Elemicin
- CAS No.
- 487-11-6
- Chemical Name:
- Elemicin
- Synonyms
- Elemicine;1,2,3-trimethoxy-5-prop-2-enylbenzene;5-ALLYL-1,2,3-TRIMETHOXYBENZENE;elemin;ELEMICIN;ELIMICIN;3,4,5-Trimethoxyallylbenzene;5-allyl-1,2,3-trimethoxy-benzen;4-allyl-1,2,6-trimethoxybenzene;1-ALLYL-3,4,5-TRIMETHOXYBENZENE
- CBNumber:
- CB4352387
- Molecular Formula:
- C12H16O3
- Molecular Weight:
- 208.25
- MOL File:
- 487-11-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:03:01
| Boiling point | 152-156 °C |
|---|---|
| Density | 1.0630 g/cm3 |
| storage temp. | Amber Vial, -20°C Freezer |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| Odor | at 100.00 %. spice flower |
| Odor Type | spicy |
| Stability | Light Sensitive |
| LogP | 2.298 (est) |
| NIST Chemistry Reference | Benzene, 1,2,3-trimethoxy-5-(2-propenyl)-(487-11-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| HS Code | 2909309090 | |||||||||
| NFPA 704 |
|
Elemicin Chemical Properties,Uses,Production
Description
Elemicin is a trioxygenated phenylpropane that has been found in A. dracunculus. It is active against S. aureus, B. subtilis, and C. albicans (MICs = 600, 2,500, and 1,000 mg/L, respectively) but not E. coli, K. pneumoniae, P. aeruginosa (MICs = >8,000 mg/L for all), or L. monocytogenes (MIC = >3,000 mg/L). Elemicin is toxic to mice following metabolic activation to 1’-hydroxyelemicin by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. It increases plasma and hepatic triglyceride levels, decreases stearoyl-CoA desaturase 1 (Scd1) expression, and induces hepatomegaly in mice when administered at a dose of 500 mg/kg per day for three weeks.
Chemical Properties
Clear Colorless Oil
Uses
A constituent of the essential oil of nutmeg and is responsible for the psychoactive effects of nutmeg. Also a minor constituent of the oleoresin and essential oil of Manila elemi (Canarium luzonicum). Exhibits anticholinergic-like effects in humans.
Synthesis
Prod. :
1) by isolation from Elemi oil (high-boiling
fractions).
2) from Dimcthylpyrogallol plus Allyl bromide,
via 2,6-Dimethyl pyrogallol allylether.
This is heated in a Claisen-rearrangement
reaction to yield 4-Hydroxy-3,5-dimethoxy
allylbenzene. The latter is methylated to
yield Elemicine.
3) From Eugenol via 5-Hydroxyeugenol.
Elemicin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3777 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
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