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LICOCHALCONE-A

LICOCHALCONE-A Structure
CAS No.
58749-22-7
Chemical Name:
LICOCHALCONE-A
Synonyms
CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Licochalcone A (10mg);Glycyrrhiza chalcone A
CBNumber:
CB5114580
Molecular Formula:
C21H22O4
Molecular Weight:
338.4
MOL File:
58749-22-7.mol
MSDS File:
SDS
Modify Date:
2024/1/3 18:42:19

LICOCHALCONE-A Properties

Melting point 100°
Boiling point 532.6±50.0 °C(Predicted)
Density 1.171±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka 7.82±0.15(Predicted)
form Yellow solid
color Yellow-orange
BRN 4534154
InChIKey KAZSKMJFUPEHHW-DHZHZOJOSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36/37
WGK Germany  3
RTECS  UB8755000
NFPA 704
0
3 0

LICOCHALCONE-A price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 435800 Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem An estrogenic flavonoid with anti-tumor and antiparasitic properties. 58749-22-7 10MG ₹10550.01 2022-06-14 Buy
Sigma-Aldrich(India) 68783 Licochalcone A ≥96.0% (HPLC) 58749-22-7 10MG ₹25752.68 2022-06-14 Buy
Sigma-Aldrich(India) 435800 Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem An estrogenic flavonoid with anti-tumor and antiparasitic properties. 58749-22-7 50MG ₹41350 2022-06-14 Buy
Product number Packaging Price Buy
435800 10MG ₹10550.01 Buy
68783 10MG ₹25752.68 Buy
435800 50MG ₹41350 Buy

LICOCHALCONE-A Chemical Properties,Uses,Production

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 268)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Chongqing Zhihe Biopharmaceutical Co., Ltd. +86-18580541567 +86-17782035140 China 301 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
Shaanxi Pioneer Biotech Co., Ltd . +8613259417953 China 3000 58 Inquiry
LICOCHALCONE-A (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- 7-Dimethoxycoumarin Licochalcone A, >=98% (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A Licochalcone A, >99% CS-919 Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Licocgalcone-A (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one 4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one Glycyrrhiza chalcone A Licorice Chalcone A Licoricchalcone A Licochalcone A (10mg) 58749-22-7 The group of Liquorice sy chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract