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Ro 3306

Ro 3306 Structure
CAS No.
872573-93-8
Chemical Name:
Ro 3306
Synonyms
CS-770;Ro 3306;RO3306;RO 3306;Ro 3306 USP/EP/BP;5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone;(5Z)-5-Quinolin-6-ylmethylene-2-[(thiophen-2-ylmethyl)-amino]-thiazol-4-one;(Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one;4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)-;(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one;2-[[(Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one
CBNumber:
CB92535693
Molecular Formula:
C18H13N3OS2
Molecular Weight:
351.45
MOL File:
872573-93-8.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

Ro 3306 Properties

Boiling point 569.1±60.0 °C(Predicted)
Density 1.41
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL, clear
pka 3.99±0.10(Predicted)
form powder
color white to light brown
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

WGK Germany  3

Ro 3306 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0569 RO-3306 ≥98% (HPLC) 872573-93-8 5MG ₹13856 2022-06-14 Buy
Sigma-Aldrich(India) SML0569 RO-3306 ≥98% (HPLC) 872573-93-8 25MG ₹56387.43 2022-06-14 Buy
TCI Chemicals (India) R0201 RO-3306 872573-93-8 10MG ₹8200 2022-05-26 Buy
TCI Chemicals (India) R0201 RO-3306 872573-93-8 50MG ₹14200 2022-05-26 Buy
Product number Packaging Price Buy
SML0569 5MG ₹13856 Buy
SML0569 25MG ₹56387.43 Buy
R0201 10MG ₹8200 Buy
R0201 50MG ₹14200 Buy

Ro 3306 Chemical Properties,Uses,Production

Uses

RO-3306 is an ATP-competitive and selective CDK1 inhibitor used against a diverse panel of human kinases. Used in the treatment of malignant tumors in conjunction with PARP inhibitors.

Biochem/physiol Actions

RO-3306 is a selective ATP-competitive inhibitor of CDK1. It inhibites CDK1 cyclin B1 activity with Ki of 35 nM, nearly 10-fold selectivity relative to CDK2/cyclin E and over 50-fold relative to CDK4/cyclin D. RO-3306 has been used to cause cell cycle arrest at the G2/M boundary.

Ro 3306 Preparation Products And Raw materials

Raw materials

Preparation Products

Ro 3306 Suppliers

Global( 112)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
Accela ChemBio Inc. +1-858-6993322 United States 19479 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Supplier Advantage
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
ATK CHEMICAL COMPANY LIMITED 60
Accela ChemBio Inc. 58
career henan chemical co 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58

Ro 3306 Spectrum

Ro 3306(872573-93-8)1HNMR

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Ro 3306 2-[[(Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one (Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one (5Z)-5-Quinolin-6-ylmethylene-2-[(thiophen-2-ylmethyl)-amino]-thiazol-4-one 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone RO3306;RO 3306 4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)- (5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one CS-770 Ro 3306 USP/EP/BP 872573-93-8 Inhibitors