OLOMOUCINE
- CAS No.
- 101622-51-9
- Chemical Name:
- OLOMOUCINE
- Synonyms
- OLOMOUCINE;NSC 666096;Olomoucine,highpurity;OLOMOUCINE SYNTHETIC >95%;Olomoucine,98%,high purity;N2-[(2-HYDROXYETHYL)]-N6-BENZYLADENINE;Olomoucine - CAS 101622-51-9 - Calbiochem;5-Bromo-21-fluorobenzylamine&hydrochloride;2-(hydroxyethylamino)-6-benzylamino-9-methylpurine;6-BENYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE
- CBNumber:
- CB0309080
- Molecular Formula:
- C15H18N6O
- Molecular Weight:
- 298.34
- MOL File:
- 101622-51-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/4 15:50:00
| Melting point | 120-130 °C |
|---|---|
| Boiling point | 579.6±60.0 °C(Predicted) |
| Density | 1.36 |
| storage temp. | -20°C |
| solubility | DMSO, Methanol (Slightly) |
| pka | 14.55±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| CAS DataBase Reference | 101622-51-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29339980 |
OLOMOUCINE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | O0886 | Olomoucine ≥98% (HPLC) | 101622-51-9 | 1MG | ₹8887.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O0886 | Olomoucine ≥98% (HPLC) | 101622-51-9 | 5MG | ₹32702.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 495620 | Olomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases. | 101622-51-9 | 1MG | ₹5880 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 495620 | Olomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases. | 101622-51-9 | 5MG | ₹22650 | 2022-06-14 | Buy |
OLOMOUCINE Chemical Properties,Uses,Production
Chemical Properties
white to off-white solid
Biological Activity
Cyclin-dependent kinase inhibitor that competes for the ATP binding site of the kinase. Selectively inhibits cdc2/cyclin B (IC 50 = 7 μ M), cdk2/cyclin A (IC 50 = 7 μ M), cdk2/cyclin E (IC 50 = 7 μ M), cdk/p35 kinase (IC 50 = 3 μ M)? and ERK1/MAP kinase (IC 50 = 25 μ M). Arrests human fibroblasts in the G1 phase.
Enzyme inhibitor
This ATP site-competitive purine derivative (FW = 298.35 g/mol; CAS 101622-51-9), systematically named 6-benzylamino-2-[2-hydroxyethylamino]- 9-methylpurine, is a potent inhibitor of cyclin-dependent kinases, with an IC50 value of 7 μM for both cdk1 and cdk2 and an IC50 value of 3 μM for cdk5, arresting cells in G1. Olomoucine also inhibits cytokinin 7b-glucosyltransferase.
OLOMOUCINE Preparation Products And Raw materials
Raw materials
Preparation Products
OLOMOUCINE Suppliers
Global( 75)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Hubei Chuchang Biotech Co., Ltd. | +86-18727130788 +86-18727130788 | China | 109 | 58 | Inquiry |
| RD International Technology Co., Limited | 18024082417 | China | 9155 | 58 | Inquiry |
| InvivoChem | 13549236410 | China | 6749 | 58 | Inquiry |
| Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
| Sigma-Aldrich | 021-61415566 800-8193336 | China | 51471 | 80 | Inquiry |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | China | 12308 | 58 | Inquiry |
| MedChemExpress | 021-58955995 | United States | 6398 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CLEARSYNTH LABS LTD. | 58 |
| Career Henan Chemica Co | 58 |
| InvivoChem | 58 |
| Hubei Chuchang Biotech Co., Ltd. | 58 |
| RD International Technology Co., Limited | 58 |
| InvivoChem | 58 |
| Energy Chemical | 58 |
| Sigma-Aldrich | 80 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
| MedChemExpress | 58 |
101622-51-9(OLOMOUCINE)Related Search:
2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE
AMINOPURVALANOL A
ARCYRIAFLAVIN A
Roscovitine
SELICICLIB
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6-BENYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE
6-BENZYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE
2-(2'-Hydroxyethylamino)-9-methyl-6-(benzylamino)purine
2-(hydroxyethylamino)-6-benzylamino-9-methylpurine
2-[[9-METHYL-6[(PHENYLMETHYL)AMINO]-9H-PURIN-2-YL]AMINO]-ETHANOL
2-(2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-METHYLPURINE
N2-[(2-HYDROXYETHYL)]-N6-BENZYLADENINE
OLOMOUCINE
OLOMOUCINE SYNTHETIC >95%
Olomoucine,highpurity
2-[(2-Hydroxyethyl)amino]-6-benzylamino-9-methyl-9H-purine
2-[[9-Methyl-6-(benzylamino)-9H-purine-2-yl]amino]ethanol
N-(2-Hydroxyethyl)-N'-benzyl-9-methyl-9H-purine-2,6-diamine
Olomoucine,98%,high purity
Olomoucine6-Benzylamino-2-(2-hydroxyethylamino)-9-methylpurine
2-(6-Benzylamino-9-methyl-9H-purin-2-ylamino)-ethanol Olomoucine
NSC 666096
Olomoucine - CAS 101622-51-9 - Calbiochem
2-((6-(Benzylamino)-9-methyl-9H-purin-2-yl)amino)ethanol
Ethanol, 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-
5-Bromo-21-fluorobenzylamine&hydrochloride
Olomoucine,Inhibitor,cyclindependent kinases,cdc2,purines,cell cycle,non-small cell lung cancer cell line,MR6.5,protein kinases,Cyclin dependent kinase,CDK,xenopus laevis oocytes,proliferation,inhibit,cdk2
101622-51-9
C15H18N6O
Cell Signaling and Neuroscience
Cell Cycle Regulators
Cell Cycle
Cell Biology
Apoptosis and Cell Cycle
BioChemical
Heterocyclic Compounds
Bases & Related Reagents
Heterocycles
Inhibitors
inhibitor
Nucleotides
Protein Kinase