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POMALIDOMIDE-PEG2-CO2H

POMALIDOMIDE-PEG2-CO2H Structure
CAS No.
2140807-17-4
Chemical Name:
POMALIDOMIDE-PEG2-CO2H
Synonyms
NUN 07174;Poma-PEG2-COOH;Pomalidomide-PEG2-COOH;POMALIDOMIDE-PEG2-CO2H;Pomalidomide-PEG2-Acid;Thalidomide-4-NH-PEG2-COOH;Thalidomide-NH-PEG2-C2-COOH;Pomalidomide-PEG2-CO2H >=98%;Thalidomide-4-NH-PEG2-C2-COOH;3-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]propanoic Acid
CBNumber:
CB44744117
Molecular Formula:
C20H23N3O8
Molecular Weight:
433.41
MOL File:
2140807-17-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:09
Request For Quotation

POMALIDOMIDE-PEG2-CO2H Properties

Boiling point 744.6±60.0 °C(Predicted)
Density 1.456±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form powder or crystals
pka 4.28±0.10(Predicted)
color White to yellow

POMALIDOMIDE-PEG2-CO2H price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 901526 Pomalidomide-PEG2-CO2H 95% 2140807-17-4 50MG ₹77220 2022-06-14 Buy
Product number Packaging Price Buy
901526 50MG ₹77220 Buy

POMALIDOMIDE-PEG2-CO2H Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG2-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

POMALIDOMIDE-PEG2-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

POMALIDOMIDE-PEG2-CO2H Suppliers

Global( 34)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13193 58 Inquiry
Zhengzhou Lingzhiyue Technology Co., Ltd +86-0371-55074660 +86-13783527580 China 3152 58 Inquiry
Nanjing Bicbiotechnology Co., Ltd +86-2552131256 +86-18251840740 China 6000 58 Inquiry
Xian confluore Biological Technology Co., Ltd. +86-15680926068 +86-15680926068 China 2996 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 China 7176 65 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 China 41844 58 Inquiry
ChemShuttle, Inc. 0510-83588313-802 18800520310; China 3000 62 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 China 40035 58 Inquiry
Nanjing Bic Biotechnology Co., Ltd 025-58906079 17352406906; China 6929 58 Inquiry
Supplier Advantage
Zhengzhou Alfa Chemical Co.,Ltd 58
Zhengzhou Lingzhiyue Technology Co., Ltd 58
Nanjing Bicbiotechnology Co., Ltd 58
Xian confluore Biological Technology Co., Ltd. 58
Aladdin Scientific 58
Daicel Chiral Technologies (China)CO.,LTD 65
Jilin Chinese Academy of Sciences-yanshen Technology 58
ChemShuttle, Inc. 62
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Nanjing Bic Biotechnology Co., Ltd 58

2140807-17-4(POMALIDOMIDE-PEG2-CO2H)Related Search:

Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG2-N3 Pomalidomide-PEG4-azide Pomalidomide-PEG2-butyl iodide E3 Ligase Ligand-Linker Conjugates 22
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 Pomalidomide-PEG1-azide Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-PEG3-CO2H
E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-NH2 POMALIDOMIDE-PEG2-ALKYNE
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POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG2-COOH Pomalidomide-PEG2-CO2H >=98% NUN 07174 Thalidomide-4-NH-PEG2-COOH Thalidomide-NH-PEG2-C2-COOH Propanoic acid, 3-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]- 3-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]propanoic Acid Thalidomide-4-NH-PEG2-C2-COOH 3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic Acid Poma-PEG2-COOH Pomalidomide-PEG2-Acid 2140807-17-4 APIs peg