Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Forensic and veterinary standards >1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Structure
CAS No.
3820-67-5
Chemical Name:
1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
Synonyms
r1707;glifan;Alcidon;adalgur;Gilfanar;glifanar;privadol;alicidon;dolomate;glafenin
CBNumber:
CB5107351
Molecular Formula:
C19H17ClN2O4
Molecular Weight:
372.8
MOL File:
3820-67-5.mol
Modify Date:
2024/7/2 8:55:09
Request For Quotation

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Properties

Melting point 170℃
Boiling point 618℃
Density 1.428
refractive index 1.6800 (estimate)
Flash point 328℃
storage temp. 2-8°C(protect from light)
solubility DMSO:100.0(Max Conc. mg/mL);268.24(Max Conc. mM)
form Solid
pka pKa (20°C) 7.2
color Light yellow to yellow
Water Solubility 38.46g/L(temperature not stated)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  CB2687000
Toxicity LD50 orally in mice: >2 g/kg (Allais, Meier)

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Glafenine is a non-narcotic analgesic agent. Glafenine shows significant antiinflammatory activity. Glafenine is widely used for the treatment of pains of various origins.

Definition

ChEBI: A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain but high incidence of anaphylactic reactions resulted in their withdrawal from the market.

World Health Organization (WHO)

Glafenine, a quinolylanthranilate derivative, was introduced in 1965 for use as an analgesic. By the late 1970s its use had been associated with severe allergic responses, including anaphylactoid reactions, which led to its withdrawal in one country whereas in others a warning to this effect is required in the product information. In 1992, on the advice of the Committee for Proprietary Medicinal Products of the European Communities, glafenine was eventually withdrawn worldwide by the major manufacturer.

Hazard

Moderately toxic by ingestion. Human systemic effects.

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

2-Nitrobenzoyl chloride Hydrogen 4,7-Dichloroquinoline 2,2-Dimethyl-1,3-dioxolane-4-methanol

Preparation Products

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Suppliers

Global( 67)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9626 58 Inquiry
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 China 9003 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Henan Allgreen Chemical Co.,LTD +86-37155567971 +86-13633837469 China 5986 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Hangzhou FandaChem Co.,Ltd. 55
Finetech Industry Limited 58
Shaanxi Didu New Materials Co. Ltd 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Henan Allgreen Chemical Co.,LTD 58
LEAPCHEM CO., LTD. 58

3820-67-5(1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE)Related Search:

ETHYL ANTHRANILATE 7-Chloro-4-quinolinamine 4-(PHENYLAMINO)PYRIDINE 7-CHLORO-N-METHYLQUINOLIN-4-AMINE Methyl 2-(methylamino)benzoate
1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
chevron_left

1of2

chevron_right
GLAFENINE FREE BASE Glafeninum 1-glyceryl n-(7-chloro-4-quinolyl)anthranilate 2-[(7-Chloroquinolin-4-yl)amino]benzoic acid 2,3-dihydroxypropyl Alcidon Gilfanar 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate 2-[(7-chloro-4-quinolyl)amino]benzoic acid glyceryl ester 1-[N-(7-Chloro-4-quinolyl)anthranilate]glycerol 2,3-Dihydroxypropyl N-(7-chloro-4-quinolyl)anthranilate 2-[(7-Chloro-4-quinolinyl)aMino]benzoic Acid 2,3-Dihydroxypropyl Ester 2-[(7-Chloro-4-quinolyl)aMino]benzoic Acid α-Glyceride 4-[(2-Carboxyphenyl)aMino]-7-chloroquinoline α-Monoglyceride 4-[2-(β,γ-Dihydroxypropoxycarbonyl)phenylaMino]-7-chloroquinoline N-(7-Chloro-4-quinolyl)anthranilic Acid 2,3-Dihydroxypropyl Ester 2,3-Dihydroxypropyl-N-(7-chloro-4-quinolinyl)anthranilate glifanar glycerylaminophenaquine privadol r1707 GLAFENINE HYDROCHLORIDE 1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE 4-((2-carboxyphenyl)amino)-7-chloroquinolinealpha-monoglyceride 4-(2’-(beta,gamma-dihydroxypropoxycarbonyl)phenylamino)-7-chloroquinoleine 4-(2’-beta,gamma-dihydroxypropoxycarbonylphenylamino)-7-chloroquinoline adalgur alicidon anthranilicacid,n-(7-chloro-4-quinolyl)-,2,3-dihydroxypropylester benzoicacid,2-((7-chloro-4-quinolinyl)amino)-,2,3-dihydroxypropylester dolomate glafenin glafenine glaphenin glaphenine glicafan glifan glifanan Glafenine,inhibit,Inhibitor 3820-67-5 Analytical Standards Alphabetic Analytical Chromatography Product Catalog