ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Thiol / thiol >4'-Methylthioacetophenone

4'-Methylthioacetophenone

CAS No.: 1778-09-2

Chemical Name:: 4'-Methylthioacetophenone

Synonyms: Ethanone, 1-[4-(methylthio)phenyl]-;4-(METHYLTHIO)ACETOPHENONE;4-(Methyl thio);p-Acetylthioanisole;4'-Methylthioacetoph;Glycerol Impurity 24;4-(ACETYL)THIOANISOLE;Etoricoxib Impurity 61;4-THIOMETHYLACETOPHENONE;4'-Methylthioacetophenone

CBNumber:: CB4454274

Molecular Formula:: C9H10OS

Molecular Weight:: 166.24

MOL File:: 1778-09-2.mol

MSDS File:: SDS

Modify Date:: 2023/4/23 13:52:06

Request For Quotation

4'-Methylthioacetophenone Properties

Melting point	80-82 °C(lit.)
Boiling point	135 °C
Density	1.1369 (rough estimate)
refractive index	1.5600 (estimate)
Flash point	135°C/1mm
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform, Methanol
form	Solid
color	White to Off-White
BRN	1860517
CAS DataBase Reference	1778-09-2(CAS DataBase Reference)
NIST Chemistry Reference	4-CH3S-C6H4-COCH3(1778-09-2)
EPA Substance Registry System	4'-(Methylmercapto)acetophenone (1778-09-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

Hazard Note

Irritant

HS Code

29309099

NFPA 704

	1
2		0

4'-Methylthioacetophenone price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	396583	4′-(Methylthio)acetophenone 97%	1778-09-2	1G	₹1948.5	2022-06-14	Buy
TCI Chemicals (India)	M1672	4'-(Methylthio)acetophenone min. 98.0 %	1778-09-2	5G	₹3800	2022-05-26	Buy
TCI Chemicals (India)	M1672	4'-(Methylthio)acetophenone min. 98.0 %	1778-09-2	25G	₹9700	2022-05-26	Buy

Product number	Packaging	Price	Buy
396583	1G	₹1948.5	Buy
M1672	5G	₹3800	Buy
M1672	25G	₹9700	Buy

4'-Methylthioacetophenone Chemical Properties,Uses,Production

Chemical Properties

White to light yellow crystal powde

Uses

4′-(Methylthio)acetophenone may be used for the synthesis of Vioxx (Rofecoxib), an non-steroidal anti-inflammatory drug (NSAID). It may be used in the synthesis of (E)-1-[4-(methylsulfanyl)phenyl]-3-phenylprop-2-en-1-one.

General Description

4′-(Methylthio)acetophenone (4-(Methylthio)acetophenone, p-(methylthio) acetophenone, 4-MTAP) is a sulphur containing organic building block. It is a key intermediate in drug synthesis. Its industrial preparation, via Friedel-Crafts acylation reaction in the presence of aluminium chloride as catalyst and acetyl chloride as acylating agent has been reported. It has been prepared by the acetylation reaction of thioanisole with acetic anhydride in the presence of solid acid catalyst.

4'-Methylthioacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-METHYLTHIOPHENYL)PYRIDINE JR-13707, 3-(4-(Methylthio)phenyl)-1H-pyrazol-5-amine, 97% Ethyl 3-[4-(Methylsulfanyl)phenyl]-3-oxopropanoate

4'-Methylthioacetophenone Suppliers

Global( 249)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
Bhavesh Chem Labs	+91 9182312179	Telangana, India	322	58	Inquiry
VGS SYNTHESIS PRIVATE LIMITED	+91-9866975588 +91-9866975588	Hyderabad, India	1818	58	Inquiry
Swadev Chemicals	+91-9898998064 +91-7203031021	Gujarat, India	19	58	Inquiry
Karvy Therapeutics Pvt Ltd	+91-9824044913 +91-9824044913	Gujarat, India	10	58	Inquiry
SANIKA CHEMICALS PVT.LTD.	+091-22-27572545/27570607	NaviMumbai, India	38	58	Inquiry
Oceanic Pharmachem Pvt., Ltd. (OPPL)	91-22-42128600	Maharashtra, India	947	58	Inquiry
Karvy Therapeutics Pvt. Ltd.	91-281-2783375	Gujarat, India	7	58	Inquiry
Swadev Chemicals	91-9898998064	Gujarat, India	19	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry

Supplier	Advantage
GLR Innovations	58
Bhavesh Chem Labs	58
VGS SYNTHESIS PRIVATE LIMITED	58
Swadev Chemicals	58
Karvy Therapeutics Pvt Ltd	58
SANIKA CHEMICALS PVT.LTD.	58
Oceanic Pharmachem Pvt., Ltd. (OPPL)	58
Karvy Therapeutics Pvt. Ltd.	58
Swadev Chemicals	58
CLEARSYNTH LABS LTD.	58

4'-Methylthioacetophenone Spectrum

4'-Methylthioacetophenone(1778-09-2)¹HNMR 4'-Methylthioacetophenone(1778-09-2)FT-IR 4'-Methylthioacetophenone(1778-09-2)IR

1778-09-2(4'-Methylthioacetophenone)Related Search:

4'-Bromoacetophenone Acetophenone 4'-Methylacetophenone 4'-Methoxyacetophenone 4-Aminoacetophenone

ISOMETHIOZIN PHENYL VALERATE PIPERACETAZINE (250 MG) 2-Chloroacetophenone 3-Methoxyacetophenone

Diphenyl ether 4-Fluoroacetophenone 4'-Hydroxyacetophenone 4-Nitroacetophenone 3'-Methylacetophenone

4-(Trifluoromethylthio)phenol 3-Nitroacetophenone 4'-Chloroacetophenone

chevron_left

1of4

chevron_right

4-(Methyl thio) Ethanone,1-[4-(methylthio) 4-(METHYLTHIO)ACETOPHENONE 99% 4-THIOMETHYLACETOPHENONE Dodecane-1-sulfonyl chloride 1-Acetyl-4-(methylthio)benzene Methyl 4-acetylphenyl sulfide Methyl(4-acetylphenyl) sulfide p-Acetylthioanisole 4'-(Methylthio)acetophenone,97% 4'-Methylthioacetoph 1-[4-(Methylsulfanyl)phenyl]ethan-1-one 1-[4-(Methylsulphanyl)phenyl]ethan-1-one, 4-Acetylthioanisole 1-[4-(METHYLSULFANYL)PHENYL]ETHANONE 1-[4-(methylthio)phenyl]ethan-1-one 1-[4-(METHYLTHIO)PHENYL]ETHANONE 4-METHYLMERCAPTOACETOPHENONE 4'-(METHYLTHIO)ACETOPHENONE P-(METHYLTHIO)ACETOPHENONE 4-(ACETYL)THIOANISOLE 4'-(Methylthio)acetophenone> Etoricoxib Impurity 61 Ethanone, 1-[4-(methylthio)phenyl]- 4-(METHYLTHIO)ACETOPHENONE 4 ′- (meththyl) phenylacetone Glycerol Impurity 24 4'-Methylthioacetophenone 1778-09-2 C9H10OS CH3SC6H4COCH3 Organic Building Blocks Sulfur Compounds Sulfides/Disulfides Building Blocks Osteoarthritis and Rheumatoid Arthritis Organic Building Blocks Sulfides/Disulfides Sulfur Compounds Aromatic Acetophenones & Derivatives (substituted)