N-(tert-Butoxycarbonyl)-L-phenylalanine
![N-(tert-Butoxycarbonyl)-L-phenylalanine Structure](CAS/GIF/13734-34-4.gif)
- CAS No.
- 13734-34-4
- Chemical Name:
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- Synonyms
- BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
- CBNumber:
- CB4781305
- Molecular Formula:
- C14H19NO4
- Molecular Weight:
- 265.3
- MOL File:
- 13734-34-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 17:49:17
Melting point | 85-87 °C(lit.) |
---|---|
Boiling point | 408.52°C (rough estimate) |
Density | 1.1356 (rough estimate) |
refractive index | 24.5 ° (C=1, EtOH) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone. |
form | Fine Crystalline Powder |
pka | 3.88±0.10(Predicted) |
color | White |
optical activity | [α]20/D +25±1°, c = 1% in ethanol |
BRN | 2219729 |
CAS DataBase Reference | 13734-34-4(CAS DataBase Reference) |
EPA Substance Registry System | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P271 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 36-22-36/37/38-20/21/22 | |||||||||
Safety Statements | 39-26-36-24/25 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29242990 | |||||||||
NFPA 704 |
|
N-(tert-Butoxycarbonyl)-L-phenylalanine price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 8.53006 | Boc-Phe-OH Novabiochem? | 13734-34-4 | 25G | ₹3080.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.53006 | Boc-Phe-OH Novabiochem? | 13734-34-4 | 100G | ₹6280 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.53006 | Boc-Phe-OH Novabiochem? | 13734-34-4 | 8530061000 | ₹84990 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 15480 | Boc-Phe-OH ≥99.0% (T) | 13734-34-4 | 5G | ₹2543.88 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 15480 | Boc-Phe-OH ≥99.0% (T) | 13734-34-4 | 25G | ₹6516.65 | 2022-06-14 | Buy |
N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Uses,Production
Chemical Properties
N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder
Uses
N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
Preparation
Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).
N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Advantage |
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GLR Innovations | 58 |
NSR Laboratories Pvt. Ltd. | 58 |
ADVENT CHEMBIO PRIVATE LIMITED | 58 |
J S LABS | 58 |
TYNDAL LABS PVT LTD | 58 |
AMINO ORGANICS | 58 |
TEADUS PHARMA PRIVATE LIMITED | 58 |
SV CHEM INTERMEDITES PRIVATE LIMITED | 58 |
JSK Chemicals | 58 |
SIDDHI VINAYAKA SPECHEM PVT LTD | 58 |
N-(tert-Butoxycarbonyl)-L-phenylalanine Spectrum
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