ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cell Cycle >CDK inhibitors >PURVALANOL A
PURVALANOL A
- CAS No.
- 212844-53-6
- Chemical Name:
- PURVALANOL A
- Synonyms
- NG-60;PurvaL;CH61386;CS-1631;PURVALANOL A;CDKinhibitor;(R)-Purvalanol A;NG 60;NG60;NG-60;PURVALANOLA, >98%;PurvalanolA/CH61386
- CBNumber:
- CB5283664
- Molecular Formula:
- C19H25ClN6O
- Molecular Weight:
- 388.89
- MOL File:
- 212844-53-6.mol
- Modify Date:
- 2023/6/30 15:45:59
Boiling point | 590.5±60.0 °C(Predicted) |
---|---|
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | methylene chloride: 50 mg/mL, clear, colorless |
form | powder |
pka | 14.51±0.10(Predicted) |
color | off-white |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P271-P261-P280 |
WGK Germany | 3 |
HS Code | 2933599590 |
PURVALANOL A price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P4484 | Purvalanol A ≥98% (HPLC), powder | 212844-53-6 | 1MG | ₹14462.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 540500 | Purvalanol A - CAS 212844-53-6 - Calbiochem A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases. | 212844-53-6 | 1MG | ₹11880.01 | 2022-06-14 | Buy |
PURVALANOL A Chemical Properties,Uses,Production
Uses
Purvalanol A acts as a potent, cell-permeable CDK inhibitor used in the treatment of cell proliferative disorders. Anti-cancer.
Biological Activity
Cyclin-dependent kinase inhibitor. IC 50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Reversibly arrests synchronised cells in G1 and G2, and inhibits cell proliferation and cell death.
PURVALANOL A Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 98)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25247 | 58 | Inquiry |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9624 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
212844-53-6(PURVALANOL A)Related Search:
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PURVALANOL A
NG-60
6-(3-CHLOROANILINO)-2(1R)-ISOPROPYL-2-HYDROXYETHYLAMINO-9-ISOPROPYLPURINE
(2R)-2-[[6-[(3-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
2-(1R-ISOPROPOYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE
2-(1R-ISOPROPYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYL-PURINE
CH61386
2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanolCDKinhibitor.
PurvalanolA,CDKinhibitor
CDKinhibitor
PurvalanolA/CH61386
Purvalanol A(NG 60)
(R)-Purvalanol A
(R)-2-(6-(3-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino)-3-methylbutan-1-ol
NG-60, 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
Purvalanol A - CAS 212844-53-6 - Calbiochem
NG 60;NG60;NG-60
CS-1631
PURVALANOLA, >98%
PurvaL
1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
PURVALANOL A USP/EP/BP
(2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
212844-53-6
C19H25ClN6O
BioChemical
Cell Biology
Cell Signaling and Neuroscience
Cell Cycle Regulators
Cell Cycle
Apoptosis and Cell Cycle
Inhibitors
Signalling