D-(+)-Maltose monohydrate
- CAS No.
- 6363-53-7
- Chemical Name:
- D-(+)-Maltose monohydrate
- Synonyms
- D-MALTOSE;MALTOSE MONOHYDRATE;D-MALTOSE MONOHYDRATE;Maltose H;MALTOBIOSE;D-MALATOSE;MALT SUGAR;Maltose RS;MALTOSE H2O;Maltose,92%
- CBNumber:
- CB4442570
- Molecular Formula:
- C12H24O12
- Molecular Weight:
- 360.31
- MOL File:
- 6363-53-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/3 15:34:43
| Melting point | 119-121 °C (dec.)(lit.) |
|---|---|
| alpha | 137 º (c=4, H2O, NH3) |
| storage temp. | room temp |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | White |
| PH | 5.0-7.0 (25℃, 0.5M in H2O) |
| optical activity | [α]20/D +130±2°, 24 hr, c = 4% in H2O |
| Water Solubility | 1080 g/L (20 ºc) |
| λmax |
λ: 260 nm Amax: 0.08 λ: 280 nm Amax: 0.07 |
| Merck | 14,5714 |
| BRN | 5784659 |
| CAS DataBase Reference | 6363-53-7(CAS DataBase Reference) |
| NIST Chemistry Reference | «beta»-Maltose monohydrate(6363-53-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 33-63-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OO5250000 | |||||||||
| F | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 17029010 | |||||||||
| NFPA 704 |
|
D-(+)-Maltose monohydrate price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M9171 | D-(+)-Maltose monohydrate BioXtra, ≥99% | 6363-53-7 | 10MG | ₹3830.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1497 | Maltose Monohydrate Pharmaceutical Secondary Standard; Certified Reference Material | 6363-53-7 | 1G | ₹11065.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9171 | D-(+)-Maltose monohydrate BioXtra, ≥99% | 6363-53-7 | 100G | ₹11491.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9171 | D-(+)-Maltose monohydrate BioXtra, ≥99% | 6363-53-7 | 500G | ₹24924.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M5895 | D-(+)-Maltose monohydrate powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% | 6363-53-7 | 500G | ₹18660 | 2022-06-14 | Buy |
D-(+)-Maltose monohydrate Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
D-(+)-Maltose monohydrate, is commonly found in foods and commonly utilized in brewing processes. It is also used in various culture media in the cell and tissue culture applications. D-(+)-Maltose Monohydrate is used as a substrate for α-glucosidase. It is also used as a substrate for the identification, differentiation and characterization of enzymes such as maltase(s); maltose α-D-glucosyltransferase(s); maltose-transporting ATPase(s); maltose O-acetyltransferase(s) and maltose epimerase(s) and phosphorylase(s). D-Maltose is used to study maltose-binding proteins and disaccharide transport systems.
Production Methods
Maltose monohydrate is prepared by the enzymatic degradation of starch.
General Description
Maltose monohydrate is commonly used as a tablet filler or excipient in pharmaceutical industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical Applications
Maltose is a disaccharide carbohydrate widely used in foods and
pharmaceuticals. In parenteral products, maltose may be used as a
source of sugar, particularly for diabetic patients.
Crystalline maltose is used as a direct-compression tablet
excipient in chewable and nonchewable tablets.
Safety
Maltose is used in oral and parenteral pharmaceutical formulations
and is generally regarded as an essentially nontoxic and nonirritant
material. However, there has been a single report of a liver
transplantation patient with renal failure who developed hyponatremia
following intravenous infusion of normal immunoglobulin
in 10% maltose. The effect, which recurred on each of four
successive infusions, resembled that of hyperglycemia and was
thought to be due to accumulation of maltose and other osmotically
active metabolites in the extracellular fluid.
LD50 (mouse, IV): 26.8 g/kg
LD50 (mouse, SC): 38.6 g/kg
LD50 (rabbit, IV): 25.2 g/kg
LD50 (rat, IP): 30.6 g/kg
LD50 (rat, IV): 15.3 g/kg
LD50 (rat, oral): 34.8 g/kg
storage
Maltose should be stored in a well-closed container in a cool, dry place.
Purification Methods
Purify maltose by chromatography from aqueous solution on to a charcoal/Celite (1:1) column, wash it with water to remove glucose and other monosaccharides, then elute it with aqueous 75% EtOH. Crystallise it from water, aqueous EtOH or EtOH containing 1% nitric acid. Dry it as the monohydrate at room temperature under vacuum over H2SO4 or P2O5. Also purify it by dissolving it in MeOH, evaporating to a syrup which on standing for 12hours in contact with 1/10th its volume of H2O gives crystals of the monohydrate. Its iodine number is 55.5. The osazone has m 200o(dec) and [] D 20 +58o (c 1.4, H2O). [Howarth et al. J Chem Soc 793 1937, Beilstein 17 III/IV 3057, 17 V 189.]
Incompatibilities
Maltose may react with oxidizing agents. A Maillard-type reaction may occur between maltose and compounds with a primary amine group, e.g. glycine, to form brown-colored products.
Regulatory Status
In the USA, maltose is considered as a food by the FDA and is therefore not subject to food additive and GRAS regulations. Included in the FDA Inactive Ingredients Database (oral solutions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral products available in a number of countries worldwide.
D-(+)-Maltose monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| S D Fine Chem Limited | +91-9323715856 +91-9323715856 | Maharashtra, India | 368 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| FINAR LTD | +91 - 2717 - 616717 | New Delhi, India | 660 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| UNILOSA INTERNATINAL PRIVATE LIMITED | 58 |
| JSK Chemicals | 58 |
| S D Fine Chem Limited | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| FINAR LTD | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Central Drug House(P) Ltd. | 58 |
| Triveni chemicals | 58 |