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RO 31-8220 METHANESULFONATE

RO 31-8220 METHANESULFONATE Structure
CAS No.
125314-64-9
Chemical Name:
RO 31-8220 METHANESULFONATE
Synonyms
RO-31-8220;RO 31-8220 MESYLATE;BisindolylMaleiMide IX;Bisindoylmaleimidine IX;RO 31-8220 METHANESULFONATE;Ro 31-8220 methanesulfonate salt;BISINDOLYLMALEIMIDE IX METHANESULFONATE;BISINDOYLMALEIMIDINE IX METHANESULFONATE;Ro 31-8220 mesylate (Bisindolylmaleimide IX);3-[1-3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL) MALEIMIDE
CBNumber:
CB4355393
Molecular Formula:
C25H23N5O2S
Molecular Weight:
457.55
MOL File:
125314-64-9.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:16
Request For Quotation

RO 31-8220 METHANESULFONATE Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: 7.3 mg/mL
pka 7.90±0.60(Predicted)
form solid
color orange to red

SAFETY

Risk and Safety Statements

WGK Germany  3

RO 31-8220 METHANESULFONATE Chemical Properties,Uses,Production

Biological Activity

Protein kinase C inhibitor, with activity at other protein kinases (IC 50 values are 33, 3, 8, 15 and 38 nM for PKC α , MAPKAP-K1b, MSK1, GSK3 β and S6K1 respectively). Activates JNK and glycogen synthase, and inhibits MAPK and ERK2, in rat adipocytes and L6 myotubes. Also inhibits voltage-dependent Na + channels in the micromolar range.

RO 31-8220 METHANESULFONATE Preparation Products And Raw materials

Raw materials

Preparation Products

RO 31-8220 METHANESULFONATE Suppliers

Global( 75)Suppliers
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Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Absin Bioscience Inc. 021-38015121 CHINA 6661 58 Inquiry
Shanghai Shanran Biotechnology Co., Ltd. 15900853496 CHINA 1563 58 Inquiry
Beijing Bolide Biotechnology Co., Ltd. 010-51653916 CHINA 6172 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Shanghai Yupu Chemical Technology Co., Ltd. 021-61842042 18964386050 CHINA 1328 58 Inquiry
Supplier Advantage
Career Henan Chemica Co 58
InvivoChem 58
LEAPCHEM CO., LTD. 58
Amadis Chemical Company Limited 58
ApexBio Technology 58
Absin Bioscience Inc. 58
Shanghai Shanran Biotechnology Co., Ltd. 58
Beijing Bolide Biotechnology Co., Ltd. 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Shanghai Yupu Chemical Technology Co., Ltd. 58

125314-64-9(RO 31-8220 METHANESULFONATE)Related Search:

Silver GF109203X RO 31-8220 (BISINDOYLMALEIMIDINE IX) RO-31-8220 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione
RO 31-8220 METHANESULFONATE
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BISINDOLYLMALEIMIDE IX METHANESULFONATE BISINDOYLMALEIMIDINE IX METHANESULFONATE RO-31-8220 RO 31-8220 MESYLATE RO 31-8220 METHANESULFONATE 3-[3-[2,5-DIHYDRO-4-(1-METHYL-1H-INDOL-3-YL)-2,5-DIOXO-1H-PYRROL-3-YL]-1H-INDOL-1-YL]PROPYL CARBAMIMIDOTHIOIC ACID ESTER MESYLATE 3-[1-3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL) MALEIMIDE 3-[1-[3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL)MALEIMIDE METHANESULFONATE 2-[1-[3-(AMIDINOTHIO)PROPYL]-1H-INDOL-3-YL]-3-(1-METHYLINDOL-3-YL)-MALEIMIDE METHANESULFONATE BisindolylMaleiMide IX 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate salt Bisindoylmaleimidine IX Ro 31-8220 methanesulfonate salt 3-[1-[3-(Amidinothio)propyl-1H-indol-3-yl]-3-(1-methyl-1H-indol-3-yl)maleimide] meslate Ro 31-8220 mesylate (Bisindolylmaleimide IX) Carbamimidothioic acid, 3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl ester 125314-64-9 C25H23N5O2SCH3SO3H Protein Kinase