4-Acetoxyindole
- CAS No.
- 5585-96-6
- Chemical Name:
- 4-Acetoxyindole
- Synonyms
- 1H-indol-4-yl acetate;2-(1H-indol-4-yl)acetate;Acetic acid 1H-indol-4-yl ester;ACETOXYINDOLE;4-ACETOXYINDOLE;4-acacetoxyindole;4-INDOLYL ACETATE;4-INDOXYL ACETATE;4-Acetoxy-1H-indole;4-Acetoxyindole 98%
- CBNumber:
- CB4477655
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MOL File:
- 5585-96-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/18 13:26:42
| Melting point | 100-102°C |
|---|---|
| Boiling point | 339.1±15.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 16.38±0.30(Predicted) |
| color | Off-White to Beige |
| InChI | InChI=1S/C10H9NO2/c1-7(12)13-10-4-2-3-9-8(10)5-6-11-9/h2-6,11H,1H3 |
| InChIKey | ZXDMUHFTJWEDEF-UHFFFAOYSA-N |
| SMILES | N1C2=C(C(OC(=O)C)=CC=C2)C=C1 |
| CAS DataBase Reference | 5585-96-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 2933998090 |
4-Acetoxyindole Chemical Properties,Uses,Production
Description
4-acetoxylindole is also known as 4-Indolyl acetate. It can be used as standards of the reverse phase HPLC during separation of small molecules. It can also be used as reactant during the preparation of inhibitors of HIV-attachment, prostanoid EP3 antagonist, indolyl-nitroalkanes and psilocybin.
Uses
Reactant for preparation of:• ;Inhibitors of HIV-1 attachment1• ;Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent2• ;Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis3• ;Psilocybin as a medicinal agent4
General Description
4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.
References
http://www.sigmaaldrich.com/catalog/product/aldrich/259047?lang=en®ion=US
https://pubchem.ncbi.nlm.nih.gov/compound/4-Acetoxyindole
4-Acetoxyindole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JIVICHEM SYNTHESIS PVT LTD | +91-7028392790 +91-7028392790 | Maharashtra, India | 337 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Abintio Biosciences | 08048372058Ext 514 | Hyderabad, India | 52 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12962 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Suzhou Chukai Pharma Tech Co.,Ltd | +8615062531973 | China | 363 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12459 | 58 | Inquiry |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
| Guangzhou Tengyue Chemical Co., Ltd. | +86-86-18148706580 +8618826483838 | China | 153 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
5585-96-6(4-Acetoxyindole)Related Search:
1of4
chevron_right