Amiloride hydrochloride
- CAS No.
- 2016-88-8
- Chemical Name:
- Amiloride hydrochloride
- Synonyms
- Arumil;AMipraMizi;AMIPRAMIDIN;amiprazidine;AMipraMidine;AMIPRAMIZIDE;GUANAMPRAZINE;AMILORIDE HCL;amiloridechloride;HCL AMILORIDE HCL
- CBNumber:
- CB5290772
- Molecular Formula:
- C6H8ClN7O.ClH
- Molecular Weight:
- 266.09
- MOL File:
- 2016-88-8.mol
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 293-294°C |
|---|---|
| storage temp. | Store at RT |
| solubility | H2O: 50 mg/mL, clear, yellow-green |
| form | powder |
| color | yellow |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| BCS Class | 1 |
| CAS DataBase Reference | 2016-88-8(CAS DataBase Reference) |
| EPA Substance Registry System | Amiloride hydrochloride (2016-88-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25-36/37/38 | |||||||||
| Safety Statements | 36-45-26 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UQ2275500 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29339980 | |||||||||
| NFPA 704 |
|
Amiloride hydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A7410 | Amiloride hydrochloride hydrate ≥98% (HPLC), powder | 2016-88-8 | 1G | ₹7674.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7410 | Amiloride hydrochloride hydrate ≥98% (HPLC), powder | 2016-88-8 | 5G | ₹28415.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7410 | Amiloride hydrochloride hydrate ≥98% (HPLC), powder | 2016-88-8 | 10G | ₹43170.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 129876 | Amiloride, Hydrochloride - CAS 2016-88-8 - Calbiochem An inhibitor of angiogenesis. | 2016-88-8 | 100MG | ₹8030 | 2022-06-14 | Buy |
Amiloride hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
Sodium channel blocker. Diuretic.
Definition
ChEBI: A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.
General Description
Crystalline solid or very light yellow powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A halogenated amine and amide, acidic salt. In aqueous solution, behaves as a weak acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
SYMPTOMS: Symptoms of exposure to Amiloride hydrochloride include headache, weakness, fatigue, back, chest, neck, shoulder or extremity pain; nausea, anorexia, vomiting, abdominal pain, hyperkalemia, paresthesias, shock, dizziness, coughing, shortness of breath, depression, nervousness, flaccid paralysis of the extremities, bradycardia, flatulence, skin rash, gas pain, constipation and dyspnea.
Fire Hazard
Flash point data for Amiloride hydrochloride are not available; however, Amiloride hydrochloride is probably combustible.
Biological Activity
Na + channel blocker. Defines the I 2A -amiloride sensitive and I 2B -amiloride insensitive imidazoline binding sites. Also inhibits TRPP3 channels.
Amiloride hydrochloride Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Bal Pharma Limited | +91-8041379581 +91-8041379500 | Karnataka, India | 20 | 58 | Inquiry |
| Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Ralington Pharma. | 91-79-48911722 | Gujarat, India | 311 | 58 | Inquiry |
| Sign Pharma Trade Services Pvt., Ltd.(SPTS) | 91-22-23481235 | Mumbai, India | 160 | 58 | Inquiry |
| Globofarm International Private Limited | 91-22-49716506 | Maharashtra, India | 188 | 58 | Inquiry |
| B. Shah & Sons | 08048361248Ext 407 | Mumbai, India | 79 | 58 | Inquiry |
| Aster International Pharmaceuticals LLP | 91-9321444153 | Maharashtra, India | 113 | 58 | Inquiry |
| Shubham Pharmachem Pvt., Ltd. | 91-22-26354800 | Maharashtra, India | 97 | 58 | Inquiry |
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