ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Proline derivatives >(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
- CAS No.
- 114676-69-6
- Chemical Name:
- (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
- Synonyms
- (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;Boc-cis-4-Hydroxy-D-proline methyl ester;1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;Boc-Cis-D-Hyp-OMe;cis-Boc-d-Hyp-Ome;N-Boc-cis-D-Hyp-Ome;(2R,4R)-1-Boc-4-hydroxypyrroL;CIS-1-BOC-4-HYDROXY-D-PROLINATE;(Tert-Butoxy)Carbonyl D-cis-Hyp-OMe;Methyl cis-Boc-4-hydroxy-D-prolinate
- CBNumber:
- CB51118684
- Molecular Formula:
- C11H19NO5
- Molecular Weight:
- 245.27
- MOL File:
- 114676-69-6.mol
- Modify Date:
- 2023/12/20 17:11:56
| Melting point | 76 °C |
|---|---|
| Boiling point | 335.2±42.0 °C(Predicted) |
| alpha | 63° (C=1,EtOH) |
| Density | 1.216±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| form | Powder |
| pka | 14.27±0.40(Predicted) |
| color | White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | B5857 | N-(tert-Butoxycarbonyl)-cis-4-hydroxy-D-proline Methyl Ester min. 97.0 % | 114676-69-6 | 1G | ₹3200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B5857 | N-(tert-Butoxycarbonyl)-cis-4-hydroxy-D-proline Methyl Ester min. 97.0 % | 114676-69-6 | 5G | ₹9000 | 2022-05-26 | Buy |
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Chemical Properties,Uses,Production
Uses
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (N-Boc-cis-4-hydroxy-D-proline methyl ester) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 194)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Tulasi Labs | +91-8106722317 +91-8106722317 | Telangana, India | 44 | 58 | Inquiry |
| ARRKEM LIFE SCIENCES PRIVATE LIMITED | +91-8148739767 +91-8148739767 | Telangana, India | 260 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| PRISUN PHARMATECH CO.,LTD | +86-021-54326183-8001 +8618917565227 | China | 215 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | China | 1807 | 55 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10318 | 58 | Inquiry |
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(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester
(2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy
(2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate
Boc-Cis-D-Hyp-OMe
Methy cis-1-Boc-4-hydroxy-D-prolinate
Methyl cis-Boc-4-hydroxy-D-prolinate
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-
N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester
Methyl cis-1-Boc-4-hydroxy-D-prolinate
N-Boc-cis-4-hydroxy-D-proline methyl ester
Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate
(Tert-Butoxy)Carbonyl D-cis-Hyp-OMe
CIS-1-BOC-4-HYDROXY-D-PROLINATE
(2R,4R)-N-Boc-4-hydroxyproline methyl ester
(2R,4R)-N-Boc-cis-4-hydroxy-D-proline methyl ester
N-Boc-cis-D-Hyp-Ome
(2R,4R)-1-Boc-4-hydroxypyrroL
N-Boc-cis-4-hydroxy-D-prolinemethylester,95%
(2R,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE USP/EP/BP
O1-tert-Butyl O2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
cis-Boc-d-Hyp-Ome
1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
Boc-cis-4-Hydroxy-D-proline methyl ester
1-(1,1-Dimethylethyl) 2-methyl (2R,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
BOC cis D hydroxyproline methyl ester
114676-69-6