 | Gujarat, India | 29 | 58 | Inquiry |
| Om Pharmaceutical Industries | +91-2502344639 +91-9822376539 | Maharashtra, India | 32 | 58 | Inquiry |
| Sharon Bio Medicine Ltd | +91-9769026333 +91-9821911142 | Mumbai, India | 12 | 58 | Inquiry |
| Gufic Group | +91-2267261000 +91-2267261000 | Maharashtra, India | 22 | 58 | Inquiry |
| Afton Pharma | +91-9712000202 +91-9712000202 | Gujarat, India | 63 | 58 | Inquiry |
| Neugen Labs | +91-8133254502 +91-8133254502 | Karnataka, India | 195 | 58 | Inquiry |
| Humble Healthcare Limited | +91-9720093000 +91-8006400378 | Uttar Pradesh, India | 141 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Halcyon Labs Pvt. Ltd | 58 |
| Unilab Company | 58 |
| FDC Limited | 58 |
| Kenoor Organics Private Limited | 58 |
| Om Pharmaceutical Industries | 58 |
| Sharon Bio Medicine Ltd | 58 |
| Gufic Group | 58 |
| Afton Pharma | 58 |
| Neugen Labs | 58 |
| Humble Healthcare Limited | 58 |
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