3-(2-Pyrrolidinyl)pyridine
- CAS No.
- 5746-86-1
- Chemical Name:
- 3-(2-Pyrrolidinyl)pyridine
- Synonyms
- DL-NORNICOTINE;(R,S)-NORNICOTINE;NORNICOTINE, DL-;(+/-)-NORNICOTINE;Nicotine USP RC F;(+/-)-nornicotine;DL-Nornicotine,96%;beta-dl-nornicotine;(+ -)-NORNICOTINE 98+%;Sertindole Impurity 20
- CBNumber:
- CB4385206
- Molecular Formula:
- C9H12N2
- Molecular Weight:
- 148.21
- MOL File:
- 5746-86-1.mol
- Modify Date:
- 2024/8/7 19:09:42
| Melting point | 235-236 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 107-108°C 2mm |
| Density | 1,074 g/cm3 |
| refractive index | 1.54 |
| Flash point | 101°C |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | liquid |
| pka | 9.09±0.10(Predicted) |
| color | yellow |
| Specific Gravity | 1.074 |
| Water Solubility | Soluble in acetone, chloroform and water (50mg/ml). |
| Merck | 14,6712 |
| BRN | 81968 |
| Stability | Hygroscopic, Light Sensitive, Moisture Sensitive |
| CAS DataBase Reference | 5746-86-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi,T,F | |||||||||
| Risk Statements | 20/21/22-36/37/38-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 26-36/37-45-16-7 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QS6350000 | |||||||||
| F | 3-10 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29399990 | |||||||||
| Toxicity | LDLo ipr-rat: 6 mg/kg AJEBAK 25,83,47 | |||||||||
| NFPA 704 |
|
3-(2-Pyrrolidinyl)pyridine price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N3018 | (±)-Nornicotine ≥98% (TLC), liquid | 5746-86-1 | 25MG | ₹23111.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR3063 | Nicotine Related Compound F pharmaceutical secondary standard, certified reference material | 5746-86-1 | 50MG | ₹41308.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N3018 | (±)-Nornicotine ≥98% (TLC), liquid | 5746-86-1 | 50MG | ₹39900.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N-071 | (±)-Nornicotine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 5746-86-1 | 1ML | ₹9788.8 | 2022-06-14 | Buy |
3-(2-Pyrrolidinyl)pyridine Chemical Properties,Uses,Production
Description
(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC50 values of approximately 4 and 17 μM, respectively, when expressed in Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.
Chemical Properties
Colourless Oil
Uses
3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).
Safety Profile
Poison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE
3-(2-Pyrrolidinyl)pyridine Preparation Products And Raw materials
Global( 199)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co.,Ltd | +8613288715578 | China | 830 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9332 | 55 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |
5746-86-1(3-(2-Pyrrolidinyl)pyridine)Related Search:
N-Vinyl-2-pyrrolidone
3-(Pyrrolidin-2-yl)pyridine hydrochloride
3-(pyrrolidin-2-yl)pyridine dihydrochloride
Nicotine
(+/-)-COTININE-D3
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1of4
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NORNICOTINE, DL-
(+/-)-NORNICOTINE
(+-)-1’-demethylnicotine
beta-dl-nornicotine
3-PYRROLIDIN-2-YLPYRIDINE
2-[3-PYRIDYL]PYRROLIDINE
2-[3-PYRIDYL]PYRROLIDONE
(+/-)-3-(2-PYRROLIDINYL)PYRIDINE
3-(2-PYRROLIDINYL)PYRIDINE
DL-2-(3-Pyridyl)pyrrolidine
(+ -)-NORNICOTINE 98+%
DL-Nornicotine,96%
2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine
Nicotine, 1'-demethyl-, (+-)-
Pyridine, 3-(2-pyrrolidinyl)-, (+-)- (9ci)
(±)-Nornicotine,2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine
DL-Nornicotine/3-(Pyrrolidin-2-yl)pyridine
2-(3-Pyridinyl)pyrrolidine
2-(Pyridin-3-yl)pyrrolidine
(RS)-Nornicotine (1.0 Mg/ML in Methanol)
3-(2-Pyrrolidyl)pyridine
(±)-Nornicotine solution
Pyridine, 3-(2-pyrrolidinyl)-
Nicotine Related Compound F
Nicotine USP RC F
Nicotine USP Related Compound F (rac-Nicotine EP Impurity F)
Nicotine Related Compound F (20 mg)
(2S)-2-(3-Pyridinyl)pyrrolidinium
(+/-)-nornicotine
(R,S)-NORNICOTINE
DL-NORNICOTINE
(+/-)-Nornicotine, 3-(2-Pyrrolininyl)pyridine
3-[(2S)-pyrrolidin-2-yl]pyridine (nornicotine)
Nicotine EP Impurity F as Racemate
Sertindole Impurity 20
rac-Nicotine EP Impurity F
5746-86-1
AMINE
BioChemical
Cell Biology
Cell Signaling and Neuroscience
Ion Channels
Ligand-Gated Ion Channels
Nicotinic Acetylcholine Receptor Modulators
Metabolites & Impurities
Aromatics
Chiral Reagents
Heterocycles
Mutagenesis Research Chemicals
pharmacetical
Nicotine Derivatives
Benzenes
Heterocycle-Pyridine series
Alkaloids