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2-Chloropropane

2-Chloropropane Structure
CAS No.
75-29-6
Chemical Name:
2-Chloropropane
Synonyms
ISOPROPYL CHLORIDE;2-CHLOROPROP-1-ENE;2-CHLORO-1-PROPENE;2-chloropropane(isopropylchloride);R280da;Isoprid;Narcosop;iso-C3H7Cl;2-Chlorpropan;2-CHLOROPROPANE
CBNumber:
CB9854220
Molecular Formula:
C3H7Cl
Molecular Weight:
78.54
MOL File:
75-29-6.mol
MSDS File:
SDS
Modify Date:
2024/8/15 16:24:08

2-Chloropropane Properties

Melting point -118 °C
Boiling point 35 °C
Density 0.859 g/mL at 25 °C(lit.)
vapor pressure 28.11 psi ( 55 °C)
refractive index n20/D 1.395(lit.)
Flash point −31 °F
storage temp. Store below +30°C.
solubility alcohol: miscible(lit.)
form clear liquid
color Colorless to Light yellow
explosive limit 2.8-10.7%(V)
Water Solubility 3.1 g/L (20 ºC)
Merck 14,5211
BRN 1730782
Stability Stable. Incompatible with strong oxidizing agents, strong bases. Highly flammable - note low flash point. Cool to zero C before opening.
CAS DataBase Reference 75-29-6(CAS DataBase Reference)
NIST Chemistry Reference Propane, 2-chloro-(75-29-6)
EPA Substance Registry System 2-Chloropropane (75-29-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P304+P340+P312
Hazard Codes  F+,Xi,Xn,F
Risk Statements  12-36/37-20/21/22-11-40
Safety Statements  9-29-36-26-16
RIDADR  UN 2456 3/PG 1
WGK Germany  3
RTECS  UC7200000
10-23
Autoignition Temperature 590 °C
TSCA  Yes
HazardClass  3
PackingGroup  I
HS Code  29031980
Toxicity LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
NFPA 704
4
2 0

2-Chloropropane price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.02809 2-Chloropropane for synthesis 75-29-6 100ML ₹5880 2022-06-14 Buy
Sigma-Aldrich(India) 8.02809 2-Chloropropane for synthesis 75-29-6 1L ₹8130 2022-06-14 Buy
Sigma-Aldrich(India) 8.02809 2-Chloropropane for synthesis 75-29-6 2.5L ₹16760 2022-06-14 Buy
Sigma-Aldrich(India) 240613 2-Chloropropane ≥99% 75-29-6 100ML ₹4262.2 2022-06-14 Buy
Sigma-Aldrich(India) 02489 2-Chloropropane analytical standard 75-29-6 5ML ₹16384.15 2022-06-14 Buy
Product number Packaging Price Buy
8.02809 100ML ₹5880 Buy
8.02809 1L ₹8130 Buy
8.02809 2.5L ₹16760 Buy
240613 100ML ₹4262.2 Buy
02489 5ML ₹16384.15 Buy

2-Chloropropane Chemical Properties,Uses,Production

Chemical Properties

Colourless liquid

Uses

2-Chloropropane decomposes by first-order reaction to give hydrogen chloride and propylene. It is a short-chain chlorinated paraffins that is a component in lubricant additives, metal processing, leather fat-liquoring, plastics softening, PVC plasticizing, flame retardants in paints, adhesives and sealants. It shows anesthetic properties. Further, it is used as an alternative foam-blowing agent.
2-Chloropropane is used as a solvent and an intermediate.It can be used as a reactant:
In the Friedel-Crafts alkylation reaction of difluorobenzene and toluene using solid acid and methylalumoxane catalysts, respectively.
To prepare 4-amino-3-iodo-1-(isopropyl)pyrazolo[3,4-d]pyrimidine, a key intermediate for the synthesis of PfPK7 kinase inhibitors.
It is used to prepare benzylisopropylphenylphosphine and chlorodiethylisopropylsilane.

General Description

A colorless liquid with a chloroform-like odor. Vapors heavier than air. Less dense than water. May irritate skin and eyes, and be narcotic in high concentrations. A fire and explosion risk. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Slightly soluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as 2-Chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Hazard

Highly flammable, fire and explosion risk, explosive limits in air 2.8–10.7%.

Health Hazard

ACUTE/CHRONIC HAZARDS: Fire hazard: Highly dangerous; when exposed to heat, flame or oxidizers. Explosion hazard: Moderate when exposed to heat or flame.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mutation data reported. A flammable liquid. A very dangerous fire hazard when exposed to heat, flame, or oxidners. When heated to decomposition it emits toxic fumes of Cl-. See also 1 CHLOROPROPANE.

Purification Methods

Purify the chloride with 95% H2SO4 as described for isopropyl bromide, then dry with MgSO4, P2O5 or CaH2, and fractionally distil it from Na2CO3 or CaH2. Alternatively, a stream of oxygen containing ca 5% ozone is passed through the chloride for about three times as long as is necessary to obtain the first coloration of starch iodide paper by the exit gas, and the liquid is then washed with NaHCO3 solution to hydrolyse ozonides and remove organic acids before drying and distilling. [Beilstein 1 IV 191.]

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