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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Structure
CAS No.
16899-81-3
Chemical Name:
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
Synonyms
U 12844A;Isoprenaline impurity A;Norepinephrine Impurity 10;Isoprenaline EP Impurity A;Isoprenaline impurity A CRS;Isoprenaline EP Impurity A HCl;Isoprenaline HCl EP Impurity A;Isoprenaline HCl EP Impurity A HCl;Isoprenaline hydrochloride EP Impurity A;3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
CBNumber:
CB4912824
Molecular Formula:
C11H15NO3.ClH
Molecular Weight:
245.704
MOL File:
16899-81-3.mol
Modify Date:
2023/4/23 13:52:06
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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Properties

Melting point 255-257℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Chemical Properties,Uses,Production

Uses

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.

Preparation

Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Preparation Products And Raw materials

Raw materials

2-amino-1-(3,4-dihydroxyphenyl)ethan-1-one 2-Chloropropane 2-Chloro-3',4'-dihydroxyacetophenone Catechol Isopropylamine

Preparation Products

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Suppliers

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SKVen Technologies Pvt.Ltd. +91-7032295152 +91-7032295152 Hyderabad, India 81 58 Inquiry
Riddhesh Pharmachem +91-9106014993 +91-9106014993 Gujarat, India 126 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shanghai Time Chemicals CO., Ltd. +86-021-57951555 +8617317452075 China 1807 55 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13127 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Supplier Advantage
SKVen Technologies Pvt.Ltd. 58
Riddhesh Pharmachem 58
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Shanghai Time Chemicals CO., Ltd. 55
BOC Sciences 58
Zhengzhou Alfa Chemical Co.,Ltd 58
China National Standard Pharmaceutical Corporation Limited 58
Zibo Hangyu Biotechnology Development Co., Ltd 58

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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1) 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride Isoprenaline impurity A U 12844A [2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE Norepinephrine Impurity 10 Isoprenaline EP Impurity A HCl Isoprenaline EP Impurity A Isoprenaline impurity A CRS Isoprenaline HCl EP Impurity A HCl Isoprenaline hydrochloride EP Impurity A Isoprenaline Hydrochloride Impurity 1（Isoprenaline Hydrochloride EP Impurity A） Isoprenaline HCl EP Impurity A 1-(3,4-dihydroxyphenyl)-2-(isopropyl amino) ethan-1-one Hydrochloride 3，4-dihydroxyphenyl isopropylamino-methyl ketone hydrochloride 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride (Isoprenaline HCl Impurity) 16899-81-3