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PURVALANOL A

PURVALANOL A Structure
CAS No.
212844-53-6
Chemical Name:
PURVALANOL A
Synonyms
NG-60;PurvaL;CH61386;CS-1631;PURVALANOL A;CDKinhibitor;(R)-Purvalanol A;NG 60;NG60;NG-60;PURVALANOLA, >98%;PurvalanolA/CH61386
CBNumber:
CB5283664
Molecular Formula:
C19H25ClN6O
Molecular Weight:
388.89
MOL File:
212844-53-6.mol
Modify Date:
2023/6/30 15:45:59

PURVALANOL A Properties

Boiling point 590.5±60.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility methylene chloride: 50 mg/mL, clear, colorless
form powder
pka 14.51±0.10(Predicted)
color off-white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
WGK Germany  3
HS Code  2933599590

PURVALANOL A price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P4484 Purvalanol A ≥98% (HPLC), powder 212844-53-6 1MG ₹14462.2 2022-06-14 Buy
Sigma-Aldrich(India) 540500 Purvalanol A - CAS 212844-53-6 - Calbiochem A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases. 212844-53-6 1MG ₹11880.01 2022-06-14 Buy
Product number Packaging Price Buy
P4484 1MG ₹14462.2 Buy
540500 1MG ₹11880.01 Buy

PURVALANOL A Chemical Properties,Uses,Production

Uses

Purvalanol A acts as a potent, cell-permeable CDK inhibitor used in the treatment of cell proliferative disorders. Anti-cancer.

Biological Activity

Cyclin-dependent kinase inhibitor. IC 50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Reversibly arrests synchronised cells in G1 and G2, and inhibits cell proliferation and cell death.

PURVALANOL A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 98)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25247 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9624 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry

PURVALANOL A Spectrum

PURVALANOL A NG-60 6-(3-CHLOROANILINO)-2(1R)-ISOPROPYL-2-HYDROXYETHYLAMINO-9-ISOPROPYLPURINE (2R)-2-[[6-[(3-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL 2-(1R-ISOPROPOYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE 2-(1R-ISOPROPYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYL-PURINE CH61386 2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanolCDKinhibitor. PurvalanolA,CDKinhibitor CDKinhibitor PurvalanolA/CH61386 Purvalanol A(NG 60) (R)-Purvalanol A (R)-2-(6-(3-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino)-3-methylbutan-1-ol NG-60, 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine Purvalanol A - CAS 212844-53-6 - Calbiochem NG 60;NG60;NG-60 CS-1631 PURVALANOLA, >98% PurvaL 1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)- PURVALANOL A USP/EP/BP (2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol 212844-53-6 C19H25ClN6O BioChemical Cell Biology Cell Signaling and Neuroscience Cell Cycle Regulators Cell Cycle Apoptosis and Cell Cycle Inhibitors Signalling