ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Structure
CAS No.
139481-44-0
Chemical Name:
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
Synonyms
Azilsartan-19;Azilsartan Impurity S;Azilsartan Impurity 21;Azilsartan Impurity 76;Azilsartan Impurity 27;Azilsartan Impurity 31;Azilsartan interMediate;Azilsartan interMediate B;Azilsartan Nitrile Methyl Ester;Azilsartan MedoxoMil InterMediate
CBNumber:
CB51009654
Molecular Formula:
C25H21N3O3
Molecular Weight:
411.45
MOL File:
139481-44-0.mol
MSDS File:
SDS
Modify Date:
2023/11/22 15:24:47

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Properties

Melting point 168 °C
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
form Solid
color Off-White to Light Yellow
InChI InChI=1S/C25H21N3O3/c1-3-31-25-27-22-10-6-9-21(24(29)30-2)23(22)28(25)16-17-11-13-18(14-12-17)20-8-5-4-7-19(20)15-26/h4-14H,3,16H2,1-2H3
InChIKey KSXLHOFDCDKQLH-UHFFFAOYSA-N
SMILES C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C#N)C=C2)C2=C(C(OC)=O)C=CC=C2N=1

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) M3197 Methyl 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 139481-44-0 25G ₹4800 2022-05-26 Buy
TCI Chemicals (India) M3197 Methyl 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 139481-44-0 100G ₹13600 2022-05-26 Buy
Product number Packaging Price Buy
M3197 25G ₹4800 Buy
M3197 100G ₹13600 Buy

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Chemical Properties,Uses,Production

Description

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate is a key synthetic intermediate in the synthesis of azilsartan, an angiotensin II.1 (AT1) receptor antagonist used in the treatment of hypertension.

Chemical Properties

Pale Yellow Solid

Uses

Intermediate in the synthesis of angiotensin II receptor antagonist.

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1H-BENZIMIDAZOLE-7-CARBOXYLICACID, 1-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-2-ETHOXY-METHYLESTER 1-(2-cyanobiphenyl-4-yl-methyl)- 2-ethoxybenzimidazole-7-carboxylic acid ethyl ester Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)Methyl)-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylate 1-[(2'-Cyano-1,1'-biphenyl-4-yl)Methyl]-2-ethoxy-7-benziMidazolecarboxylic Acid Methyl Ester 3-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxy-3H-benziMidazole-4-carboxylic Acid Methyl Ester Methyl 1-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxybenziMidazole-7-carbo Methyl 1-((2'-cyanobiphenyl-4-yl)Methyl)-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylate IH-BENZIMIDAZOLE-7-CARBOXXYLIC ACID,1-((2'-CYANO(1,1-BIPHENYL)-4-YL)METHYL)-2-ETHOXY-ETHYL ESTER Methyl1-[(2'-cyanobiphenyl-4-yl)Methyl]-2-ethoxy-benziMidazole-7-carboxylate MeEthyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl)Methyl]benziMidazole]-7 -carboxylate Azilsartan MedoxoMil InterMediate Azilsartan interMediate Methyl1-[(2'-cyanobiphenyl-4-yl)Methyl]-2-ethoxy-1H-benziMidazole-7-carboxylat Azilsartan interMediate B 1-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylic acid Methyl ester Candesartan ester intermediate (methyl C6) Azilsartan Impurity 21 Azilsartan Impurity 76 Methyl1-[(2'cynobiphenyl-4-yl)\methyl]-2-ethoxybenzimidazole-7-carboxylatedine-3-carboxylate Methyl1-[(2’cynobiphenyl-4-yl)\methyl]-2-ethoxybenzimidazole-7-carboxylate Azilsartan & Candesartan Cilexetil intermediates CANDESARTAN INTERMEDIATE(METHYL ESTER C6) 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic Acid Methyl Ester Methyl 1-[(2'-Cyanobiphenyl-4-yl) Methyl]-2-Ethoxy-1H-enzimidazole-7-Carboxylate Azilsartan Nitrile Methyl Ester Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate(C6 methylester) Candesartan (C6) methyl ester intermediates METHYL 1-(2'-CYANOBIPHENYL-4-YL)METHYL-2-ETHOXY BENZIMIDAZOLE-7-CARBOXYLATE(EBC-II) Azilsartan Impurity S Azilsartan Impurity 27 -cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate 3-[[4-(2-cyanophenyl)phenyl]methyl]-2-ethoxy-4-benzimidazolecarboxylic acid methyl ester methyl 1-((2'-cyano-[1,1'-biphenyl] Azilsartan impurity 20/Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate Azilsartan-19 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-, methyl ester Azilsartan Impurity 31 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2- ethoxy-1ethyl)-2-H-benzo[d]imidazole-7-carboxylate ethyl 3-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-Ethoxy-1H-Benzimidazole-7-Carboxylate [CDS-7] Methyl 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Methyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-ethoxy-1H-benzodimidazol-7-carboxylate Methyl 2-ethoxy-1-[(2'-cyanobiphenyl-4-yl)-methyl]-1Hbenzimidazole-7-carboxylate Methyl 3-((2'-cyanobiphenyl-4-yl) methyl)-2-ethoxy-3H-benzo [d]imidazole-4-carboxylate Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate Methyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-ethoxy-1H-benzodimidazol-7-carboxylate ethyl 3-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate Azilsartan Impurity 1 methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl) -2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 139481-44-0 1883681-10-1 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Intermediates