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VASICINONE

VASICINONE Structure
CAS No.
486-64-6
Chemical Name:
VASICINONE
Synonyms
VASICINONE;l-Vasicinone;2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one;(3R)-2,3-Dihydro-3β-hydroxypyrrolo[2,1-b]quinazoline-9(1H)-one;Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-3-hydroxy-, (3S)-
CBNumber:
CB4385271
Molecular Formula:
C11H10N2O2
Molecular Weight:
202.21
MOL File:
486-64-6.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:09

VASICINONE Properties

Melting point 200-202℃
Boiling point 320.7°C (rough estimate)
Density 1.50
refractive index 1.5300 (estimate)
solubility Soluble in chloroform and ethanol;
form powder
pka 12.76±0.20(Predicted)
color White
Water Solubility 1.597g/L(25 ºC)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P501-P270-P264-P301+P312+P330
NFPA 704
0
2 0

VASICINONE Chemical Properties,Uses,Production

Description

A further alkaloid present in Adhatoda vasica and Peganum harmala, this base forms colourless crystals from 95 per cent EtOH. It has [α]22D - 100° (c 0.5, CHCL3) and the ultraviolet spectrum has absorption maxima at 227, 272, 302 and 315 mfJ.. The alkaloid yields a series of crystalline salts with mineral acids, e.g. the hydrochloride, m.p. 232-4°C; hydro bromide, m.p. 254-5°C (dec.); hydriodide, m.p. 222-6°C (dec.); nitrate, m.p. 138-9° C (dec.) and the sulphate, m.p. l82-5°C (dec.). The optically inactive form of the base has been prepared synthetically, m.p. 211- 2°C. The alkaloid is an active bronchodilator.

References

Ghose et al., J. Chem. Soc., 2740 (1932)
Morris, Horford, Adams., J. Amer. Chem. Soc., 57,951 (1935)
Mehta, Naravane, Desai., J. Org. Chem., 28, 445 (1963)

VASICINONE Preparation Products And Raw materials

Raw materials

Preparation Products

VASICINONE Suppliers

Global( 85)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Natural Remedies Pvt Ltd +91 (80) 4020-9999 New Delhi, India 110 50 Inquiry
Biosyn Research Chemicals +91 9346022300/+91 9399339999 Telangana, India 1340 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 19947 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
VASICINONE (3R)-2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one (3R)-2,3-Dihydro-3β-hydroxypyrrolo[2,1-b]quinazoline-9(1H)-one 2,3-Dihydro-3-hydroxypyrrolo[2,1-b]quinazolin-9(1H)-one l-Vasicinone Pyrrolo[2,1-b]quinazolin-9(1H)-one,2,3-dihydro-3-hydroxy-, (3S)- 486-64-6 Cl1H10N2O2 Alkaloids