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OLOMOUCINE II

OLOMOUCINE II Structure
CAS No.
500735-47-7
Chemical Name:
OLOMOUCINE II
Synonyms
Nsc736738;Olomoucine II - CAS 500735-47-7 - Calbiochem;Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine;2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol;Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-
CBNumber:
CB4504061
Molecular Formula:
C19H26N6O2
Molecular Weight:
370.45
MOL File:
500735-47-7.mol
Modify Date:
2023/7/14 17:34:45
Request For Quotation

OLOMOUCINE II Properties

Boiling point 618.5±65.0 °C(Predicted)
Density 1.32
storage temp. −20°C
solubility chloroform: 50 mg/mL, soluble
form powder
pka 9.83±0.30(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

OLOMOUCINE II price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 495621 Olomoucine II - CAS 500735-47-7 - Calbiochem A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B. 500735-47-7 5MG ₹28660 2022-06-14 Buy
Product number Packaging Price Buy
495621 5MG ₹28660 Buy

OLOMOUCINE II Chemical Properties,Uses,Production

General Description

A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B with an IC50 of 20 nM and displays increased potency over purvalanol A (Cat. No. 540500; IC50 = 50 nM), Roscovitine (Cat. No. 557360; IC50 = 450 nM), Bohemine (Cat. No. 203600; IC50 = 1.1 μM) and Olomoucine (Cat. No. 495620; IC50 = 7.0 μM). Further, exerts greater in vitro cytotoxicity in various cancer cell lines (IC50 = 3.0 μM, 5.3 μM, 6.3 μM, 6.3 μM and 11.1 μM for CEM, MCF7, HOS, G631 and K562, respectively).

Biochem/physiol Actions

Cell permeable: yes

OLOMOUCINE II Preparation Products And Raw materials

Raw materials

Preparation Products

OLOMOUCINE II Suppliers

Global( 11)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Santa Cruz Biotechnology, Inc. +1 (831) 457-3800 United States 3602 60 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
ChemeGen 中国 18818260767 China 6975 58 Inquiry
Tinib-Tools +420 (606) 323-943 United States 164 0 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Supplier Advantage
Aladdin Scientific 58
Santa Cruz Biotechnology, Inc. 60
Riedel-de Haen AG 87
SIGMA-RBI 91
Sigma-Aldrich 80
ChemeGen 中国 58
Tinib-Tools 0
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58

500735-47-7(OLOMOUCINE II)Related Search:

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NU6102 OLOMOUCINE
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Nsc736738 Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine 2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol Olomoucine II - CAS 500735-47-7 - Calbiochem Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]- 500735-47-7