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DEFEROXAMINE MESYLATE

DEFEROXAMINE MESYLATE Structure
CAS No.
138-14-7
Chemical Name:
DEFEROXAMINE MESYLATE
Synonyms
DFOM;desferal;DESFERRIOXAMINE MESYLATE;deferoxaminebmesylate;Desferioxamine mesylate;desferrioxamine mesilate;DEFEROXAMINE MESYLATE SALT;Prestwick_988;desferalmesylate;deferoxaminemesilate
CBNumber:
CB4372020
Molecular Formula:
C26H52N6O11S
Molecular Weight:
656.79
MOL File:
138-14-7.mol
MSDS File:
SDS
Modify Date:
2024/4/24 17:21:45

DEFEROXAMINE MESYLATE Properties

Melting point 148-149°
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
color white to off-white
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Safety Statements  22-24/25
WGK Germany  2
RTECS  UG5310000
HS Code  29280000
Toxicity man,TDLo,parenteral,16gm/kg/34W-I (16000mg/kg),CARDIAC: PERICARDITISGASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINEBLOOD: OTHER CHANGES,American Journal of Kidney Diseases. Vol. 10, Pg. 71, 1987.

DEFEROXAMINE MESYLATE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D9533 Deferoxamine mesylate salt powder, ≥92.5% (TLC) 138-14-7 1G ₹16367.4 2022-06-14 Buy
Product number Packaging Price Buy
D9533 1G ₹16367.4 Buy

DEFEROXAMINE MESYLATE Chemical Properties,Uses,Production

Description

Deferoxamine is a bacterial siderophore that chelates iron. It is used to experimentally inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 μM), thus preventing the degradation of isoforms of hypoxia inducible factor during normoxia. Deferoxamine has applications in diseases that are characterized by high levels of circulating iron, such as thalassemia major.

Chemical Properties

DEFEROXAMINE MESYLATE is white or almost white powder.

Uses

DEFEROXAMINE MESYLATE is an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients

DEFEROXAMINE MESYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 200)Suppliers
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SNECOFRi Pvt Ltd +91-9032850129 +91-9032850129 Telangana, India 404 58 Inquiry
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deferoxaminemesilate deferoxaminemethanesulfonate desferalmesylate desferalmethanesulfonate desferrioxaminebmesylate Deferoxamine Mesylate (300 mg) N-[5-[3-[(5-aMinopentyl)hydroxycarbaMoyl]propionaMido]pentyl]-3-[[5-(N-hydroxyacetaMido) N1-(5-aMinopentyl)-N1-hydroxy-N4-[5-[[4-[[5-(acetylhydroxyaMino)pentyl]aMino]-1,4-dioxobutyl]hydroxyaMino]pentyl]butanediaMide Methanesulfonate desferrioxaminebmethanesulfonate monomethanesulfonate(sa propionohydroxamicacid,n-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido) Butanediamide, N-5-4-5-(acetylhydroxyamino)pentylamino-1,4-dioxobutylhydroxyaminopentyl-N-(5-aminopentyl)-N-hydroxy-, monomethanesulfonate (salt) STARCHDEFEROXAMINECONJUGATE Desferrioxamine mesylate salt Prestwick_988 Deferoxamine mesylate salt,DFOM, Deferoxamine methanesulfonate salt, Desferrioxamine mesylate salt Deferoxamine Mesylate (500 mg) DEFEROXAMINE METHANESULFONATE SALT DEFEROXAMINE MESYLATE N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate Deferoxamine Mesilate RS Deferoxamine mesilate CRS Deferoxamine for system suitability DEFEROXAMINE MESYLATE USP/EP/BP Deferoxamine Mesylate (1166003) deferoxaminebmesylate desferal DFOM DESFERRIOXAMINE MESYLATE DEFEROXAMINE MESYLATE SALT Desferioxamine mesylate desferrioxamine mesilate esferrioxamineBmesylate N1-(5-(4-((5-Aminopentyl)amino)-4-oxobutanamido)pentyl)-N1-hydroxy-N4-(5-(N-hydroxyacetamido)pentyl)succinamide methanesulfonate HIFs,neovascularization,TAMSCs,diabetes mellitus,Akt,PKB,Protein kinase B,Apoptosis,Autophagy,SH-SY5Y,Hypoxia-inducible factors,Deferoxamine,Deferoxamine Mesylate,Inhibitor,MEFs,cancer,Alzheimer’s disease,HIF-PH,Reactive Oxygen Species,BMMSCs,inhibit,HIF/HIF Prolyl-Hydroxylase,COVID-19 Deferiprone Impurity 3 Deferoxamine mesylate USP/Ph. Eur 138-14-7 C26H52N6O11S C25H48N6O8CH4O3S C25H48N6O8CH4SO3 Inhibitors DESFERAL Pharmaceuticals Aliphatics Amines Chelating Agents & Ligands Intermediates & Fine Chemicals