2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester

2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Structure
CAS No.
136285-67-1
Chemical Name:
2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester
Synonyms
Azilsartan SM1 impurity;Candesartan Nitro Impurity;Candesartan Cilexetil PGI 5;Candesartan ester intermediate C4;Candesartan Cilexetil Impurity 45;Candesartan Cilexetil Impurity C4;Ethyl-2-[[(2'-cyanobiphenyl-4-yl)methyl];CANDESARTAN INTERMEDIATES ( ETHYL ESTER C4 );Ethyl(2-ethoxy-1-benzimidazole)-7-carboxylate;Ethyl 2- [(2-cyanobenz-4-yl) methyl] amino] -3-nitrobenzoate
CBNumber:
CB4855237
Molecular Formula:
C23H19N3O4
Molecular Weight:
401.41
MOL File:
136285-67-1.mol
MSDS File:
SDS
Modify Date:
2023/7/28 17:44:41

2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Properties

Melting point >209°C (dec.)
Boiling point 602.9±55.0 °C(Predicted)
Density 1.31
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka -2.57±0.10(Predicted)
form Solid
color Yellow

SAFETY

Risk and Safety Statements

HS Code  2916399090

2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Chemical Properties,Uses,Production

Chemical Properties

Yellow crystalline solid

Uses

Ethyl 2-[N-[(2''-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate is a useful reagent in synthesis of candesartan cilexitil.

2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl(2-ethoxy-1-benzimidazole)-7-carboxylate Ethyl-2-[(2'-cyanobiphenyl-4-yl)Methyl aMino]-3-nitrobenzoate (C4) Ethyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate Candesartan ester intermediate C4 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Ethyl-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Benzoic acid,2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-, ethyl ester Ethyl 2-[N-[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Candesartan Cilexetil PGI 5 Ethyl-2-[[(2'-cyanobiphenyl-4-yl)methyl] 2-[[4-(2-cyanophenyl)phenyl]methylamino]-4-ethyl-3-nitrobenzoate Candesartan Nitro Impurity CANDESARTAN INTERMEDIATES ( ETHYL ESTER C4 ) Azilsartan SM1 impurity Candesartan Cilexetil Impurity 45 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate Ethyl 2-[N-[(2-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoateQ: What is Ethyl 2-[N-[(2-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Q: What is the CAS Number of Ethyl 2-[N-[(2-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate Candesartan Cilexetil Impurity C4 Ethyl 2- [(2-cyanobenz-4-yl) methyl] amino] -3-nitrobenzoate Ethyl-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate 2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester Ethyl 2-[[(2-Cyano[1,1-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid 136285-67-1 C23H19N3O4 API intermediates